Leitung - Forschung
Strahlentherapie & Radioonkologie
Prof. Dr. med. Cordula Petersen
Medizinphysik & Medizinische Strahlenphysik
Dr. rer. nat. Tobias Gauer
Labor für Strahlenbiologie & Experimentelle Radioonkologie
Prof. Dr. rer. nat. Kai Rothkamm
Publikationen
Development and psychometric validation of a patient safety assessment tool in German Radiation Oncology: the PaSaGeRO Study protocol
Baehr A, Christalle E, Grohmann M, Scholl I
BMJ OPEN. 2024;14(8):e086214.
Usability and usefulness of (electronic) patient identification systems---A cross-sectional evaluation in German-speaking radiation oncology departments
Baehr A, Grohmann M, Guberina M, Schulze K, Lange T, Nestle U, Ernst P
STRAHLENTHER ONKOL. 2024;200(6):468-474.
Molecular refinement of pilocytic astrocytoma in adult patients
Bode H, Kresbach C, Holdhof D, Dorostkar M, Harter P, Hench J, Frank S, Suwala A, Schweizer L, Eckhardt A, Neyazi S, Bockmayr M, Wefers A, Schüller U
NEUROPATH APPL NEURO. 2024;50(1):e12949.
Successful implementation of online educational lectures of the German Society for Radiation Oncology (DEGRO)
Büttner M, Melton P, Fietkau R, Petersen C, Krause M, Borgmann K, Wolf U, Niyazi M, Christiansen H, Höller U, Schmitt D, Käsmann L, Linde P, Fleischmann D, Ziegler S, Bresch A, Mäurer M
STRAHLENTHER ONKOL. 2024;200(2):151-158.
Temporal change of DNA methylation subclasses between matched newly diagnosed and recurrent glioblastoma
Drexler R, Khatri R, Schüller U, Eckhardt A, Ryba A, Sauvigny T, Dührsen L, Mohme M, Ricklefs T, Bode H, Hausmann F, Huber T, Bonn S, Voß H, Neumann J, Silverbush D, Hovestadt V, Suvà M, Lamszus K, Gempt J, Westphal M, Heiland D, Hänzelmann S, Ricklefs F
ACTA NEUROPATHOL. 2024;147(1):21.
Synthesis and new DNA targeting activity of 6- and 7-tert-butylfascaplysins
Dyshlovoy S, Mansour W, Ramm N, Hauschild J, Zhidkov M, Kriegs M, Zielinski A, Hoffer K, Busenbender T, Glumakova K, Spirin P, Prassolov V, Tilki D, Graefen M, Bokemeyer C, von Amsberg G
SCI REP-UK. 2024;14(1):11788.
Mean global DNA methylation serves as independent prognostic marker in IDH wild type glioblastoma
Eckhardt A, Drexler R, Schoof M, Struve N, Capper D, Jelgersma C, Onken J, Harter P, Weber K, Divé I, Rothkamm K, Hoffer K, Klumpp L, Ganser K, Petersen C, Ricklefs F, Kriegs M, Schüller U
NEURO-ONCOLOGY. 2024;26(3):503-513.
Ikaros sets the threshold for negative B-cell selection by regulation of the signaling strength of the AKT pathway
Ehm P, Horn S, Hoffer K, Kriegs M, Horn M, Giehler S, Nalaskowski M, Rehbach C, Horstmann M, Jücker M
CELL COMMUN SIGNAL. 2024;22(1):360.
Digitalisierung und künstliche Intelligenz in der Radioonkologie
El Shafie R, Janssen S, Braulke F, Rieken S, Grohmann M
best practice onkologie. 2024;19:288-295.
Spontaneous metastasis xenograft models link CD44 isoform 4 to angiogenesis, hypoxia, EMT and mitochondria-related pathways in colorectal cancer
Everest-Dass A, Nersisyan S, Maar H, Novosad V, Schröder-Schwarz J, Freytag V, Stuke J, Beine M, Schiecke A, Haider M, Kriegs M, Elakad O, Bohnenberger H, Conradi L, Raygorodskaya M, Krause L, von Itzstein M, Tonevitsky A, Schumacher U, Maltseva D, Wicklein D, Lange T
MOL ONCOL. 2024;18(1):62-90.
Satisfaction with radiotherapy care among cancer patients treated in Germany-secondary analysis of a large multicenter study
Fabian A, Rühle A, Domschikowski J, Trommer M, Wegen S, Becker J, Wurschi G, Boeke S, Sonnhoff M, Fink C, Käsmann L, Schneider M, Bockelmann E, Treppner M, Mehnert-Theuerkauf A, Nicolay N, Krug D
STRAHLENTHER ONKOL. 2024;200(6):487-496.
Deutsche Gesellschaft für Radioonkologie (DEGRO) mahnt stationäre strahlentherapeutische Versorgung an: Stellungnahme zu einem Urteil des Bundessozialgerichts vom 29.08.2023 zur Erbringung stationärer strahlentherapeutischer Leistungen
Fietkau R, Höller U, van Kampen M, Krause M, Petersen C, Vordermark D
STRAHLENTHER ONKOL. 2024;200(2):107-108.
Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level
Godbole S, Voß H, Gocke A, Schlumbohm S, Schumann Y, Peng B, Mynarek M, Rutkowski S, Dottermusch M, Dorostkar M, Korshunov A, Mair T, Pfister S, Kwiatkowski M, Hotze M, Neumann P, Hartmann C, Weis J, Liesche-Starnecker F, Guan Y, Moritz M, Siebels B, Struve N, Schlüter H, Schüller U, Krisp C, Neumann J
NAT COMMUN. 2024;15(1):6237.
Multimodal image-guided laser ablation system for precise 3D tissue sampling and subsequent analysis of biomolecules for cancer research
Hahn J, Moritz M, Walter A, Wieck T, Moustafa A, Mansour W, Harms C, Stenzel P, Heeren J, Haider M, Lange T, Schlüter H
2024. Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXII. Tárnok A, Houston J (Hrsg.). 1. Aufl. Bellingham, Washington: SPIE , .
Survey in radiation oncology departments in Germany, Austria, and Switzerland: state of digitalization by 2023
Janssen S, El Shafie R, Grohmann M, Knippen S, Putora P, Beck M, Baehr A, Clemens P, Stefanowicz S, Rades D, Becker J, Fahlbusch F
STRAHLENTHER ONKOL. 2024;200(6):497-506.
International consensus statement on allergy and rhinology: Sinonasal tumors
Kuan E, Wang E, Adappa N, Beswick D, London N, Su S, Wang M, Abuzeid W, Alexiev B, Alt J, Antognoni P, Alonso-Basanta M, Batra P, Bhayani M, Bell D, Bernal-Sprekelsen M, Betz C, Blay J, Bleier B, Bonilla-Velez J, Callejas C, Carrau R, Casiano R, Castelnuovo P, Chandra R, Chatzinakis V, Chen S, Chiu A, Choby G, Chowdhury N, Citardi M, Cohen M, Dagan R, Dalfino G, Dallan I, Dassi C, de Almeida J, Tos A, DelGaudio J, Ebert C, El-Sayed I, Eloy J, Evans J, Fang C, Farrell N, Ferrari M, Fischbein N, Folbe A, Fokkens W, Fox M, Lund V, Gallia G, Gardner P, Geltzeiler M, Georgalas C, Getz A, Govindaraj S, Gray S, Grayson J, Gross B, Grube J, Guo R, Ha P, Halderman A, Hanna E, Harvey R, Hernandez S, Holtzman A, Hopkins C, Huang Z, Huang Z, Humphreys I, Hwang P, Iloreta A, Ishii M, Ivan M, Jafari A, Kennedy D, Khan M, Kimple A, Kingdom T, Knisely A, Kuo Y, Lal D, Lamarre E, Lan M, Le H, Lechner M, Lee N, Lee J, Lee V, Levine C, Lin J, Lin D, Lobo B, Locke T, Luong A, Magliocca K, Markovic S, Matnjani G, McKean E, Meço C, Mendenhall W, Michel L, Na'ara S, Nicolai P, Nuss D, Nyquist G, Oakley G, Omura K, Orlandi R, Otori N, Papagiannopoulos P, Patel Z, Pfister D, Phan J, Psaltis A, Rabinowitz M, Ramanathan M, Rimmer R, Rosen M, Sanusi O, Sargi Z, Schafhausen P, Schlosser R, Sedaghat A, Senior B, Shrivastava R, Sindwani R, Smith T, Smith K, Snyderman C, Solares C, Sreenath S, Stamm A, Stölzel K, Sumer B, Surda P, Tajudeen B, Thompson L, Thorp B, Tong C, Tsang R, Turner J, Turri-Zanoni M, Udager A, van Zele T, VanKoevering K, Welch K, Wise S, Witterick I, Won T, Wong S, Woodworth B, Wormald P, Yao W, Yeh C, Zhou B, Palmer J
INT FORUM ALLERGY RH. 2024;14(2):149-608.
Multidisciplinary survey on use of feeding tubes in head and neck cancer patients undergoing chemoradiotherapy in Germany-the SUFEETUBE project
Löser A, Fabian A, Rühle A, Thieme A, Baehr A, Käsmann L, Zwaan I, Kahle B, Soror T, Kunte A, Seyedi N, Kebenko M, Seidel C, Dierks F, Krause L, Bruchhage K, Rades D
STRAHLENTHER ONKOL. 2024;200(7):583-594.
Deep learning-based conditional inpainting for restoration of artifact-affected 4D CT images
Madesta F, Sentker T, Gauer T, Werner R
MED PHYS. 2024;51(5):3437-3454.
Investigation of the possibility of shaping an electron dose field of a clinical accelerator with 3D printed polymer products
Miloichikova I, Bulavskaya A, Gargioni E, Grigorieva A, Cherepennikov Y, Belousov D, Stuchebrov S
NUCL INSTRUM METH A. 2024;1059:.
Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation
Neyazi S, Yamazawa E, Hack K, Tanaka S, Nagae G, Kresbach C, Umeda T, Eckhardt A, Tatsuno K, Pohl L, Hana T, Bockmayr M, Kim P, Dorostkar M, Takami T, Obrecht D, Takai K, Suwala A, Komori T, Godbole S, Wefers A, Otani R, Neumann J, Higuchi F, Schweizer L, Nakanishi Y, Monoranu C, Takami H, Engertsberger L, Yamada K, Ruf V, Nomura M, Mohme T, Mukasa A, Herms J, Takayanagi S, Mynarek M, Matsuura R, Lamszus K, Ishii K, Kluwe L, Imai H, von Deimling A, Koike T, Benesch M, Kushihara Y, Snuderl M, Nambu S, Frank S, Omura T, Hagel C, Kugasawa K, Mautner V, Ichimura K, Rutkowski S, Aburatani H, Saito N, Schüller U
ACTA NEUROPATHOL. 2024;147(1):22.
Pineal anlage tumor: clinical and diagnostic features, and rationales for treatment
Obrecht-Sturm D, Pfaff E, Mynarek M, Bison B, Rodehüser M, Becker M, Kietz S, Pfister S, Jones D, Sturm D, von Deimling A, Sahm F, Kortmann R, Schwarz R, Pietsch T, Fleischhack G, Rutkowski S
J NEURO-ONCOL. 2024;166(2):359-368.
Treatment response as surrogate to predict risk for disease progression in pediatric medulloblastoma with persistent MRI lesions after first-line treatment
Obrecht-Sturm D, Schömig L, Mynarek M, Bison B, Schwarz R, Pietsch T, Pfister S, Sill M, Sturm D, Sahm F, Kortmann R, Gerber N, von Bueren A, Fleischhack G, Schüller U, Nussbaumer G, Benesch M, Rutkowski S
NEURO-ONCOLOGY. 2024 [Epub ahead of print].
The Histogenetic Origin of Malignant Cells Predicts Their Susceptibility towards Synthetic Lethality Utilizing the TK.007 System
Pallasch F, Freytag V, Kriegs M, Gatzemeier D, Mair T, Voss H, Riecken K, Dawood M, Fehse B, Efferth T, Schlüter H, Schumacher U
CANCERS. 2024;16(12):.
Radiotherapie bei Vulva- und Vaginalkarzinom
Petersen C, Baehr A, Goy Y, Corradini S
ONKOLOGIE-GER. 2024;30:683–692.
Quantification of human papillomavirus cell-free DNA from low-volume blood plasma samples by digital PCR
Rosing F, Meier M, Schroeder L, Laban S, Hoffmann T, Kaufmann A, Siefer O, Wuerdemann N, Klußmann J, Rieckmann T, Alt Y, Faden D, Waterboer T, Höfler D
MICROBIOL SPECTR. 2024;12(7):e0002424.
Aqueous extracts from Dioscorea sansibarensis Pax show cytotoxic and radiosensitizing potential in 3D growing HPV-negative and HPV-positive human head and neck squamous cell carcinoma models
Schott M, Vehlow A, Benka M, Lagies S, Kammerer B, Rieckmann T, Cordes N
BIOMED PHARMACOTHER. 2024 [Epub ahead of print];179:117305.
Medulloblastoma in children with Fanconi anemia: Association with FA-D1/FA-N, SHH type and poor survival independent of treatment strategies
Sönksen M, Obrecht-Sturm D, Hernáiz Driever P, Sauerbrey A, Graf N, Kontny U, Reimann C, Langhein M, Kordes U, Schwarz R, Obser T, Boschann F, Schüller U, Altendorf L, Goschzik T, Pietsch T, Mynarek M, Rutkowski S
NEURO-ONCOLOGY. 2024 [Epub ahead of print].
Trifluridine/Tipiracil Based Chemoradiation in locally Advanced Rectal Cancer: The Phase I/II TARC Trial
Thiele B, Stein A, Schultheiß C, Paschold L, Jonas H, Goekkurt E, Rüssel J, Schuch G, Wierecky J, Sinn M, Tintelnot J, Petersen C, Rothkamm K, Vettorazzi E, Binder M
CLIN COLORECTAL CANC. 2024 [Epub ahead of print].
USP7 Deregulation Impairs S Phase Specific DNA Repair after Irradiation in Breast Cancer Cells
Vogt M, Classen S, Krause A, Peter N, Petersen C, Rothkamm K, Borgmann K, Meyer F
BIOMEDICINES. 2024;12(4):.
Benchmarking machine learning-based real-time respiratory signal predictors in 4D SBRT
Wimmert L, Nielsen M, Madesta F, Gauer T, Hofmann C, Werner R
MED PHYS. 2024;51(5):3173-3183.
Impact of breathing signal-guided dose modulation on step-and-shoot 4D CT image reconstruction
Wimmert L, Schwarz A, Gauer T, Hofmann C, Dickmann J, Sentker T, Werner R
MED PHYS. 2024 [Epub ahead of print].
Patient-Relevant Costs for Organ Preservation versus Radical Resection in Locally Advanced Rectal Cancer
Wurschi G, Rühle A, Domschikowski J, Trommer M, Ferdinandus S, Becker J, Boeke S, Sonnhoff M, Fink C, Käsmann L, Schneider M, Bockelmann E, Krug D, Nicolay N, Fabian A, Pietschmann K
CANCERS. 2024;16(7):.
