Use of the Novel Site-Directed Enzyme Enhancement Therapy (SEE-Tx) Drug Discovery Platform to Identify Pharmacological Chaperones for Glutaric Acidemia Type 1
Barroso M, Puchwein-Schwepcke A, Buettner L, Goebel I, Küchler K, Muntau A, Delgado A, Garcia-Collazo A, Martinell M, Barril X, Cubero E, Gersting S
J MED CHEM. 2024;67(19):17087-17100.

Functional studies drive treatment of phenylketonuria to become personalized
Gundorova P, Danecka M, Woidy M, Kasten V, Muntau A, Gersting S
EUR J HUM GENET. 2024;32(Suppl 1):698.

Glutaryl-CoA Dehydrogenase Misfolding in Glutaric Acidemia Type 1
Barroso M, Gertzen M, Puchwein-Schwepcke A, Preisler H, Sturm A, Reiss D, Danecka M, Muntau A, Gersting S
INT J MOL SCI. 2023;24(17):.

Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy
Braun F, Abed A, Sellung D, Rogg M, Woidy M, Eikrem O, Wanner N, Gambardella J, Laufer S, Haas F, Wong M, Dumoulin B, Rischke P, Mühlig A, Sachs W, von Cossel K, Schulz K, Muschol N, Gersting S, Muntau A, Kretz O, Hahn O, Rinschen M, Mauer M, Bork T, Grahammer F, Liang W, Eierhoff T, Römer W, Hansen A, Meyer-Schwesinger C, Iaccarino G, Tøndel C, Marti H, Najafian B, Puelles V, Schell C, Huber T
J CLIN INVEST. 2023;133(11):.

Long-Term Antibody Response to SARS-CoV-2 in Children
Dunay G, Barroso M, Woidy M, Danecka M, Engels G, Hermann K, Neumann F, Paul K, Beime J, Escherich G, Fehse K, Grinstein L, Haniel F, Haupt L, Hecher L, Kehl T, Kemen C, Kemper M, Kobbe R, Kohl A, Klokow T, Nörz D, Olfe J, Schlenker F, Schmiesing J, Schrum J, Sibbertsen F, Stock P, Tiede S, Vettorazzi E, Zazara D, Zapf A, Lütgehetmann M, Oh J, Mir T, Muntau A, Gersting S
J CLIN IMMUNOL. 2023;43(1):46-56.

Reduced Humoral and Cellular Immune Response to Primary COVID-19 mRNA Vaccination in Kidney Transplanted Children Aged 5–11 Years
Lalia J, Schild R, Lütgehetmann M, Dunay G, Kallinich T, Kobbe R, Massoud M, Oh J, Pietzsch L, Schulze-Sturm U, Schuetz C, Sibbertsen F, Speth F, Thieme S, Witkowski M, Berner R, Muntau A, Gersting S, Toepfner N, Pagel J, Paul K
VIRUSES-BASEL. 2023;15(7):1553.

A personalized medicine approach for phenylketonuria patients
Gundorova P, Danecka M, Woidy M, Gersting S
J INHERIT METAB DIS. 2022;45(S1):473.

Specific CD4+ T Cell Responses to Ancestral SARS-CoV-2 in Children Increase With Age and Show Cross-Reactivity to Beta Variant
Paul K, Sibbertsen F, Weiskopf D, Lütgehetmann M, Barroso M, Danecka M, Glau L, Hecher L, Hermann K, Kohl A, Oh J, Wiesch J, Sette A, Tolosa E, Vettorazzi E, Woidy M, Zapf A, Zazara D, Mir T, Muntau A, Gersting S, Dunay G
FRONT IMMUNOL. 2022;13:867577.

Phenotypic analysis of the pediatric immune response to SARS-CoV-2 by flow cytometry
Sibbertsen F, Glau L, Paul K, Mir T, Gersting S, Tolosa E, Dunay G
CYTOM PART A. 2022;101(3):220-227.

The first knock-in rat model for glutaric aciduria type I allows further insights into pathophysiology in brain and periphery
Gonzalez Melo M, Remacle N, Cudré-Cung H, Roux C, Poms M, Cudalbu C, Barroso M, Gersting S, Feichtinger R, Mayr J, Costanzo M, Caterino M, Ruoppolo M, Rüfenacht V, Häberle J, Braissant O, Ballhausen D
MOL GENET METAB. 2021;133(2):157-181.

Multiplexed complexome profiling using tandem mass tags
Guerrero-Castillo S, Krisp C, Küchler K, Arnold S, Schlüter H, Gersting S
BBA-BIOENERGETICS. 2021;1862(9):.

iBRET Screen of the ABCD1 Peroxisomal Network and Mutation-Induced Network Perturbations
Lotz-Havla A, Woidy M, Guder P, Friedel C, Klingbeil J, Bulau A, Schultze A, Dahmen I, Noll-Puchta H, Kemp S, Erdmann R, Zimmer R, Muntau A, Gersting S
J PROTEOME RES. 2021;20(9):4366-4380.

Edgetic Perturbations Contribute to Phenotypic Variability in PEX26 Deficiency
Lotz-Havla A, Woidy M, Guder P, Schmiesing J, Erdmann R, Waterham H, Muntau A, Gersting S
FRONT GENET. 2021;12:.

Neutropenia and intellectual disability are hallmarks of biallelic and de novo CLPB deficiency
Wortmann S, Ziętkiewicz S, Guerrero-Castillo S, Feichtinger R, Wagner M, Russell J, Ellaway C, Mróz D, Wyszkowski H, Weis D, Hannibal I, von Stülpnagel C, Cabrera-Orefice A, Lichter-Konecki U, Gaesser J, Windreich R, Myers K, Lorsbach R, Dale R, Gersting S, Prada C, Christodoulou J, Wolf N, Venselaar H, Mayr J, Wevers R
GENET MED. 2021;23(9):1705-1714.

Isoform-specific domain organization determines conformation and function of the peroxisomal biogenesis factor PEX26
Guder P, Lotz-Havla A, Woidy M, Reiß D, Danecka M, Schatz U, Becker M, Ensenauer R, Pagel P, Büttner L, Muntau A, Gersting S
BBA-MOL CELL RES. 2019;1866(3):518-531.

Secondary BH4 deficiency links protein homeostasis to regulation of phenylalanine metabolism
Eichinger A, Danecka M, Möglich T, Borsch J, Woidy M, Büttner L, Muntau A, Gersting S
HUM MOL GENET. 2018;27(10):1732-1742.

Inborn errors of metabolism and the human interactome: a systems medicine approach
Woidy M, Muntau A, Gersting S
J INHERIT METAB DIS. 2018;41(3):285-296.

Hepatocyte transplantation using the domino concept in a child with tetrabiopterin nonresponsive phenylketonuria
Stéphenne X, Debray F, Smets F, Jazouli N, Sana G, Tondreau T, Menten R, Goffette P, Boemer F, Schoos R, Gersting S, Najimi M, Muntau A, Goyens P, Sokal E
CELL TRANSPLANT. 2012;21(12):2765-70.

Letzte Aktualisierung aus dem FIS: 09.11.2024 - 10:58 Uhr