Risk management patterns in radiation oncology-results of a national survey within the framework of the Patient Safety in German Radiation Oncology (PaSaGeRO) project
Baehr A, Hummel D, Gauer T, Oertel M, Kittel C, Löser A, Todorovic M, Petersen C, Krüll A, Buchgeister M
STRAHLENTHER ONKOL. 2023;199(4):350-359.
The prognostic impact of B7-H3 and B7-H4 in head and neck squamous cell carcinoma
Borgmann M, Oetting A, Meyer F, Möckelmann N, Droste C, von Bargen C, Möller-Koop C, Witt M, Borgmann K, Rothkamm K, Betz C, Münscher A, Clauditz T, Rieckmann T
J CANCER RES CLIN. 2023;149(7):3383-3393.
Traditional risk factors and nodal yield-still relevant with high-quality risk-adapted adjuvant treatment for locally advanced head and neck cancer?
Butt Y, Tennstedt P, Busch C, Hanken H, Krüll A, Petersen C, Tribius S
STRAHLENTHER ONKOL. 2023;199(3):284-292.
G2 checkpoint targeting via Wee1 inhibition radiosensitizes EGFRvIII-positive glioblastoma cells
Cetin M, Rieckmann T, Hoffer K, Riepen B, Christiansen S, Gatzemeier F, Feyerabend S, Schoof M, Schüller U, Petersen C, Mynarek M, Rothkamm K, Kriegs M, Struve N
RADIAT ONCOL. 2023;18(1):.
Crosstalk between immune checkpoint and DNA damage response inhibitors for radiosensitization of tumors
Classen S, Petersen C, Borgmann K
STRAHLENTHER ONKOL. 2023;199(12):1152-1163.
Epigenetic profiling reveals a strong association between lack of 5-ALA fluorescence and EGFR amplification in IDH-wildtype glioblastoma
Drexler R, Sauvigny T, Schüller U, Eckhardt A, Maire C, Khatri R, Hausmann F, Hänzelmann S, Huber T, Bonn S, Bode H, Lamszus K, Westphal M, Dührsen L, Ricklefs F
NEURO-ONCOL PRACT. 2023;10(5):462-471.
DNA methylation subclasses predict the benefit from gross total tumor resection in IDH-wildtype glioblastoma patients
Drexler R, Schüller U, Eckhardt A, Filipski K, Hartung T, Harter P, Divé I, Forster M, Czabanka M, Jelgersma C, Onken J, Vajkoczy P, Capper D, Siewert C, Sauvigny T, Lamszus K, Westphal M, Dührsen L, Ricklefs F
NEURO-ONCOLOGY. 2023;25(2):315-325.
SHIP1 Is Present but Strongly Downregulated in T-ALL, and after Restoration Suppresses Leukemia Growth in a T-ALL Xenotransplantation Mouse Model
Ehm P, Rietow R, Wegner W, Bußmann L, Kriegs M, Dierck K, Horn S, Streichert T, Horstmann M, Jücker M
CELLS-BASEL. 2023;12(13):1798.
Preclinical patient-derived modeling of castration-resistant prostate cancer facilitates individualized assessment of homologous recombination repair deficient disease
Elsesy M, Oh-Hohenhorst S, Oing C, Eckhardt A, Burdak-Rothkamm S, Alawi M, Müller C, Schüller U, Maurer T, von Amsberg G, Petersen C, Rothkamm K, Mansour W
MOL ONCOL. 2023;17(6):1129-1147.
Financial toxicity in cancer patients undergoing radiotherapy in a universal health care system - A prospective multicenter study of 1075 patients
Fabian A, Rühle A, Domschikowski J, Trommer M, Wegen S, Becker J, Wurschi G, Boeke S, Sonnhoff M, Fink C, Käsmann L, Schneider M, Bockelmann E, Treppner M, Krug D, Nicolay N
RADIOTHER ONCOL. 2023;183:109604.
Psychosocial distress in cancer patients undergoing radiotherapy: a prospective national cohort of 1042 patients in Germany
Fabian A, Rühle A, Domschikowski J, Trommer M, Wegen S, Becker J, Wurschi G, Boeke S, Sonnhoff M, Fink C, Käsmann L, Schneider M, Bockelmann E, Treppner M, Mehnert-Theuerkauf A, Krug D, Nicolay N
J CANCER RES CLIN. 2023;149(11):9017-9024.
Strukturelle, prozedurale und personelle Voraussetzung für die Erbringung radioonkologischer und strahlentherapeutischer Leistungen 2023 in Deutschland – ein Positionspapier der Deutschen Gesellschaft für Radioonkologie (DEGRO)
Fietkau R, Höller U, Krause M, Petersen C, van Kampen M, Vordermark D, Willner J
STRAHLENTHER ONKOL. 2023;199(8):697-705.
Irradiation dose to the swallowing apparatus impacts nutritional status in head and neck cancer patients-results from the prospective randomized HEADNUT trial
Finger A, Grohmann M, Krause L, Krüll A, Petersen C, Thieme A, Rades D, Löser A
STRAHLENTHER ONKOL. 2023;199(10):875-880.
DNA as the main target in radiotherapy-a historical overview from first isolation to anti-tumour immune response
Frey B, Borgmann K, Jost T, Greve B, Oertel M, Micke O, Eckert F
STRAHLENTHER ONKOL. 2023;199(12):1080-1090.
Clonogenicity-based radioresistance determines the expression of immune suppressive immune checkpoint molecules after hypofractionated irradiation of MDA-MB-231 triple-negative breast cancer cells
Gehre S, Meyer F, Sengedorj A, Grottker F, Reichardt C, Alomo J, Borgmann K, Frey B, Fietkau R, Rückert M, Gaipl U
FRONT ONCOL. 2023;13:981239.
Steigerung der Behandlungsqualität und Patientensicherheit durch ein automatisiertes 3D in-vivo Dosimetrie-Verfahren in der Strahlentherapie
Grohmann M
STRAHLENTHER ONKOL. 2023;2023(Sonderheft 1/2023):.
Benefits and considerations in using a novel computed tomography system optimized for radiotherapy planning
Grohmann M, Petersen C, Todorovic M
PHYS IMAG RADIAT ONC. 2023;28:.
Radiotherapy combined with docetaxel alters the immune phenotype of HNSCC cells and results in increased surface expression of CD137 and release of HMGB1 of specifically HPV-positive tumor cells
Grottker F, Gehre S, Reichardt C, Sengedorj A, Jost T, Rieckmann T, Hecht M, Gostian A, Frey B, Fietkau R, Gaipl U, Rückert M
NEOPLASIA. 2023;45:100944.
Discordant and Converting Receptor Expressions in Brain Metastases from Breast Cancer: MRI-Based Non-Invasive Receptor Status Tracking
Heitkamp A, Madesta F, Amberg S, Wahaj S, Schröder T, Bechstein M, Meyer L, Broocks G, Hanning U, Gauer T, Werner R, Fiehler J, Gellißen S, Kniep H
CANCERS. 2023;15(11):.
Das BRCA-like-Mammakarzinom profitiert von Cisplatin plus Veliparib; Ergebnisse der S1416-Phase-II-Studie
Hintelmann K, Borgmann K
STRAHLENTHER ONKOL. 2023;199(12):1258-1261.
Radiotherapeutic Strategies to Overcome Resistance of Breast Cancer Brain Metastases by Considering Immunogenic Aspects of Cancer Stem Cells
Hintelmann K, Petersen C, Borgmann K
CANCERS. 2023;15(1):.
Outcomes following oropharyngeal squamous cell carcinoma resection and bilateral neck dissection with or without contralateral postoperative radiotherapy of the pathologically node-negative neck
Jansen F, Betz C, Belau M, Matnjani G, Clauditz T, Rico S, Stölzel K, Möckelmann N, Böttcher A
EUR ARCH OTO-RHINO-L. 2023;280(8):3843-3853.
Increased Radiation Sensitivity in Patients with Phelan-McDermid Syndrome
Jesse S, Kuhlmann L, Hildebrand L, Magelssen H, Schmaus M, Timmermann B, Andres S, Fietkau R, Distel L
CELLS-BASEL. 2023;12(5):.
Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics
Johann P, Altendorf L, Efremova E, Holsten T, Steinbügl M, Nemes K, Eckhardt A, Kresbach C, Bockmayr M, Koch A, Haberler C, Antonelli M, DeSisto J, Schuhmann M, Hauser P, Siebert R, Bens S, Kool M, Green A, Hasselblatt M, Frühwald M, Schüller U
ACTA NEUROPATHOL. 2023;146(3):527-541.
Impact of AKT1 on cell invasion and radiosensitivity in a triple negative breast cancer cell line developing brain metastasis
Kempska J, Oliveira-Ferrer L, Grottke A, Qi M, Alawi M, Meyer F, Borgmann K, Hamester F, Eylmann K, Rossberg M, Smit D, Jücker M, Laakmann E, Witzel I, Schmalfeldt B, Müller V, Legler K
FRONT ONCOL. 2023;13:1129682.
Atypical Neurofibromas reveal distinct epigenetic features with proximity to benign peripheral nerve sheath tumor entities
Kresbach C, Dottermusch M, Eckhardt A, Ristow I, Paplomatas P, Altendorf L, Wefers A, Bockmayr M, Belakhoua S, Tran I, Pohl L, Neyazi S, Bode H, Farschtschi S, Well L, Friedrich R, Reuss D, Snuderl M, Hagel C, Mautner V, Schüller U
NEURO-ONCOLOGY. 2023;25(9):1644-1655.
Teaching in radiation oncology: now and 2025-results of a focus group with medical students
Linde P, Klein M, Lang F, Wegen S, Petersen C, Dapper H, Fan J, Celik E, Marnitz S, Baues C
STRAHLENTHER ONKOL. 2023;199(4):360-369.
Impaired DNA double-strand break repair and effective radiosensitization of HPV-negative HNSCC cell lines through combined inhibition of PARP and Wee1
Oetting A, Christiansen S, Gatzemeier F, Köcher S, Bußmann L, Böttcher A, Stölzel K, Hoffmann A, Struve N, Kriegs M, Petersen C, Betz C, Rothkamm K, Zech H, Rieckmann T
CLIN TRANSL RAD ONCO. 2023;41:100630.
Impact of Modern Low Dose Involved Site Radiation Therapy on Normal Tissue Toxicity in Cervicothoracic Non-Hodgkin Lymphomas: A Biophysical Study
Roers J, Rolf D, Baehr A, Pöttgen C, Stickan-Verfürth M, Siats J, Hering D, Moustakis C, Grohmann M, Oertel M, Haverkamp U, Stuschke M, Timmermann B, Eich H, Reinartz G
CANCERS. 2023;15(24):.
Dose-escalated re-irradiation improves outcome in locally recurrent head and neck cancer - Results of a large multicenter analysis
Roesch J, Oertel M, Wegen S, Trommer M, Schleifenbaum J, Hering D, Mäurer M, Knippen S, Dobiasch S, Waltenberger M, von der Grün J, Medenwald D, Süß C, Hoeck M, Käsmann L, Fleischmann D, Rühle A, Nicolay N, Fabian A, Löser A, Heß S, Tamaskovics B, Vinsensia M, Hecht M
RADIOTHER ONCOL. 2023;181:109380.
Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage signatures
Schoof M, Godbole S, Albert T, Dottermusch M, Walter C, Ballast A, Qin N, Olivera M, Göbel C, Neyazi S, Holdhof D, Kresbach C, Peter L, Epplen G, Thaden V, Spohn M, Blattner-Johnson M, Modemann F, Mynarek M, Rutkowski S, Sill M, Varghese J, Afflerbach A, Eckhardt A, Münter D, Verma A, Struve N, Jones D, Remke M, Neumann J, Kerl K, Schüller U
NAT COMMUN. 2023;14(1):7717.
Evaluation of a short instrument for measuring health-related quality of life in oncological patients in routine care (HELP-6): an observational study
Schrage T, Görlach M, Betz C, Bokemeyer C, Kroger N, Muller V, Krüll A, Schulz H, Bleich C
FRONT PSYCHOL. 2023;14:1158449.
Dose reduction in sequence scanning 4D CT imaging through respiratory signal-guided tube current modulation: A feasibility study
Schwarz A, Werner R, Wimmert L, Vornehm M, Gauer T, Hofmann C
MED PHYS. 2023;50(12):7539-7547.
Risk prediction in early childhood sonic hedgehog medulloblastoma treated with radiation-avoiding chemotherapy
Tonn S, Korshunov A, Obrecht D, Sill M, Spohn M, von Hoff K, Milde T, Pietsch T, Goschzik T, Bison B, Juhnke B, Struve N, Sturm D, Sahm F, Bockmayr M, Friedrich C, von Bueren A, Gerber N, Benesch M, Jones D, Kool M, Wefers A, Schüller U, Pfister S, Rutkowski S, Mynarek M
NEURO-ONCOLOGY. 2023;25(8):1518-1529.
Advances in molecular targeted therapies to increase efficacy of (chemo)radiation therapy
Viktorsson K, Rieckmann T, Fleischmann M, Diefenhardt M, Hehlgans S, Rödel F
STRAHLENTHER ONKOL. 2023;199(12):1091-1109.
Src family kinase targeting in head and neck tumor cells using SU6656, PP2 and dasatinib
Vu A, Akingunsade L, Hoffer K, Petersen C, Betz C, Rothkamm K, Rieckmann T, Bussmann L, Kriegs M
HEAD NECK-J SCI SPEC. 2023;45(1):147-155.
Development and characterization of modular mouse phantoms for end-to-end testing and training in radiobiology experiments
Wegner M, Frenzel T, Krause D, Gargioni E
PHYS MED BIOL. 2023;68(8):.
Classification of phantoms for medical imaging: The 33rd CIRP Design Conference
Wegner M, Gargioni E, Krause D
Procedia CIRP. 2023;119:1140-1145.
Clinical application of breathing-adapted 4D CT: image quality comparison to conventional 4D CT
Werner R, Szkitsak J, Madesta F, Büttgen L, Wimmert L, Sentker T, Fietkau R, Haderlein M, Bert C, Gauer T, Hofmann C
STRAHLENTHER ONKOL. 2023;199(7):686-691.
Novel hybrid treatment planning approach for irradiation a pediatric craniospinal axis
Ziemann C, Cremers F, Motisi L, Albers D, MacPherson M, Rades D
MED DOSIM. 2023;49(2):93-101.
Salvage Chemotherapy with Cisplatin, Ifosfamide, and Paclitaxel in Aggressive Variant of Metastatic Castration-Resistant Prostate Cancer
Amsberg G, Zilles M, Mansour W, Gild P, Alsdorf W, Kaune M, Böckelmann L, Hauschild J, Krisp C, Rohlfing T, Saygi C, Alawi M, Zielinski A, Langebrake C, Su X, Perner S, Tilki D, Schluter H, Graefen M, Dyshlovoy S, Bokemeyer C
INT J MOL SCI. 2022;23(23):.
DEGRO practical guideline for central nervous system radiation necrosis part 2: treatment
Bernhardt D, König L, Grosu A, Rieken S, Krieg S, Wick W, Wiestler B, Schmidt-Graf F, Sahm F, Gempt J, Meyer B, Krause B, Petersen C, Fietkau R, Thomas M, Giordano F, Wittig-Sauerwein A, Debus J, Tabatabai G, Hau P, Steinbach J, Combs S
STRAHLENTHER ONKOL. 2022;198(11):971-980.
DEGRO practical guideline for central nervous system radiation necrosis part 1: classification and a multistep approach for diagnosis
Bernhardt D, König L, Grosu A, Wiestler B, Rieken S, Wick W, Gempt J, Krieg S, Schmidt-Graf F, Sahm F, Meyer B, Krause B, Petersen C, Fietkau R, Thomas M, Giordano F, Wittig-Sauerwein A, Debus J, Tabatabai G, Hau P, Steinbach J, Combs S
STRAHLENTHER ONKOL. 2022;198(10):873-883.
Treatment in Latent Tuberculosis Uveitis-Is Immunosuppression Effective or Is Conventional 3- or 4-Drug Antituberculosis Therapy Mandatory?
Bigdon E, Steinhorst N, Weissleder S, Durchkiv V, Stübiger N
J CLIN MED. 2022;11(9):.
Tissue Microarray Analyses Suggest Axl as a Predictive Biomarker in HPV-Negative Head and Neck Cancer
Busch C, Hagel C, Becker B, Oetting A, Möckelmann N, Droste C, Möller-Koop C, Witt M, Blaurock M, Loges S, Rothkamm K, Betz C, Münscher A, Clauditz T, Rieckmann T
CANCERS. 2022;14(7):.
Detection of stage I HPV-driven oropharyngeal cancer in asymptomatic individuals in the Hamburg City Health Study using HPV16 E6 serology - A proof-of-concept study
Busch C, Hoffmann A, Viarisio D, Becker B, Rieckmann T, Betz C, Bender N, Schroeder L, Hussein Y, Petersen E, Jagodzinski A, Schäfer I, Burandt E, Lang Kuhs K, Pawlita M, Waterboer T, Brenner N
ECLINICALMEDICINE. 2022;53:.
Multi-center planning study of radiosurgery for intracranial metastases through Automation (MC-PRIMA) by crowdsourcing prior web-based plan challenge study
Chan M, Gevaert T, Kadoya N, Dorr J, Leung R, Alheet S, Toutaoui A, Farias R, Wong M, Skourou C, Valenti M, Farré I, Otero-Martínez C, O'Doherty D, Waldron J, Hanvey S, Grohmann M, Liu H
PHYS MEDICA. 2022;95:73-82.
Partial Reduction in BRCA1 Gene Dose Modulates DNA Replication Stress Level and Thereby Contributes to Sensitivity or Resistance
Classen S, Rahlf E, Jungwirth J, Albers N, Hebestreit L, Zielinski A, Poole L, Groth M, Koch P, Liehr T, Kankel S, Cordes N, Petersen C, Rothkamm K, Pospiech H, Borgmann K
INT J MOL SCI. 2022;23(21):.
Integration of radiation oncology teaching in medical studies by German medical faculties due to the new licensing regulations: An overview and recommendations of the consortium academic radiation oncology of the German Society for Radiation Oncology (DEGRO)
Dapper H, Belka C, Bock F, Budach V, Budach W, Christiansen H, Debus J, Distel L, Dunst J, Eckert F, Eich H, Eicheler W, Engenhart-Cabillic R, Fietkau R, Fleischmann D, Frerker B, Giordano F, Grosu A, Herfarth K, Hildebrandt G, Kaul D, Kölbl O, Krause M, Krug D, Martin D, Matuschek C, Medenwald D, Nicolay N, Niewald M, Oertel M, Petersen C, Pohl F, Raabe A, Rödel C, Rübe C, Schmalz C, Schmeel L, Steinmann D, Stüben G, Thamm R, Vordermark D, Vorwerk H, Wiegel T, Zips D, Combs S
STRAHLENTHER ONKOL. 2022;198(1):1-11.
Types of deviation and review criteria in pretreatment central quality control of tumor bed boost in medulloblastoma-an analysis of the German Radiotherapy Quality Control Panel in the SIOP PNET5 MB trial
Dietzsch S, Braesigk A, Seidel C, Remmele J, Kitzing R, Schlender T, Mynarek M, Geismar D, Jablonska K, Schwarz R, Pazos M, Weber D, Frick S, Gurtner K, Matuschek C, Harrabi S, Glück A, Lewitzki V, Dieckmann K, Benesch M, Gerber N, Obrecht D, Rutkowski S, Timmermann B, Kortmann R
STRAHLENTHER ONKOL. 2022;198(3):282-290.
Cytotoxic N-Methylpretrichodermamide B Reveals Anticancer Activity and Inhibits P-Glycoprotein in Drug-Resistant Prostate Cancer Cells
Dyshlovoy S, Busenbender T, Hauschild J, Girich E, Kriegs M, Hoffer K, Graefen M, Yurchenko A, Bokemeyer C, Amsberg G
MAR DRUGS. 2022;20(10):.
Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas
Goschzik T, Mynarek M, Doerner E, Schenk A, Spier I, Warmuth-Metz M, Bison B, Obrecht D, Struve N, Kortmann R, Schmid M, Aretz S, Rutkowski S, Pietsch T
ACTA NEUROPATHOL. 2022;144(6):1143-1156.
A Lack of Effectiveness in the ATM-Orchestrated DNA Damage Response Contributes to the DNA Repair Defect of HPV-Positive Head and Neck Cancer Cells
Köcher S, Zech H, Krug L, Gatzemeier F, Christiansen S, Meyer F, Rietow R, Struve N, Mansour W, Kriegs M, Petersen C, Betz C, Rothkamm K, Rieckmann T
FRONT ONCOL. 2022;12:.
In-situ x-ray fluorescence imaging of the endogenous iodine distribution in murine thyroids
Körnig C, Staufer T, Schmutzler O, Bedke T, Machicote A, Liu B, Liu Y, Gargioni E, Feliu N, Parak W, Huber S, Grüner F
SCI REP-UK. 2022;12(1):2903.
The dogma of Cetuximab and Radiotherapy in head and neck cancer - A dawn to dusk journey
Krishnamurthy S, Ahmed I, Bhise R, Mohanti B, Sharma A, Rieckmann T, Paterson C, Bonomo P
CLIN TRANSL RAD ONCO. 2022;34:75-81.
Quality of life, HPV-status and phase angle predict survival in head and neck cancer patients under (chemo)radiotherapy undergoing nutritional intervention: Results from the prospective randomized HEADNUT-trial
Kutz L, Abel J, Schweizer D, Tribius S, Krüll A, Petersen C, Löser A
RADIOTHER ONCOL. 2022;166:145-153.
Combined Liquid Biopsy Methylation Analysis of CADM1 and MAL in Cervical Cancer Patients
Leffers M, Herbst J, Kropidlowski J, Prieske K, Bohnen A, Peine S, Jaeger A, Prieske K, Goy Y, Schmalfeldt B, Pantel K, Wölber L, Effenberger K, Wikman H
CANCERS. 2022;14(16):.
Nutritional Status Impacts Quality of Life in Head and Neck Cancer Patients Undergoing (Chemo)Radiotherapy: Results from the Prospective HEADNUT Trial
Löser A, Avanesov M, Thieme A, Gargioni E, Baehr A, Hintelmann K, Tribius S, Krüll A, Petersen C
NUTR CANCER. 2022;74(8):2887-2895.
Impact of dosimetric factors on long-term percutaneous enteral gastrostomy (PEG) tube dependence in head and neck cancer patients after (chemo)radiotherapy-results from a prospective randomized trial
Löser A, Grohmann M, Finger A, Greinert F, Krause L, Molwitz I, Krüll A, Petersen C
STRAHLENTHER ONKOL. 2022;198(11):1016-1024.
Correction to: The impact of nutritional counseling on thyroid disorders in head and neck cancer patients after (chemo)radiotherapy: results from a prospective interventional trial
Löser A, Ramke K, Grohmann M, Krause L, Roser P, Greinert F, Finger A, Sommer M, Culmann E, Lorenz T, Becker S, Henze M, Schodrok D, von Grundherr J, Tribius S, Krüll A, Petersen C
STRAHLENTHER ONKOL. 2022;198(2):149.
The impact of nutritional counseling on thyroid disorders in head and neck cancer patients after (chemo)radiotherapy: results from a prospective interventional trial
Löser A, Ramke K, Grohmann M, Krause L, Roser P, Greinert F, Finger A, Sommer M, Culmann E, Lorenz T, Becker S, Henze M, Schodrok D, von Grundherr J, Tribius S, Krüll A, Petersen C
STRAHLENTHER ONKOL. 2022;198(2):135-148.
Classical and disease-specific quality indicators in glioma surgery-Development of a quality checklist to improve treatment quality in glioma patients
Menke C, Lohmann S, Baehr A, Grauer O, Holling M, Brokinkel B, Schwake M, Stummer W, Schipmann S
NEURO-ONCOL PRACT. 2022;9(1):59-67.
Efficient DNA repair mitigates replication stress resulting in less immunogenic cytosolic DNA in radioresistant breast cancer stem cells
Meyer F, Engel A, Krause A, Wagner T, Poole L, Dubrovska A, Peitzsch C, Rothkamm K, Petersen C, Borgmann K
FRONT IMMUNOL. 2022;13:765284.
Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism
Monteiro C, Miarka L, Perea-García M, Priego N, García-Gómez P, Álvaro-Espinosa L, de Pablos-Aragoneses A, Yebra N, Retana D, Baena P, Fustero-Torre C, Graña-Castro O, Troulé K, Caleiras E, Tezanos P, Muela P, Cintado E, Trejo J, Sepúlveda J, González-León P, Jiménez-Roldán L, Moreno L, Esteban O, Pérez-Núñez Á, Hernández-Lain A, Mazarico Gallego J, Ferrer I, Suárez R, Garrido-Martín E, Paz-Ares L, Dalmasso C, Cohen-Jonathan Moyal E, Siegfried A, Hegarty A, Keelan S, Varešlija D, Young L, Mohme M, Goy Y, Wikman H, Fernández-Alén J, Blasco G, Alcázar L, Cabañuz C, Grivennikov S, Ianus A, Shemesh N, Faria C, Lee R, Lorigan P, Le Rhun E, Weller M, Soffietti R, Bertero L, Ricardi U, Bosch-Barrera J, Sais E, Teixidor E, Hernández-Martínez A, Calvo A, Aristu J, Martin S, Gonzalez A, Adler O, Erez N, Valiente M
NAT MED. 2022;28(4):752-765.
Combined Targeting of AKT and mTOR Inhibits Tumor Formation of EpCAM+ and CD90+ Human Hepatocellular Carcinoma Cells in an Orthotopic Mouse Model
Moustafa M, Dähling K, Günther A, Riebandt L, Smit D, Riecken K, Schröder C, Zhuang R, Krech T, Kriegs M, Fehse B, Izbicki J, Fischer L, Nashan B, Li J, Jücker M
CANCERS. 2022;14(8):.
Planning Benchmark Study for Stereotactic Body Radiation Therapy of Liver Metastases: Results of the DEGRO/DGMP working group stereotactic radiotherapy and radiosurgery
Moustakis C, Blanck O, Chan M, Boda-Heggemann J, Andratschke N, Duma M, Albers D, Bäumer C, Fehr R, Körber S, Schmidhalter D, Alraun M, Baus W, Beckers E, Dierl M, Droege S, Ebrahimi Tazehmahalleh F, Fleckenstein J, Guckenberger M, Heinz C, Henkenberens C, Hennig A, Köhn J, Kornhuber C, Krieger T, Loutfi-Krauss B, Mayr M, Oechsner M, Pfeiler T, Pollul G, Schöffler J, Tümmler H, Ullm C, Walke M, Weigel R, Wertman M, Wiehle R, Wiezorek T, Wilke L, Wolf U, Eich H, Schmitt D
INT J RADIAT ONCOL. 2022;113(1):214-227.
Clinical and molecular characterization of isolated M1 disease in pediatric medulloblastoma: experience from the German HIT-MED studies
Obrecht D, Mynarek M, Hagel C, Kwiecien R, Spohn M, Bockmayr M, Bison B, Pfister S, Jones D, Sturm D, von Deimling A, Sahm F, von Hoff K, Juhnke B, Benesch M, Gerber N, Friedrich C, von Bueren A, Kortmann R, Schwarz R, Pietsch T, Fleischhack G, Schüller U, Rutkowski S
J NEURO-ONCOL. 2022;157(1):37-48.
Characterization and dynamics of the soluble immunological microenvironment in melanoma patients undergoing radiotherapy
Oertel M, Borrmann K, Baehr A, Eich H, Greve B
RADIAT ONCOL. 2022;17(1):.
DNA Methylation subclass Receptor Tyrosine Kinase II (RTK II) is predictive for seizure development in glioblastoma patients
Ricklefs F, Drexler R, Wollmann K, Eckhardt A, Heiland D, Sauvigny T, Maire C, Lamszus K, Westphal M, Schüller U, Dührsen L
NEURO-ONCOLOGY. 2022;24(11):1886-1897.
Monitoring very low dose radiation damage in DNA using "field-friendly" biomarkers
Rothkamm K, Burdak-Rothkamm S
2022. Biomarkers of Radiation in the Environment. Wood M, Mothersill C, Tsakanova G, Cresswell T, Woloschak G (Hrsg.). 1. Aufl. Dordrecht: Springer, 137-151.
The Microbeam Insert at the White Beam Beamline P61A at the Synchrotron PETRA III/DESY: A New Tool for High Dose Rate Irradiation Research
Schültke E, Fiedler S, Mewes C, Gargioni E, Klingenberg J, Abreu Faria G, Lerch M, Petasecca M, Prehn F, Wegner M, Scholz M, Jaekel F, Hildebrandt G
CANCERS. 2022;14(20):.
Increased replication stress and R-loop accumulation in EGFRvIII expressing glioblastoma present new therapeutic opportunities
Struve N, Hoffer K, Weik A, Riepen B, Krug L, Cetin M, Burmester J, Ott L, Liebing J, Gatzemeier F, Müller-Goebel J, Bußmann L, Parplys A, Unger K, Mansour W, Schüller U, Rieckmann T, Petersen C, Rothkamm K, Short S, Kriegs M
NEURO-ONCOL ADV. 2022;4(1):vdab180.
Dual PI3K/mTOR Inhibitor NVP-BEZ235 Leads to a Synergistic Enhancement of Cisplatin and Radiation in Both HPV-Negative and -Positive HNSCC Cell Lines
Subtil F, Gröbner C, Recknagel N, Parplys A, Kohl S, Arenz A, Eberle F, Dikomey E, Engenhart-Cabillic R, Schötz U
CANCERS. 2022;14(13):.
Myocardial injury detected by T1 and T2 mapping on CMR predicts subsequent cancer therapy-related cardiac dysfunction in patients with breast cancer treated by epirubicin-based chemotherapy or left-sided RT
Tahir E, Azar M, Shihada S, Seiffert K, Goy Y, Beitzen-Heineke A, Molwitz I, Muellerleile K, Stehning C, Schön G, Adam G, Petersen C, Müller V, Lund G
EUR RADIOL. 2022;32(3):1853-1865.
Novel preclinical gastroenteropancreatic neuroendocrine neoplasia models demonstrate the feasibility of mutation-based targeted therapy
Viol F, Sipos B, Fahl M, Clauditz T, Amin T, Kriegs M, Nieser M, Izbicki J, Huber S, Lohse A, Schrader J
CELL ONCOL. 2022;45(6):1401-1419.
Head and neck tumor cells treated with hypofractionated irradiation die via apoptosis and are better taken up by M1-like macrophages
Wedekind H, Walz K, Buchbender M, Rieckmann T, Strasser E, Grottker F, Fietkau R, Frey B, Gaipl U, Rückert M
STRAHLENTHER ONKOL. 2022;198(2):171-182.
Adjuvant radiotherapy and local recurrence in vulvar cancer - a subset analysis of the AGO-CaRE-1 study
Woelber L, Prieske K, Eulenburg C, Corradini S, Petersen C, Bommert M, Blankenstein T, Hilpert F, de Gregorio N, Iborra S, Sehouli J, Ignatov A, Hillemanns P, Fuerst S, Strauss H, Baumann K, Beckmann M, Mustea A, Mahner S, Jaeger A
GYNECOL ONCOL. 2022;164(1):68-75.
Patient derived ex vivo tissue slice cultures demonstrate a profound DNA double-strand break repair defect in HPV-positive oropharyngeal head and neck cancer
Zech H, Berger J, Mansour W, Nordquist L, von Bargen C, Bußmann L, Oetting A, Christiansen S, Möckelmann N, Böttcher A, Busch C, Petersen C, Betz C, Rothkamm K, Kriegs M, Köcher S, Rieckmann T
RADIOTHER ONCOL. 2022;168:138-146.
Targeting the DNA replication stress phenotype of KRAS mutant cancer cells
Al Zubaidi T, Gehrisch O, Genois M, Liu Q, Lu S, Kung J, Xie Y, Schuemann J, Lu H, Hata A, Zou L, Borgmann K, Willers H
SCI REP-UK. 2021;11(1):.
TP53 modulates radiotherapy fraction size sensitivity in normal and malignant cells
Anbalagan S, Ström C, Downs J, Jeggo P, McBay D, Wilkins A, Rothkamm K, Harrington K, Yarnold J, Somaiah N
SCI REP-UK. 2021;11(1):.
Kinomic comparison of snap frozen and ex vivo-cultured head and neck tumors
Berger J, Zech H, Hoffer K, von Bargen C, Nordquist L, Bussmann L, Gatzemeier F, Busch C, Möckelmann N, Münscher A, Betz C, Petersen C, Rothkamm K, Rieckmann T, Köcher S, Kriegs M
ORAL ONCOL. 2021;123:.
DNA Damage Response during Replication Correlates with CIN70 Score and Determines Survival in HNSCC Patients
Bold I, Specht A, Droste C, Zielinski A, Meyer F, Clauditz T, Münscher A, Werner S, Rothkamm K, Petersen C, Borgmann K
CANCERS. 2021;13(6):.
Molecular Mechanisms Associated with Brain Metastases in HER2-Positive and Triple Negative Breast Cancers
Bryan S, Witzel I, Borgmann K, Oliveira-Ferrer L
CANCERS. 2021;13(16):.
DNA Damage Repair Deficiency and Synthetic Lethality for Cancer Treatment
Burdak-Rothkamm S, Rothkamm K
TRENDS MOL MED. 2021;27(1):91-92.
Analyzing tyrosine kinase activity in head and neck cancer by functional kinomics: Identification of hyperactivated Src-family kinases as prognostic markers and potential targets
Bußmann L, Hoffer K, von Bargen C, Droste C, Lange T, Kemmling J, Schröder-Schwarz J, Vu A, Akingunsade L, Nollau P, Rangarajan S, de Wijn R, Oetting A, Müller C, Böckelmann L, Zech H, Berger J, Möckelmann N, Busch C, Böttcher A, Gatzemeier F, Klinghammer K, Simnica D, Binder M, Struve N, Rieckmann T, Schumacher U, Clauditz T, Betz C, Petersen C, Rothkamm K, Münscher A, Kriegs M
INT J CANCER. 2021;149(5):1166 - 1180.
Current status and developments of German curriculum-based residency training programmes in radiation oncology
Büttner M, Cordes N, Gauer T, Habermehl D, Klautke G, Micke O, Mäurer M, Sokoll J, Troost E, Christiansen H, Niyazi M
RADIAT ONCOL. 2021;16(1):.
Pretreatment central quality control for craniospinal irradiation in non-metastatic medulloblastoma: First experiences of the German radiotherapy quality control panel in the SIOP PNET5 MB trial
Dietzsch S, Braesigk A, Seidel C, Remmele J, Kitzing R, Schlender T, Mynarek M, Geismar D, Jablonska K, Schwarz R, Pazos M, Walser M, Frick S, Gurtner K, Matuschek C, Harrabi S, Glück A, Lewitzki V, Dieckmann K, Benesch M, Gerber N, Rutkowski S, Timmermann B, Kortmann R
STRAHLENTHER ONKOL. 2021;197(8):674-682.
Ewing sarcoma
Eaton B, Claude L, Indelicato D, Vatner R, Yeh B, Schwarz R, Laack N
PEDIATR BLOOD CANCER. 2021;68(S2):.
Osteosarcoma
Eaton B, Schwarz R, Vatner R, Yeh B, Claude L, Indelicato D, Laack N
PEDIATR BLOOD CANCER. 2021;68(S2):.
Emerging Insights into Keratin 16 Expression during Metastatic Progression of Breast Cancer
Elazezy M, Schwentesius S, Stegat L, Wikman H, Werner S, Mansour W, Failla A, Peine S, Müller V, Thiery J, Ebrahimi Warkiani M, Pantel K, Joosse S
CANCERS. 2021;13(15):.
Der Einfluss von intrafraktioneller Patientenbewegung auf die Behandlungsgenauigkeit bei Radiochirurgie multipler Hirnmetastasen: Abstracts DEGRO 2021
Grohmann M, Todorovic M, Petersen C
STRAHLENTHER ONKOL. 2021;197((Suppl 1)):S51-S52.
Dual Inhibition of PARP and the Intra-S/G2 Cell Cycle Checkpoints Results in Highly Effective Radiosensitization of HPV-Positive HNSCC Cells
Hintelmann K, Berenz T, Kriegs M, Christiansen S, Gatzemeier F, Struve N, Petersen C, Betz C, Rothkamm K, Oetting A, Rieckmann T
FRONT ONCOL. 2021;11:683688.
Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFβ/CTGF Axis
Hinz N, Baranowsky A, Horn M, Kriegs M, Sibbertsen F, Smit D, Clezardin P, Lange T, Schinke T, Jücker M
CELLS-BASEL. 2021;10(2):.
Late Sequelae of Radiotherapy: The Effect of Technical and Conceptual Innovations in Radiation Oncology
Hoeller U, Borgmann K, Oertel M, Haverkamp U, Budach V, Eich H
DTSCH ARZTEBL INT. 2021;118(12):205-211.
Outcome in dedifferentiated chondrosarcoma for patients treated with multimodal therapy: Results from the EUROpean Bone Over 40 Sarcoma Study
Hompland I, Ferrari S, Bielack S, Palmerini E, Hall K, Picci P, Hecker-Nolting S, Donati D, Blattmann C, Bjerkehagen B, Staals E, Kager L, Gambarotti M, Kühne T, Eriksson M, Ferraresi V, Kevric M, Biagini R, Baumhoer D, Brosjø O, Comandone A, Schwarz R, Bertulli R, Kessler T, Hansson L, Apice G, Heydrich B, Setola E, Flörcken A, Ruggieri P, Krasniqi F, Hofmann-Wackersreuther G, Casali P, Reichardt P, Smeland S
EUR J CANCER. 2021;151:150-158.
Feasibility of Monitoring Tumor Response by Tracking Nanoparticle-Labelled T Cells Using X-ray Fluorescence Imaging-A Numerical Study
Kahl H, Staufer T, Körnig C, Schmutzler O, Rothkamm K, Grüner F
INT J MOL SCI. 2021;22(16):.
Peer review analysis in the field of radiation oncology: results from a web-based survey of the Young DEGRO working group
Käsmann L, Schröder A, Frey B, Fleischmann D, Gauer T, Ebert N, Hecht M, Krug D, Niyazi M, Mäurer M
STRAHLENTHER ONKOL. 2021;197(8):667-673.
Fully automated counting of DNA damage foci in tumor cell culture: A matter of cell separation
Köcher S, Volquardsen J, Perugachi Heinsohn A, Petersen C, Roggenbuck D, Rothkamm K, Mansour W
DNA REPAIR. 2021;102:.
Carbon fiber-reinforced PEEK versus titanium implants - an in vitro comparison of susceptibility artifacts in CT and MR imaging
Krätzig T, Mende K, Mohme M, Kniep H, Dreimann M, Stangenberg M, Westphal M, Gauer T, Eicker S
NEUROSURG REV. 2021;44(4):2163-2170.
Correction to: Innovative radiation oncology Together-Precise, Personalized, Human
Krug D, Hecht M, Ebert N, Mäurer M, Fleischmann D, Fokas E, Straube C, Nicolay N, Hörner-Rieber J, Schmitt D, von Neubeck C, Zamboglou C, Sperk E, Kaul D, Hess J, Corradini S, Seidel C, Gani C, Baues C, Frey B, Blanck O, Gauer T, Niyazi M
STRAHLENTHER ONKOL. 2021;197(12):1049-1050.
Innovative radiation oncology Together - Precise, Personalized, Human: Vision 2030 for radiotherapy & radiation oncology in Germany
Krug D, Hecht M, Ebert N, Mäurer M, Fleischmann D, Fokas E, Straube C, Nicolay N, Hörner-Rieber J, Schmitt D, von Neubeck C, Zamboglou C, Sperk E, Kaul D, Heß-Rieger J, Corradini S, Seidel C, Gani C, Baues C, Frey B, Blanck O, Gauer T, Niyazi M
STRAHLENTHER ONKOL. 2021;197(12):1043-1048.
Head and neck cancer patients under (chemo-)radiotherapy undergoing nutritional intervention: Results from the prospective randomized HEADNUT-trial
Löser A, Abel J, Kutz L, Krause L, Finger A, Greinert F, Sommer M, Lorenz T, Culmann E, von Grundherr J, Wegert L, Lehmann L, Matnjani G, Schwarz R, Brackrock S, Krüll A, Petersen C, Carl C
RADIOTHER ONCOL. 2021;159:82-90.
DIAPH1 regulates chromosomal instability of cancer cells by controlling microtubule dynamics
Miao S, Schäfer P, Nojszewski J, Meyer F, Windhorst S
EUR J CELL BIOL. 2021;100(3):.
P02.01 A strategy to personalize the use of radiation in patients with brain metastasis based on S100A9-mediated resistance
Miarka L, Monteiro C, Dalmasso C, Yebra N, Fustero-Torre C, Hegarty A, Keelan S, Goy Y, Mohme M, Caleiras E, Vareslija D, Young L, Soffietti R, Fernández-Alén J, Blasco G, Alcázar L, Sepúlveda J, Pérez A, Lain A, Siegfried A, Wikman H, Cohen-Jonathan Moyal E, Valiente M
NEURO-ONCOLOGY. 2021;23(Supplement_2):ii17-ii17.
Interplay between DNA replication stress, chromatin dynamics and DNA-damage response for the maintenance of genome stability
Mognato M, Burdak-Rothkamm S, Rothkamm K
MUTAT RES-REV MUTAT. 2021;787:.
Oct4 confers stemness and radioresistance to head and neck squamous cell carcinoma by regulating the homologous recombination factors PSMC3IP and RAD54L
Nathansen J, Lukiyanchuk V, Hein L, Stolte M, Borgmann K, Löck S, Kurth I, Baumann M, Krause M, Linge A, Dubrovska A
ONCOGENE. 2021;40(24):4214-4228.
Beyond the Double-Strand Breaks: The Role of DNA Repair Proteins in Cancer Stem-Cell Regulation
Nathansen J, Meyer F, Müller L, Schmitz M, Borgmann K, Dubrovska A
CANCERS. 2021;13(19):.
Investigating the impact of long term exposure to chemical agents on the chromosomal radiosensitivity using human lymphoblastoid GM1899A cells
Nuta O, Bouffler S, Lloyd D, Ainsbury E, Sepai O, Rothkamm K
SCI REP-UK. 2021;11(1):.
Correction to: Prognostic impact of gross tumor volume during radical radiochemotherapy of locally advanced non-small cell lung cancer-results from the NCT03055715 multicenter cohort study of the Young DEGRO Trial Group
Ostheimer C, Mäurer M, Ebert N, Schmitt D, Krug D, Baumann R, Henkenberens C, Giordano F, Sautter L, López G, Fleischmann D, Niyazi M, Käsmann L, Kaul D, Thieme A, Billiet C, Dobiasch S, Arnold C, Oertel M, Haussmann J, Gauer T, Goy Y, Suess C, Ziegler S, Panje C, Baues C, Trommer M, Skripcak T, Medenwald D
STRAHLENTHER ONKOL. 2021;197(6):560-561.
Prognostic impact of gross tumor volume during radical radiochemotherapy of locally advanced non-small cell lung cancer-results from the NCT03055715 multicenter cohort study of the Young DEGRO Trial Group
Ostheimer C, Mäurer M, Ebert N, Schmitt D, Krug D, Baumann R, Henkenberens C, Giordano F, Sautter L, López G, Fleischmann D, Niyazi M, Käsmann L, Kaul D, Thieme A, Billiet C, Dobiasch S, Arnold C, Oertel M, Haussmann J, Gauer T, Goy Y, Suess C, Ziegler S, Panje C, Baues C, Trommer-Nestler M, Skripcak T, Medenwald D
STRAHLENTHER ONKOL. 2021;197(5):385-395.
X-ray-Based Techniques to Study the Nano-Bio Interface
Sanchez-Cano C, Alvarez-Puebla R, Abendroth J, Beck T, Blick R, Cao Y, Caruso F, Chakraborty I, Chapman H, Chen C, Cohen B, Conceição A, Cormode D, Cui D, Dawson K, Falkenberg G, Fan C, Feliu N, Gao M, Gargioni E, Glüer C, Grüner F, Hassan M, Hu Y, Huang Y, Huber S, Huse N, Kang Y, Khademhosseini A, Keller T, Körnig C, Kotov N, Koziej D, Liang X, Liu B, Liu S, Liu Y, Liu Z, Liz-Marzán L, Ma X, Machicote A, Maison W, Mancuso A, Megahed S, Nickel B, Otto F, Palencia C, Pascarelli S, Pearson A, Peñate-Medina O, Qi B, Rädler J, Richardson J, Rosenhahn A, Rothkamm K, Rübhausen M, Sanyal M, Schaak R, Schlemmer H, Schmidt M, Schmutzler O, Schotten T, Schulz F, Sood A, Spiers K, Staufer T, Stemer D, Stierle A, Sun X, Tsakanova G, Weiss P, Weller H, Westermeier F, Xu M, Yan H, Zeng Y, Zhao Y, Zhao Y, Zhu D, Zhu Y, Parak W
ACS NANO. 2021;15(3):3754-3807.
X-ray Fluorescence Uptake Measurement of Functionalized Gold Nanoparticles in Tumor Cell Microsamples
Schmutzler O, Graf S, Behm N, Mansour W, Blumendorf F, Staufer T, Körnig C, Salah D, Kang Y, Peters J, Liu Y, Feliu N, Parak W, Burkhardt A, Gargioni E, Gennis S, Chandralingam S, Höeg F, Maison W, Rothkamm K, Schulz F, Grüner F
INT J MOL SCI. 2021;22(7):3691.
Parotid sparing and quality of life in long-term survivors of locally advanced head and neck cancer after intensity-modulated radiation therapy
Tribius S, Haladyn S, Hanken H, Busch C, Krüll A, Petersen C, Bergelt C
STRAHLENTHER ONKOL. 2021;197(3):219-230.
X-ray-Fluorescence Imaging for In Vivo Detection of Gold-Nanoparticle-Labeled Immune Cells: A GEANT4 Based Feasibility Study
Ungerer A, Staufer T, Schmutzler O, Körnig C, Rothkamm K, Grüner F
CANCERS. 2021;13(22):.
Einsatzmöglichkeiten der additiven Fertigung in der Herstellung von Phantomen
Wegner M, Gargioni E, Krause D
2021. Konstruktion für die Additive Fertigung 2020. Lachmayer R, Rettschlag K, Kaierle S (Hrsg.). 1. Aufl. Springer Spektrum, Berlin, Heidelberg, 267-282.
Indirectly additive manufactured deformable bladder model for a pelvic radiotherapy phantom
Wegner M, Gargioni E, Krause D
Transactions on Additive Manufacturing Meets Medicine. 2021;3(1):.
Comparison of intelligent 4D CT sequence scanning and conventional spiral 4D CT: a first comprehensive phantom study
Werner R, Szkitsak J, Sentker T, Madesta F, Schwarz A, Fernolendt S, Vornehm M, Gauer T, Bert C, Hofmann C
PHYS MED BIOL. 2021;66(1):.
Improving interinstitutional and intertechnology consistency of pulmonary SBRT by dose prescription to the mean internal target volume dose
Wilke L, Moustakis C, Blanck O, Albers D, Albrecht C, Avcu Y, Boucenna R, Buchauer K, Etzelstorfer T, Henkenberens C, Jeller D, Jurianz K, Kornhuber C, Kretschmer M, Lotze S, Pemler P, Riegler A, Röser A, Schmidhalter D, Spruijt K, Surber G, Vallet V, Wiehle R, Willner J, Winkler P, Wittig A, Guckenberger M, Tanadini-Lang S
STRAHLENTHER ONKOL. 2021;197(9):836-846.
DNA Damage Repair Deficiency in Prostate Cancer
Burdak-Rothkamm S, Mansour W, Rothkamm K
TRENDS CANCER. 2020;6(11):974-984.
Establishment of a Transformation Coupled in vitro End Joining Assay to Estimate Radiosensitivity in Tumor Cells
Degenhardt S, Dreffke K, Schötz U, Petersen C, Engenhart-Cabillic R, Rothkamm K, Dahm-Daphi J, Dikomey E, Mansour W
FRONT ONCOL. 2020;10:1480.
The Intermediate Filament Synemin Regulates Non-Homologous End Joining in an ATM-Dependent Manner
Deville S, Vehlow A, Förster S, Dickreuter E, Borgmann K, Cordes N
CANCERS. 2020;12(7):.
Evaluation of Prognostic Factors and Role of Participation in a Randomized Trial or a Prospective Registry in Pediatric and Adolescent Nonmetastatic Medulloblastoma - A Report From the HIT 2000 Trial
Dietzsch S, Placzek F, Pietschmann K, von Bueren A, Matuschek C, Glück A, Guckenberger M, Budach V, Welzel J, Pöttgen C, Schmidberger H, Heinzelmann F, Paulsen F, Escudero M, Schwarz R, Hornung D, Martini C, Grosu A, Stueben G, Jablonska K, Dunst J, Stranzl-Lawatsch H, Dieckmann K, Timmermann B, Pietsch T, Warmuth-Metz M, Bison B, Kwiecien R, Benesch M, Gerber N, Grotzer M, Pfister S, Clifford S, von Hoff K, Klagges S, Rutkowski S, Kortmann R, Mynarek M
ADV RADIAT ONCOL. 2020;5(6):1158-1169.
Efficacy and Mechanism of Action of Marine Alkaloid 3,10-Dibromofascaplysin in Drug-Resistant Prostate Cancer Cells
Dyshlovoy S, Kaune M, Hauschild J, Kriegs M, Hoffer K, Busenbender T, Smirnova P, Zhidkov M, Poverennaya E, Oh-Hohenhorst S, Spirin P, Prassolov V, Tilki D, Bokemeyer C, Graefen M, von Amsberg G
MAR DRUGS. 2020;18(12):.
Marine alkaloid monanchoxymycalin C: a new specific activator of JNK1/2 kinase with anticancer properties
Dyshlovoy S, Kaune M, Kriegs M, Hauschild J, Busenbender T, Shubina L, Makarieva T, Hoffer K, Bokemeyer C, Graefen M, Stonik V, von Amsberg G
SCI REP-UK. 2020;10(1):13178.
Second-Generation Antiandrogen Therapy Radiosensitizes Prostate Cancer Regardless of Castration State through Inhibition of DNA Double Strand Break Repair
Elsesy M, Oh-Hohenhorst S, Löser A, Oing C, Mutiara S, Köcher S, Meien S, Zielinski A, Burdak-Rothkamm S, Tilki D, Huland H, Schwarz R, Petersen C, Bokemeyer C, Rothkamm K, Mansour W
CANCERS. 2020;12(9):.
Implementation analysis of patient reported outcomes (PROs) in oncological routine care: an observational study protocol
Görlach M, Schrage T, Bokemeyer C, Kröger N, Müller V, Petersen C, Betz C, Krüll A, Schulz H, Bleich C
HEALTH QUAL LIFE OUT. 2020;18(1):3.
Definition and quality requirements for stereotactic radiotherapy: consensus statement from the DEGRO/DGMP Working Group Stereotactic Radiotherapy and Radiosurgery
Guckenberger M, Baus W, Blanck O, Combs S, Debus J, Engenhart-Cabillic R, Gauer T, Grosu A, Schmitt D, Tanadini-Lang S, Moustakis C
STRAHLENTHER ONKOL. 2020;196(5):417-420.
Photoswitchable Azo- and Diazocine-Functionalized Derivatives of the VEGFR-2 Inhibitor Axitinib
Heintze L, Schmidt D, Rodat T, Witt L, Ewert J, Kriegs M, Herges R, Peifer C
INT J MOL SCI. 2020;21(23):.
Improving the Efficacy of Tumor Radiosensitization Through Combined Molecular Targeting
Hintelmann K, Kriegs M, Rothkamm K, Rieckmann T
FRONT ONCOL. 2020;10:1260.
Cerebral metastasis in recurrent squamous cell carcinoma of the vulva: case report and review of the literature
Jaeger A, Biermann M, Prieske K, Grimm D, Grottke A, Salamon J, Petersen C, Mueller V, Schmalfeldt B, Woelber L
ARCH GYNECOL OBSTET. 2020;301(2):327-332.
Proton Beam Therapy for Children With Neuroblastoma: Experiences From the Prospective KiProReg Registry
Jazmati D, Butzer S, Hero B, Ahmad Khalil D, Merta J, Bäumer C, Plum G, Fuchs J, Koerber F, Steinmeier T, Peters S, Doyen J, Thole T, Schmidt M, Blase C, Tippelt S, Eggert A, Schwarz R, Simon T, Timmermann B
FRONT ONCOL. 2020;10:617506.
The POLD1R689W variant increases the sensitivity of colorectal cancer cells to ATR and CHK1 inhibitors
Job A, Tatura M, Schäfer C, Lutz V, Schneider H, Lankat-Buttgereit B, Zielinski A, Borgmann K, Bauer C, Gress T, Buchholz M, Gallmeier E
SCI REP-UK. 2020;10(1):18924.
A novel workflow for three-dimensional analysis of tumour cell migration
Ketchen S, Rohwedder A, Knipp S, Esteves F, Struve N, Peckham M, Ladbury J, Curd A, Short S, Brüning-Richardson A
INTERFACE FOCUS. 2020;10(2):20190070.
Impact of Adherence to Multidisciplinary Recommendations for Adjuvant Treatment in Radical Prostatectomy Patients With High Risk of Recurrence
Knipper S, Sadat-Khonsari M, Boehm K, Mandel P, Budäus L, Steuber T, Maurer T, Heinzer H, Schwarz R, Sauter G, Tilki D, Huland H, Graefen M
CLIN GENITOURIN CANC. 2020;18(2):e112-e121.
Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity
Koch C, Kuske A, Joosse S, Yigit G, Sflomos G, Thaler S, Smit D, Werner S, Borgmann K, Gärtner S, Mossahebi Mohammadi P, Battista L, Cayrefourcq L, Altmüller J, Salinas-Riester G, Raithatha K, Zibat A, Goy Y, Ott L, Bartkowiak K, Tan T, Zhou Q, Speicher M, Müller V, Gorges T, Jücker M, Thiery J, Brisken C, Riethdorf S, Alix-Panabières C, Pantel K
EMBO MOL MED. 2020;12(9):.
HPV-positive HNSCC cell lines show strongly enhanced radiosensitivity after photon but not after carbon ion irradiation
Lerch S, Berthold S, Ziemann F, Dreffke K, Subtil F, Senger Y, Jensen A, Engenhart-Cabillic R, Dikomey E, Wittig A, Eberle F, Schötz U
RADIOTHER ONCOL. 2020;151:134-140.
Efficacy of HDAC Inhibitors Belinostat and Panobinostat against Cisplatin-Sensitive and Cisplatin-Resistant Testicular Germ Cell Tumors
Lobo J, Guimarães-Teixeira C, Barros-Silva D, Miranda-Gonçalves V, Camilo V, Guimarães R, Cantante M, Braga I, Maurício J, Oing C, Honecker F, Nettersheim D, Looijenga L, Henrique R, Jerónimo C
CANCERS. 2020;12(10):.
Activation of Epidermal Growth Factor Receptor Sensitizes Glioblastoma Cells to Hypoxia-Induced Cell Death
Luger A, Lorenz N, Urban H, Divé I, Engel A, Strassheimer F, Dettmer K, Zeiner P, Shaid S, Struve N, Kriegs M, Hofmann U, Oefner P, Harter P, Steinbach J, Ronellenfitsch M
CANCERS. 2020;12(8):.
Self-contained deep learning-based boosting of 4D cone-beam CT reconstruction
Madesta F, Sentker T, Gauer T, Werner R
MED PHYS. 2020;47(11):5619-5631.
Prevention of DNA Replication Stress by CHK1 Leads to Chemoresistance Despite a DNA Repair Defect in Homologous Recombination in Breast Cancer
Meyer F, Becker S, Classen S, Parplys A, Mansour W, Riepen B, Timm S, Ruebe C, Jasin M, Wikman H, Petersen C, Rothkamm K, Borgmann K
CELLS-BASEL. 2020;9(1):.
Influence of radiation dose to pharyngeal constrictor muscles on late dysphagia and quality of life in patients with locally advanced oropharyngeal carcinoma
Mogadas S, Busch C, Pflug C, Hanken H, Krüll A, Petersen C, Tribius S
STRAHLENTHER ONKOL. 2020;196(6):522-529.
Radiation Biomarkers in Large Scale Human Health Effects Studies
Moquet J, Rothkamm K, Barnard S, Ainsbury E
J PERS MED. 2020;10(4):.
The Role of Telomerase in Radiation-Induced Genomic Instability
Nuta O, Rothkamm K, Darroudi F
RADIAT RES. 2020;193(5):451-459.
Ablative Bestrahlung bei Patientinnen mit metastasiertem Mammakarzinom
Petersen C, Löser A
ONKOLOGE. 2020;26(6):524-529.
Radiochemotherapy with or without cetuximab for unresectable esophageal cancer: final results of a randomized phase 2 trial (LEOPARD-2)
Rades D, Bartscht T, Hunold P, Schmidberger H, König L, Debus J, Belka C, Homann N, Spillner P, Petersen C, Kuhnt T, Fietkau R, Ridwelski K, Karcher-Kilian K, Kranich A, Männikkö S, Schild S, Maderer A, Moehler M
STRAHLENTHER ONKOL. 2020;196(9):795-804.
Exploiting Chromosomal Instability of PTEN-Deficient Triple-Negative Breast Cancer Cell Lines for the Sensitization against PARP1 Inhibition in a Replication-Dependent Manner
Rieckhoff J, Meyer F, Classen S, Zielinski A, Riepen B, Wikman H, Petersen C, Rothkamm K, Borgmann K, Parplys A
CANCERS. 2020;12(10):.
Radiosensitisation and enhanced tumour growth delay of colorectal cancer cells by sustained treatment with trifluridine/tipiracil and X-rays
Rothkamm K, Christiansen S, Rieckmann T, Horn M, Frenzel T, Brinker A, Schumacher U, Stein A, Petersen C, Burdak-Rothkamm S
CANCER LETT. 2020;493:179-188.
Technological quality requirements for stereotactic radiotherapy: Expert review group consensus from the DGMP Working Group for Physics and Technology in Stereotactic Radiotherapy
Schmitt D, Blanck O, Gauer T, Fix M, Brunner T, Fleckenstein J, Loutfi-Krauss B, Manser P, Werner R, Wilhelm M, Baus W, Moustakis C
STRAHLENTHER ONKOL. 2020;196(5):421-443.
Dual PI3K/mTOR Inhibitor NVP-BEZ235 Enhances Radiosensitivity of Head and Neck Squamous Cell Carcinoma (HNSCC) Cell Lines Due to Suppressed Double-Strand Break (DSB) Repair by Non-Homologous End Joining
Schötz U, Balzer V, Brandt F, Ziemann F, Subtil F, Rieckmann T, Köcher S, Engenhart-Cabillic R, Dikomey E, Wittig A, Arenz A
CANCERS. 2020;12(2):.
Development of a Short Instrument for Measuring Health-Related Quality of Life in Oncological Patients for Clinical Use: Protocol for an Observational Study
Schrage T, Görlach M, Betz C, Bokemeyer C, Kröger N, Mueller V, Petersen C, Krüll A, Schulz H, Bleich C
JMIR RES PROTOC. 2020;9(7):e17854.
Roadmap for metal nanoparticles in radiation therapy. current status, translational challenges, and future directions
Schuemann J, Bagley A, Berbeco R, Bromma K, Butterworth K, Byrne H, Chithrani D, Cho S, Cook J, Favaudon V, Gholami Y, Gargioni E, Hainfeld J, Hespeels F, Heuskin A, Ibeh U, Kuncic Z, Kunjachan S, Lacombe S, Lucas S, Lux F, McMahon S, Nevozhay D, Ngwa W, Payne J, Penninckx S, Porcel E, Prise K, Rabus H, Ridwan S, Rudek B, Sanche L, Singh B, Smilowitz H, Sokolov K, Sridhar S, Stanishevskiy Y, Sung W, Tillement O, Virani N, Yantasee W, Krishnan S
PHYS MED BIOL. 2020;65(21):21RM02.
4D CT image artifacts affect local control in SBRT of lung and liver metastases
Sentker T, Schmidt V, Ozga A, Petersen C, Madesta F, Hofmann C, Werner R, Gauer T
RADIOTHER ONCOL. 2020;148:229-234.
Induction of DNA damage, apoptosis and cell cycle perturbation mediate cytotoxic activity of new 5-aminosalicylate-4-thiazolinone hybrid derivatives
S Ramadan W, Saleh E, Menon V, Vazhappilly C, Abdu-Allah H, El-Shorbagi A, Mansour W, El-Awady R
BIOMED PHARMACOTHER. 2020;131:110571.
EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma
Struve N, Binder Z, Stead L, Brend T, Bagley S, Faulkner C, Ott L, Müller-Goebel J, Weik A, Hoffer K, Krug L, Rieckmann T, Bußmann L, Henze M, Morrissette J, Kurian K, Schüller U, Petersen C, Rothkamm K, O Rourke D, Short S, Kriegs M
ONCOGENE. 2020;39(15):3041-3055.
Influence of 3D-printed collimator thickness on near-the-edge scattering of high-energy electrons
Stuchebrov S, Bulavskaya A, Cherepennikov Y, Gargioni E, Grigorieva A, Miloichikova I
J INSTRUM. 2020;15(04):C04023-C04023.
Prognostic factors for lymphedema in patients with locally advanced head and neck cancer after combined radio(chemo)therapy- results of a longitudinal study
Tribius S, Pazdyka H, Tennstedt P, Busch C, Hanken H, Krüll A, Petersen C
ORAL ONCOL. 2020;109:104856.
Experimental Determination of the Effective Dose from Dental CBCT Scans: Working Paper
Waschkewitz J, Buss C, Gargioni E, Scheifele C
2020.
Implications of SARS-CoV-2 Infection and COVID-19 Crisis on Clinical Cancer Care: Report of the University Cancer Center Hamburg: Report of the University Cancer Center Hamburg
Weisel K, Morgner-Miehlke A, Petersen C, Fiedler W, Block A, Schafhausen P, Knobloch J, Bokemeyer C
ONCOL RES TREAT. 2020;43(6):307-313.
Digital Health meets Hamburg integrated medical degree program iMED: Concept and introduction of the new interdisciplinary 2nd track Digital Health
Werner R, Henningsen M, Schmitz R, Guse A, Augustin M, Gauer T
GMS J MED EDU. 2020;37(6):Doc61.
Intelligent 4D CT sequence scanning (i4DCT): First scanner prototype implementation and phantom measurements of automated breathing signal-guided 4D CT
Werner R, Sentker T, Madesta F, Schwarz A, Vornehm M, Gauer T, Hofmann C
MED PHYS. 2020;47(6):2408-2412.
Mass Spectrometric Comparison of HPV-Positive and HPV-Negative Oropharyngeal Cancer
Wurlitzer M, Möckelmann N, Kriegs M, Vens M, Omidi M, Hoffer K, Bargen C, Möller-Koop C, Witt M, Droste C, Oetting A, Petersen H, Busch C, Münscher A, Schlüter H, Clauditz T, Rieckmann T
CANCERS. 2020;12(6):.
Current pharmacotherapy for testicular germ cell cancer
Alsdorf W, Seidel C, Bokemeyer C, Oing C
EXPERT OPIN PHARMACO. 2019;20(7):837-850.
HPV-negative and HPV-positive HNSCC cell lines show similar numerical but different structural chromosomal aberrations
Arenz A, Patze J, Kornmann E, Wilhelm J, Ziemann F, Wagner S, Wittig A, Schoetz U, Engenhart-Cabillic R, Dikomey E, Fritz B
HEAD NECK-J SCI SPEC. 2019;41(11):3869-3879.
Receptor tyrosine kinase MET as potential target of multi-kinase inhibitor and radiosensitizer sorafenib in HNSCC
Beizaei K, Gleißner L, Hoffer K, Bußmann L, Vu A, Steinmeister L, Laban S, Möckelmann N, Münscher A, Petersen C, Rothkamm K, Kriegs M
HEAD NECK-J SCI SPEC. 2019;41(1):208-215.
BRCA1 mislocalization leads to aberrant DNA damage response in heterozygous ABRAXAS1 mutation carrier cells
Bose M, Sachsenweger J, Laurila N, Parplys A, Willmann J, Jungwirth J, Groth M, Rapakko K, Nieminen P, Friedl T, Heiserich L, Meyer F, Tuppurainen H, Peltoketo H, Nevanlinna H, Pylkäs K, Borgmann K, Wiesmüller L, Winqvist R, Pospiech H
HUM MOL GENET. 2019;28(24):4148-4160.
Reduzierte strahleninduzierte Hirnnekrose bei Patienten mit Nasopharynxkarzinom durch Bevacizumab-Monotherapie
Carl C, Henze M
STRAHLENTHER ONKOL. 2019;195(3):277-280.
A common Chk1-dependent phenotype of DNA double-strand break suppression in two distinct radioresistant cancer types
Dinkelborg P, Wang M, Gheorghiu L, Gurski J, Hong T, Benes C, Juric D, Jimenez R, Borgmann K, Willers H
BREAST CANCER RES TR. 2019;174(3):605-613.
Radiation exposure by digital radiographic imaging in very low birth weight infants
Ebenebe C, Barreau C, Waschkewitz J, Schlattl H, Pinnschmidt H, Deindl P, Singer D, Herrmann J
J PERINATOL. 2019;39(1):115-119.
Results of a multicenter intensity modulated radiation therapy treatment planning comparison study for a sample prostate cancer case
Frenzel T, Albers D, Grohmann M, Krüll A
STRAHLENTHER ONKOL. 2019;195(10):913-922.
Clinical relevance of metal artefact reduction in computed tomography (iMAR) in the pelvic and head and neck region: Multi-institutional contouring study of gross tumour volumes and organs at risk on clinical cases
Hagen M, Kretschmer M, Würschmidt F, Gauer T, Giro C, Karsten E, Lorenzen J
J MED IMAG RADIAT ON. 2019;63(6):842-851.
Characterization of the Effects of Migrastatic Inhibitors on 3D Tumor Spheroid Invasion by High-resolution Confocal Microscopy
Harmer J, Struve N, Brüning-Richardson A
JOVE-J VIS EXP. 2019;(151):.
Comparative analysis between interstitial brachytherapy and stereotactic body irradiation for local ablation in liver malignancies
Hass P, Mohnike K, Kropf S, Brunner T, Walke M, Albers D, Petersen C, Damm R, Walter F, Ricke J, Powerski M, Corradini S
BRACHYTHERAPY. 2019;18(6):823-828.
Management of vertebral radiotherapy dose in paediatric patients with cancer: consensus recommendations from the SIOPE radiotherapy working group
Hoeben B, Carrie C, Timmermann B, Mandeville H, Gandola L, Dieckmann K, Ramos Albiac M, Magelssen H, Lassen-Ramshad Y, Ondrová B, Ajithkumar T, Alapetite C, Balgobind B, Bolle S, Cameron A, Davila Fajardo R, Dietzsch S, Dumont Lecomte D, van den Heuvel-Eibrink M, Kortmann R, Laprie A, Melchior P, Padovani L, Rombi B, Scarzello G, Schwarz R, Seiersen K, Seravalli E, Thorp N, Whitfield G, Boterberg T, Janssens G
LANCET ONCOL. 2019;20(3):e155-e166.
Light-controlled inhibition of BRAFV600E kinase
Hoorens M, Ourailidou M, Rodat T, van der Wouden P, Kobauri P, Kriegs M, Peifer C, Feringa B, Dekker F, Szymanski W
EUR J MED CHEM. 2019;179:133-146.
Long-term Follow-up and Patterns of Recurrence of Patients With Oligometastatic NSCLC Treated With Pulmonary SBRT
Hörner-Rieber J, Bernhardt D, Blanck O, Duma M, Eich H, Gerum S, Gkika E, Hass P, Henkenberens C, Herold H, Hildebrandt G, Imhoff D, Kahl H, Janssen S, Jurianz K, Krempien R, Lautenschläger S, Lohaus F, Mueller A, Petersen C, Sackerer I, Scafa D, Schrade E, Uhlmann L, Wittig A, Guckenberger M
CLIN LUNG CANCER. 2019;20(6):e667-e677.
The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness
Kari V, Raul S, Henck J, Kitz J, Kramer F, Kosinsky R, Übelmesser N, Mansour W, Eggert J, Spitzner M, Najafova Z, Bastians H, Grade M, Gaedcke J, Wegwitz F, Johnsen S
CLIN EPIGENETICS. 2019;11(1):4.
The impact of local control on overall survival after stereotactic body radiotherapy for liver and lung metastases from colorectal cancer: a combined analysis of 388 patients with 500 metastases
Klement R, Abbasi-Senger N, Adebahr S, Alheid H, Allgaeuer M, Becker G, Blanck O, Boda-Heggemann J, Brunner T, Duma M, Eble M, Ernst I, Gerum S, Habermehl D, Hass P, Henkenberens C, Hildebrandt G, Imhoff D, Kahl H, Klass N, Krempien R, Lewitzki V, Lohaus F, Ostheimer C, Papachristofilou A, Petersen C, Rieber J, Schneider T, Schrade E, Semrau R, Wachter S, Wittig A, Guckenberger M, Andratschke N
BMC CANCER. 2019;19(1):173.
Radiomics of Brain MRI: Utility in Prediction of Metastatic Tumor Type
Kniep H, Madesta F, Schneider T, Hanning U, Schönfeld M, Schön G, Fiehler J, Gauer T, Werner R, Gellissen S
RADIOLOGY. 2019;290(2):479-487.
A functional ex vivo assay to detect PARP1-EJ repair and radiosensitization by PARP-inhibitor in prostate cancer
Köcher S, Beyer B, Lange T, Nordquist L, Volquardsen J, Burdak-Rothkamm S, Schlomm T, Petersen C, Rothkamm K, Mansour W
INT J CANCER. 2019;144(7):1685-1696.
Analyzing expression and phosphorylation of the EGF receptor in HNSCC
Kriegs M, Clauditz T, Hoffer K, Bartels J, Buhs S, Gerull H, Zech H, Bußmann L, Struve N, Rieckmann T, Petersen C, Betz C, Rothkamm K, Nollau P, Münscher A
SCI REP-UK. 2019;9(1):13564.
Toxicity and risk factors after combined high-dose-rate brachytherapy and external beam radiation therapy in men ≥75 years with localized prostate cancer
Löser A, Beyer B, Carl C, Löser B, Nagaraj Y, Frenzel T, Petersen C, Krüll A, Graefen M, Schwarz R
STRAHLENTHER ONKOL. 2019;195(5):374-382.
Retrospective analysis of central venous catheters in elective intracranial surgery - Is there any benefit?
Löser B, Recio Ariza O, März A, Löser A, Grensemann J, Petzoldt M, Reuter D, Weber F, Glass Ä, Haas S
PLOS ONE. 2019;14(12):e0226641.
Anästhesie in der gastrointestinalen Endoskopie: perorale endoskopische Myotomie
Löser B, Werner Y, Löser A, Rösch T, Petzoldt M
ANAESTHESIST. 2019;68(9):607-614.
Assembling the brain trust: the multidisciplinary imperative in neuro-oncology
Ludmir E, Mahajan A, Ahern V, Ajithkumar T, Alapetite C, Bernier-Chastagner V, Bindra R, Bishop A, Bolle S, Brown P, Carrie C, Chalmers A, Chang E, Chung C, Dieckmann K, Esiashvili N, Gandola L, Ghia A, Gondi V, Grosshans D, Harrabi S, Horan G, Indelicato D, Jalali R, Janssens G, Krause M, Laack N, Laperriere N, Laprie A, Li J, Marcus K, McGovern S, Merchant T, Merrell K, Padovani L, Parkes J, Paulino A, Schwarz R, Shih H, Souhami L, Sulman E, Taylor R, Thorp N, Timmermann B, Wheeler G, Wolden S, Woodhouse K, Yeboa D, Yock T, Kortmann R, McAleer M
NAT REV CLIN ONCOL. 2019;16(8):521-522.
Self-consistent deep learning-based boosting of 4D cone-beam computed tomography reconstruction
Madesta F, Gauer T, Sentker T, Werner R
2019. Medical Imaging 2019: Image Processing. 1. Aufl. SPIE , 1094902.
Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity
Marcar L, Bardhan K, Gheorghiu L, Dinkelborg P, Pfäffle H, Liu Q, Wang M, Piotrowska Z, Sequist L, Borgmann K, Settleman J, Engelman J, Hata A, Willers H
CELL REP. 2019;27(12):3422-3432.e4.
Liquid application method for time-resolved analyses by serial synchrotron crystallography
Mehrabi P, Schulz E, Agthe M, Horrell S, Bourenkov G, von Stetten D, Leimkohl J, Schikora H, Schneider T, Pearson A, Tellkamp F, Miller R
NAT METHODS. 2019;16(10):979-982.
Cancer Stem Cells and Radioresistance: DNA Repair and Beyond
Meyer F, Borgmann K, Schulz A, Dubrovska A
CANCERS. 2019;2019(11):1-20.
Feasibility of clinical electron beam formation using polymer materials produced by fused deposition modeling
Miloichikova I, Bulavskaya A, Cherepennikov Y, Gavrikov B, Gargioni E, Belousov D, Stuchebrov S
PHYS MEDICA. 2019;64:188-194.
Effect of Postoperative Radiotherapy for Brain Metastases: An Analysis
Oertel M, Baehr A, Habibeh O, Haverkamp U, Stummer W, Eich H, Trog D
ONCOL RES TREAT. 2019;42(5):256-262.
Lokal-ablative Radiotherapie des oligometastasierten Prostatakarzinoms mit Überlebensvorteil
Oing C, Petersen C, Bokemeyer C
ONKOLOGE. 2019;25(9):827-828.
Strahlentherapeutische Studien bei Kopf-Hals-Tumoren - Highlights der ASCO-Jahrestagung 2019
Ott S, Wiegel T, Hoffmann T, Petersen C, Tribius S, Laban S
HNO. 2019;67(12):918-924.
Determining dose enhancement factors of high-Z nanoparticles from simulations where lateral secondary particle disequilibrium exists
Rabus H, Gargioni E, Li W, Nettelbeck H, Villagrasa C
PHYS MED BIOL. 2019;2019(64):.
Epidemiology and Treatment of Patients with Haemophilia in Austria-Update from the Austrian Haemophilia Registry
Rejtő J, Reitter-Pfoertner S, Kepa S, Feistritzer C, Grundbichler M, Hörbst A, Jones N, Muntean W, Neumeister P, Oberbichler S, Schuster G, Schwarz R, Thom K, Zwiauer K, Streif W, Male C, Pabinger I
HAMOSTASEOLOGIE. 2019;39(3):284-293.
Clonality of circulating tumor cells in breast cancer brain metastasis patients
Riebensahm C, Joosse S, Mohme M, Hanssen A, Matschke J, Goy Y, Witzel I, Lamszus K, Kropidlowski J, Petersen C, Kolb-Kokocinski A, Sauer S, Borgmann K, Glatzel M, Müller V, Westphal M, Riethdorf S, Pantel K, Wikman H
BREAST CANCER RES. 2019;21(1):101.
The inflammation-reducing compatible solute ectoine does not impair the cytotoxic effect of ionizing radiation on head and neck cancer cells
Rieckmann T, Gatzemeier F, Christiansen S, Rothkamm K, Münscher A
SCI REP-UK. 2019;9(1):6594.
The failure of cetuximab-based de-intensified regimes for HPV-positive OPSCC: A radiobiologists perspective
Rieckmann T, Kriegs M
CLIN TRANSL RAD ONCO. 2019;17:47-50.
Modulation of radiation sensitivity and antitumor immunity by viral pathogenic factors: Implications for radio-immunotherapy.
Rödel F, Martin D, Balermpas P, Wieland U, Winkelmann R, Rieckmann T, Falk S, Rödel C, Fokas E
BBA-REV CANCER. 2019;1871(1):126-137.
EGFR and HER3 expression in circulating tumor cells and tumor tissue from non-small cell lung cancer patients
Scharpenseel H, Hanssen A, Loges S, Mohme M, Bernreuther C, Peine S, Lamszus K, Goy Y, Petersen C, Westphal M, Glatzel M, Riethdorf S, Pantel K, Wikman H
SCI REP-UK. 2019;9(1):7406.
In HPV-Positive HNSCC Cells, Functional Restoration of the p53/p21 Pathway by Proteasome Inhibitor Bortezomib Does Not Affect Radio- or Chemosensitivity
Seltzsam S, Ziemann F, Dreffke K, Preising S, Arenz A, Schötz U, Engenhart-Cabillic R, Dikomey E, Wittig A
TRANSL ONCOL. 2019;12(3):417-425.
Patient-specific 4D Monte Carlo dose accumulation using correspondence-model-based motion prediction
Sentker T, Madesta F, Werner R
2019. Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling. Fei B, Linte C (Hrsg.). 1. Aufl. SPIE , 1095109.
Cancer Cells Expressing Oncogenic Rat Sarcoma Show Drug-Addiction Toward Epidermal Growth Factor Receptor Antibodies Mediated by Sustained MAPK Signaling
Tintelnot J, Metz S, Trentmann M, Oberle A, von Wenserski L, Schultheiß C, Braig F, Kriegs M, Fehse B, Riecken K, Bokemeyer C, Stein A, Binder M
FRONT ONCOL. 2019;9:1559.
ASSESSING THE CONTRIBUTION OF CROSS-SECTIONS TO THE UNCERTAINTY OF MONTE CARLO CALCULATIONS IN MICRO- AND NANODOSIMETRY
Villagrasa C, Bordage M, Bueno M, Bug M, Chiriotti S, Gargioni E, Heide B, Nettelbeck H, Parisi A, Rabus H
RADIAT PROT DOSIM. 2019;183(1-2):11-16.
Intelligent 4D CT sequence scanning (i4DCT): Concept and performance evaluation
Werner R, Sentker T, Madesta F, Gauer T, Hofmann C
MED PHYS. 2019;46(8):3462-3474.
The SBRT database initiative of the German Society for Radiation Oncology (DEGRO): patterns of care and outcome analysis of stereotactic body radiotherapy (SBRT) for liver oligometastases in 474 patients with 623 metastases
Andratschke N, Alheid H, Allgäuer M, Becker G, Blanck O, Boda-Heggemann J, Brunner T, Duma M, Gerum S, Guckenberger M, Hildebrandt G, Klement R, Lewitzki V, Ostheimer C, Papachristofilou A, Petersen C, Schneider T, Semrau R, Wachter S, Habermehl D
BMC CANCER. 2018;18(1):283.
Clinico-radiological comparison and short-term prognosis of single acute pancreatitis and recurrent acute pancreatitis including pancreatic volumetry
Avanesov M, Löser A, Smagarynska A, Keller S, Guerreiro H, Tahir E, Karul M, Adam G, Yamamura J
PLOS ONE. 2018;13(10):e0206062.
Early heme oxygenase 1 induction delays tumour initiation and enhances DNA damage repair in liver macrophages of Mdr2 mice
Barikbin R, Berkhout L, Bolik J, Schmidt-Arras D, Ernst T, Ittrich H, Adam G, Parplys A, Casar C, Krech T, Karimi K, Sass G, Tiegs G
SCI REP-UK. 2018;8(1):16238.
Establishment of the First Well-differentiated Human Pancreatic Neuroendocrine Tumor Model
Benten D, Behrang Y, Unrau L, Weissmann V, Wolters-Eisfeld G, Burdak-Rothkamm S, Stahl F, Anlauf M, Grabowski P, Möbs M, Dieckhoff J, Sipos B, Fahl M, Eggers C, Perez D, Bockhorn M, Izbicki J, Lohse A, Schrader J
MOL CANCER RES. 2018;16(3):496-507.
B-1252: The impact of [68Ga]PSMA I&T PET/CT on radiotherapy planning in patients with biochemical cancer relapse after radical prostatectomy in prostate cancer.
Berliner C, Frenzel T, Tienken M, Abel M, Klutmann S, Beyersdorff D, Adam G, Krüll A, Bannas P
INSIGHTS IMAGING. 2018;9(Suppl 1):.
Radiation-induced bystander and systemic effects serve as a unifying model system for genotoxic stress responses
Burdak-Rothkamm S, Rothkamm K
MUTAT RES-REV MUTAT. 2018;778:13-22.
Verbessertes Überleben beim fortgeschrittenen oder metastasierten Prostatakarzinom durch zusätzliches Abirateron zur initialen Androgendeprivation
Carl C, Schwarz R, Petersen C
STRAHLENTHER ONKOL. 2018;194(3):266-268.
Prevalence of fibroblast growth factor receptor 1 (FGFR1) amplification in squamous cell carcinomas of the head and neck
Clauditz T, Böttcher A, Hanken H, Borgmann K, Sauter G, Wilczak W, Grob T, Münscher A
J CANCER RES CLIN. 2018;144(1):53-61.
Quality of training in radiation oncology in Germany: where do we stand? Results from a 2016/2017 survey performed by the working group "young DEGRO" of the German society of radiation oncology (DEGRO)
Dietzel C, Jablonska K, Niyazi M, Gauer T, Ebert N, Ostheimer C, Krug D
STRAHLENTHER ONKOL. 2018;194(4):293-302.
Current studies of immunotherapy in head and neck cancer
Dogan V, Rieckmann T, Münscher A, Busch C
CLIN OTOLARYNGOL. 2018;43(1):13-21.
AN ALGORITHM TO DETERMINE THE NANODOSIMETRIC IMPACT OF GOLD NANOPARTICLES ON CELL MODELS
Dressel T, Bug M, Gargioni E, Rabus H
RADIAT PROT DOSIM. 2018;2019(183):.
Stereotactic Radiosurgery Alone for One to Two Brain Metastases from Cancer of Unknown Primary
Dziggel L, Bajrovic A, Schild S, Rades D
ANTICANCER RES. 2018;38(1):565-567.
Under-reported dosimetry errors due to interplay effects during VMAT dose delivery in extreme hypofractionated stereotactic radiotherapy
Gauer T, Sothmann T, Blanck O, Petersen C, Werner R
STRAHLENTHER ONKOL. 2018;194(6):570-579.
Predictive and prognostic value of tumor volume and its changes during radical radiotherapy of stage III non-small cell lung cancer: A systematic review
Käsmann L, Niyazi M, Blanck O, Baues C, Baumann R, Dobiasch S, Eze C, Fleischmann D, Gauer T, Giordano F, Goy Y, Hausmann J, Henkenberens C, Kaul D, Klook L, Krug D, Mäurer M, Panje C, Rosenbrock J, Sautter L, Schmitt D, Süß C, Thieme A, Trommer-Nestler M, Ziegler S, Ebert N, Medenwald D, Ostheimer C
STRAHLENTHER ONKOL. 2018;194(2):79-90.
Stereotactic body radiotherapy (SBRT) for multiple pulmonary oligometastases: Analysis of number and timing of repeat SBRT as impact factors on treatment safety and efficacy
Klement R, Hoerner-Rieber J, Adebahr S, Andratschke N, Blanck O, Boda-Heggemann J, Duma M, Eble M, Eich H, Flentje M, Gerum S, Hass P, Henkenberens C, Hildebrandt G, Imhoff D, Kahl K, Klass N, Krempien R, Lohaus F, Petersen C, Schrade E, Wendt T, Wittig A, Guckenberger M
RADIOTHER ONCOL. 2018;127(2):246-252.
Toxicity and risk factors after combined high-dose-rate brachytherapy and external beam radiation therapy in men ≥75 years with localized prostate cancer
Löser A, Beyer B, Carl C, Löser B, Nagaraj Y, Frenzel T, Petersen C, Krüll A, Graefen M, Schwarz R
STRAHLENTHER ONKOL. 2018 [Epub ahead of print].
Intravenous Regional Anesthesia: A historical overview and clinical review
Löser B, Petzoldt M, Löser A, Bacon D, Goerig M
J Anesth Hist. 2018 [Epub ahead of print].
Loss of PTEN-assisted G2/M checkpoint impedes homologous recombination repair and enhances radio-curability and PARP inhibitor treatment response in prostate cancer
Mansour W, Tennstedt P, Volquardsen J, Oing C, Kluth M, Hube-Magg C, Borgmann K, Simon R, Petersen C, Dikomey E, Rothkamm K
SCI REP-UK. 2018;8(1):3947.
Influence of deformable image registration on 4D dose simulation for extracranial SBRT: A multi-registration framework study
Mogadas N, Sothmann T, Knopp T, Gauer T, Petersen C, Werner R
RADIOTHER ONCOL. 2018;127(2):225-232.
Worth a local treatment? - Analysis of modern radiotherapy concepts for oligometastatic prostate cancer
Oertel M, Scobioala S, Kroeger K, Baehr A, Stegger L, Haverkamp U, Schäfers M, Eich H
RADIAT ONCOL. 2018;13(1):185.
BCL2-overexpressing prostate cancer cells rely on PARP1-dependent end-joining and are sensitive to combined PARP inhibitor and radiation therapy
Oing C, Tennstedt P, Simon R, Volquardsen J, Borgmann K, Bokemeyer C, Petersen C, Dikomey E, Rothkamm K, Mansour W
CANCER LETT. 2018;423:60-70.
5-Azacitidine Exerts Prolonged Pro-Apoptotic Effects and Overcomes Cisplatin-Resistance in Non-Seminomatous Germ Cell Tumor Cells
Oing C, Verem I, Mansour W, Bokemeyer C, Dyshlovoy S, Honecker F
INT J MOL SCI. 2018;20(1):21.
Strahlentherapeutische Studien bei Kopf-Hals-Tumoren – Highlights der ASCO-Jahrestagung 2018
Ott S, Wiegel T, Laban S, Hoffmann T, Petersen C, Tribius S
HNO. 2018;66(12):901-906.
Evaluation and reduction of magnetic resonance imaging artefacts induced by distinct plates for osseous fixation: an in vitro study @ 3 T
Rendenbach C, Schoellchen M, Bueschel J, Gauer T, Sedlacik J, Kutzner D, Vallittu P, Heiland M, Smeets R, Fiehler J, Siemonsen S
DENTOMAXILLOFAC RAD. 2018;47(7):20170361.
Analysis of the influence of imaging-related uncertainties on cerebral aneurysm deformation quantification using a no-deformation physical flow phantom
Schetelig D, Sedlacik J, Fiehler J, Frölich A, Knopp T, Sothmann T, Waschkewitz J, Werner R
SCI REP-UK. 2018;8(1):11004.
Axitinib: A Photoswitchable Approved Tyrosine Kinase Inhibitor
Schmidt D, Rodat T, Heintze L, Weber J, Horbert R, Girreser U, Raeker T, Bußmann L, Kriegs M, Hartke B, Peifer C
CHEMMEDCHEM. 2018;13(22):2415-2426.
GDL-FIRE4D: Deep Learning-based fast 4D CT image registration
Sentker T, Madesta F, Werner R
2018. Medical Image Computing and Computer Assisted Intervention – MICCAI 2018. Frangi A, Schnabel J, Davatzikos C, Alberola-López C, Fichtinger G (Hrsg.). 1. Aufl. Springer, 765 - 773.
Influence of 4D CT motion artifacts on correspondence model-based 4D dose accumulation
Sothmann T, Gauer T, Werner R
2018. Medical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling. Fei B, Webster R (Hrsg.). 1. Aufl. SPIE , 105760F-1 - 105760F-7.
Socioeconomic status and quality of life in patients with locally advanced head and neck cancer
Tribius S, Meyer M, Pflug C, Hanken H, Busch C, Krüll A, Petersen C, Bergelt C
STRAHLENTHER ONKOL. 2018;194(8):737-749.
Fanconi anemia and homologous recombination gene variants are associated with functional DNA repair defects and poor outcome in patients with advanced head and neck squamous cell carcinoma
Verhagen C, Vossen D, Borgmann K, Hageman F, Grénman R, Verwijs-Janssen M, Mout L, Kluin R, Nieuwland M, Severson T, Velds A, Kerkhoven R, O'Connor M, van der Heijden M, van Velthuysen M, Verheij M, Wreesmann V, Wessels L, van den Brekel M, Vens C
ONCOTARGET. 2018;9(26):18198-18213.
Technical considerations for automated low-pitch spiral 4D CT scanning protocol selection
Werner R, Sothmann T, Madesta F, Gauer T, Hofmann C
2018. Medical Imaging 2018: Physics of Medical Imaging. Lo J, Schmidt T, Chen G (Hrsg.). 1. Aufl. SPIE , 105733Y-1-105733Y-6.
Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032/045OL, December 2017) - Part 2 with Recommendations for the Therapy of Primary, Recurrent and Advanced Breast Cancer
Wöckel A, Festl J, Stüber T, Brust K, Krockenberger M, Heuschmann P, Jírů-Hillmann S, Albert U, Budach W, Follmann M, Janni W, Kopp I, Kreienberg R, Kühn T, Langer T, Nothacker M, Scharl A, Schreer I, Link H, Engel J, Fehm T, Weis J, Welt A, Steckelberg A, Feyer P, König K, Hahne A, Baumgartner T, Kreipe H, Knoefel W, Denkinger M, Brucker S, Lüftner D, Kubisch C, Gerlach C, Lebeau A, Siedentopf F, Petersen C, Bartsch H, Schulz-Wendtland R, Hahn M, Hanf V, Müller-Schimpfle M, Henscher U, Roncarati R, Katalinic A, Heitmann C, Honegger C, Paradies K, Bjelic-Radisic V, Degenhardt F, Wenz F, Rick O, Hölzel D, Zaiss M, Kemper G, Budach V, Denkert C, Gerber B, Tesch H, Hirsmüller S, Sinn H, Dunst J, Münstedt K, Bick U, Fallenberg E, Tholen R, Hung R, Baumann F, Beckmann M, Blohmer J, Fasching P, Lux M, Harbeck N, Hadji P, Hauner H, Heywang-Köbrunner S, Huober J, Hübner J, Jackisch C, Loibl S, Lück H, von Minckwitz G, Möbus V, Müller V, Nöthlings U, Schmidt M, Schmutzler R, Schneeweiss A, Schütz F, Stickeler E, Thomssen C, Untch M, Wesselmann S, Bücker A, Buck A, Stangl S
GEBURTSH FRAUENHEILK. 2018;78(11):1056-1088.
Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032/045OL, December 2017) - Part 1 with Recommendations for the Screening, Diagnosis and Therapy of Breast Cancer
Wöckel A, Festl J, Stüber T, Brust K, Stangl S, Heuschmann P, Albert U, Budach W, Follmann M, Janni W, Kopp I, Kreienberg R, Kühn T, Langer T, Nothacker M, Scharl A, Schreer I, Link H, Engel J, Fehm T, Weis J, Welt A, Steckelberg A, Feyer P, König K, Hahne A, Kreipe H, Knoefel W, Denkinger M, Brucker S, Lüftner D, Kubisch C, Gerlach C, Lebeau A, Siedentopf F, Petersen C, Bartsch H, Schulz-Wendtland R, Hahn M, Hanf V, Müller-Schimpfle M, Henscher U, Roncarati R, Katalinic A, Heitmann C, Honegger C, Paradies K, Bjelic-Radisic V, Degenhardt F, Wenz F, Rick O, Hölzel D, Zaiss M, Kemper G, Budach V, Denkert C, Gerber B, Tesch H, Hirsmüller S, Sinn H, Dunst J, Münstedt K, Bick U, Fallenberg E, Tholen R, Hung R, Baumann F, Beckmann M, Blohmer J, Fasching P, Lux M, Harbeck N, Hadji P, Hauner H, Heywang-Köbrunner S, Huober J, Hübner J, Jackisch C, Loibl S, Lück H, von Minckwitz G, Möbus V, Müller V, Nöthlings U, Schmidt M, Schmutzler R, Schneeweiss A, Schütz F, Stickeler E, Thomssen C, Untch M, Wesselmann S, Bücker A, Krockenberger M
GEBURTSH FRAUENHEILK. 2018;78(10):927-948.
Functional Outcomes and Quality of Life After Radical Prostatectomy Only Versus a Combination of Prostatectomy with Radiation and Hormonal Therapy
Adam M, Tennstedt P, Lanwehr D, Tilki D, Steuber T, Beyer B, Thederan I, Heinzer H, Haese A, Salomon G, Budäus L, Michl U, Pehrke D, Stattin P, Bernard J, Klaus B, Pompe R, Petersen C, Huland H, Graefen M, Schwarz R, Huber W, Loeb S, Schlomm T
EUR UROL. 2017;71(3):330-336.
Uncertainty of fast biological radiation dose assessment for emergency response scenarios
Ainsbury E, Higueras M, Puig P, Einbeck J, Samaga D, Barquinero J, Barrios L, Brzozowska B, Fattibene P, Gregoire E, Jaworska A, Lloyd D, Oestreicher U, Romm H, Rothkamm K, Roy L, Sommer S, Terzoudi G, Thierens H, Trompier F, Vral A, Woda C
INT J RADIAT BIOL. 2017;93(1):127-135.
Diagnosing acute pancreatitis-Clinical and radiological characterisation of patients without threefold increase of serum lipase
Avanesov M, Löser A, Keller S, Weinrich J, Laqmani A, Adam G, Karul M, Yamamura J
EUR J RADIOL. 2017;95:278-285.
Detection rate of PET/CT in patients with biochemical relapse of prostate cancer using [(68)Ga]PSMA I&T and comparison with published data of [(68)Ga]PSMA HBED-CC
Berliner C, Tienken M, Frenzel T, Kobayashi Y, Helberg A, Kirchner U, Klutmann S, Beyersdorff D, Budäus L, Wester H, Mester J, Bannas P
EUR J NUCL MED MOL I. 2017;44(4):670-677.
Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-KPolymorphism
Braig F, Kriegs M, Voigtlaender M, Habel B, Grob T, Biskup K, Blanchard V, Sack M, Thalhammer A, Ben Batalla I, Braren I, Laban S, Danielczyk A, Goletz S, Jakubowicz E, Märkl B, Trepel M, Knecht R, Riecken K, Fehse B, Loges S, Bokemeyer C, Binder M
CANCER RES. 2017;77(5):1188-1199.
G2-checkpoint targeting and radiosensitization of HPV/p16-positive HNSCC cells through the inhibition of Chk1 and Wee1
Busch C, Kröger M, Jensen J, Kriegs M, Gatzemeier F, Petersen C, Münscher A, Rothkamm K, Rieckmann T
RADIOTHER ONCOL. 2017;122(2):260-266.
Clinical Factors Asssociated with Treatment Outcomes following Whole-brain Irradiation in Patients with Prostate Cancer
Dziggel L, Schild S, Veninga T, Bajrovic A, Rades D
IN VIVO. 2017;31(1):35-38.
EURO-BOSS: A European study on chemotherapy in bone-sarcoma patients aged over 40: Outcome in primary high-grade osteosarcoma
Ferrari S, Bielack S, Smeland S, Longhi A, Egerer G, Sundby Hall K, Donati D, Kevric M, Brosjö O, Comandone A, Werner M, Monge O, Palmerini E, Berdel W, Bjerkehagen B, Paioli A, Lorenzen S, Eriksson M, Gambarotti M, Tunn P, Jebsen N, Cesari M, von Kalle T, Ferraresi V, Schwarz R, Bertulli R, Kasparek A, Grignani G, Krasniqi F, Sorg B, Hecker-Nolting S, Picci P, Reichardt P
TUMORI J. 2017;104(1):30-36.
Magnetic resonance imaging for precise radiotherapy of small laboratory animals
Frenzel T, Kaul M, Ernst T, Salamon J, Jäckel M, Schumacher U, Krüll A
Z MED PHYS. 2017;27:6-12.
Analyzing the influence of kinase inhibitors on DNA repair by differential proteomics of chromatin-interacting proteins and nuclear phospho-proteins
Gleißner L, Kwiatkowski M, Myllynen L, Steffen P, Petersen C, Rothkamm K, Schlüter H, Kriegs M
ONCOTARGET. 2017;8(67):110983-110993.
Stereotactic body radiotherapy for oligo-metastatic liver disease - Influence of pre-treatment chemotherapy and histology on local tumor control
Klement R, Guckenberger M, Alheid H, Allgäuer M, Becker G, Blanck O, Boda-Heggemann J, Brunner T, Duma M, Gerum S, Habermehl D, Hildebrandt G, Lewitzki V, Ostheimer C, Papachristofilou A, Petersen C, Schneider T, Semrau R, Wachter S, Andratschke N
RADIOTHER ONCOL. 2017;123(2):227-233.
Capabilities of the RENEB network for research and large scale radiological and nuclear emergency situations
Monteiro Gil O, Vaz P, Romm H, De Angelis C, Antunes A, Barquinero J, Beinke C, Bortolin E, Burbidge C, Cucu A, Della Monaca S, Domene M, Fattibene P, Gregoire E, Hadjidekova V, Kulka U, Lindholm C, Meschini R, M'Kacher R, Moquet J, Oestreicher U, Palitti F, Pantelias G, Montoro Pastor A, Popescu I, Quattrini M, Ricoul M, Rothkamm K, Sabatier L, Sebastià N, Sommer S, Terzoudi G, Testa A, Trompier F, Vral A
INT J RADIAT BIOL. 2017;93(1):136-141.
The second gamma-H2AX assay inter-comparison exercise carried out in the framework of the European biodosimetry network (RENEB)
Moquet J, Barnard S, Staynova A, Lindholm C, Monteiro Gil O, Martins V, Rößler U, Vral A, Vandevoorde C, Wojewódzka M, Rothkamm K
INT J RADIAT BIOL. 2017;93(1):58-64.
Time for standardization of SBRT planning through large scale clinical data and guideline-based approaches
Moustakis C, Blanck O, Ebrahimi F, Ka Heng Chan M, Ernst I, Krieger T, Duma M, Oechsner M, Ganswindt U, Heinz C, Alheit H, Blank H, Nestle U, Wiehle R, Kornhuber C, Ostheimer C, Petersen C, Pollul G, Baus W, Altenstein G, Beckers E, Jurianz K, Sterzing F, Kretschmer M, Seegenschmiedt H, Maass T, Droege S, Wolf U, Schoeffler J, Haverkamp U, Eich H, Guckenberger M
STRAHLENTHER ONKOL. 2017;193(12):1068-1069.
Planning benchmark study for SBRT of early stage NSCLC: Results of the DEGRO Working Group Stereotactic Radiotherapy
Moustakis C, Blanck O, Ebrahimi Tazehmahalleh F, Ka Heng Chan M, Ernst I, Krieger T, Duma M, Oechsner M, Ganswindt U, Heinz C, Alheit H, Blank H, Nestle U, Wiehle R, Kornhuber C, Ostheimer C, Petersen C, Pollul G, Baus W, Altenstein G, Beckers E, Jurianz K, Sterzing F, Kretschmer M, Seegenschmiedt H, Maass T, Droege S, Wolf U, Schoeffler J, Haverkamp U, Eich H, Guckenberger M
STRAHLENTHER ONKOL. 2017;193(10):780-790.
DNA Fiber Spreading Assay to Test HDACi Effects on DNA and Its Replication
Nikolova T, Göder A, Parplys A, Borgmann K
Methods Mol Biol. 2017;1510:103-113.
Monoubiquitination of histone H2B – a potential new target in treatment resistant germ cell tumors.
Oing C, Dyshlovoy S, Burandt E, Amsberg G, Honecker F, Bokemeyer C, Rothkamm K, Mansour W
ONCOL RES TREAT. 2017;40:95-96.
European Society of Gynaecological Oncology Guidelines for the Management of Patients With Vulvar Cancer
Oonk M, Planchamp F, Baldwin P, Bidzinski M, Brännström M, Landoni F, Mahner S, Mahantshetty U, Mirza M, Petersen C, Querleu D, Regauer S, Rob L, Rouzier R, Ulrikh E, van der Velden J, Vergote I, Woelber L, van der Zee A
INT J GYNECOL CANCER. 2017;27(4):832-837.
Möglichkeiten der lokal-ablativen Bestrahlung (SBRT) bei metastasiertem kolorektalem Karzinom
Petersen C, Gauer T
RADIOLOGE. 2017;57(2):105-110.
Möglichkeiten der lokal-ablativen Bestrahlung (SBRT) bei metastasiertem kolorektalem Karzinom
Petersen C, Gauer T
RADIOLOGE. 2017;57(2):105-110.
Predictive Factors and a Survival Score for Patients Irradiated for Metastatic Spinal Cord Compression from Carcinoma of the Salivary Glands
Rades D, Bajrovic A, Bartscht T
ANTICANCER RES. 2017;37(12):7011-7015.
A matched-pair analysis comparing whole-brain radiotherapy with and without a stereotactic boost for intracerebral control and overall survival in patients with one to three cerebral metastases
Rades D, Janssen S, Bajrovic A, Khoa M, Veninga T, Schild S
RADIAT ONCOL. 2017;12(1):69.
A New Scoring Tool to Assess Overall Survival in Patients With Intracerebral Metastases From Gynecological Cancers
Rades D, Janssen S, Bajrovic A, Veninga T, Fischer D, Schild S
INT J GYNECOL CANCER. 2017;27(3):597-602.
A matched-pair study comparing whole-brain irradiation alone to radiosurgery or fractionated stereotactic radiotherapy alone in patients irradiated for up to three brain metastases
Rades D, Janssen S, Dziggel L, Blanck O, Bajrovic A, Veninga T, Schild S
BMC CANCER. 2017;17(1):30.
Comparing two lower-dose cisplatin programs for radio-chemotherapy of locally advanced head-and-neck cancers
Rades D, Seidl D, Janssen S, Strojan P, Karner K, Bajrovic A, Hakim S, Wollenberg B, Schild S
EUR ARCH OTO-RHINO-L. 2017;274(2):1021-1027.
Influence of Institutional Experience and Technological Advances on Outcome of Stereotactic Body Radiation Therapy for Oligometastatic Lung Disease
Rieber J, Abbassi-Senger N, Adebahr S, Andratschke N, Blanck O, Duma M, Eble M, Ernst I, Flentje M, Gerum S, Hass P, Henkenberens C, Hildebrandt G, Imhoff D, Kahl H, Klass N, Krempien R, Lohaus F, Lohr F, Petersen C, Schrade E, Streblow J, Uhlmann L, Wittig A, Sterzing F, Guckenberger M
INT J RADIAT ONCOL. 2017;98(3):511-520.
Intercenter validation of a knowledge based model for automated planning of volumetric modulated arc therapy for prostate cancer. The experience of the German RapidPlan Consortium
Schubert C, Waletzko O, Weiss C, Voelzke D, Toperim S, Roeser A, Puccini S, Piroth M, Mehrens C, Kueter J, Hierholz K, Gerull K, Fogliata A, Block A, Cozzi L
PLOS ONE. 2017;12(5):e0178034.
Artefacts in multimodal imaging of titanium, zirconium and binary titanium-zirconium alloy dental implants: an in vitro study
Smeets R, Schöllchen M, Gauer T, Aarabi G, Assaf A, Rendenbach C, Beck-Broichsitter B, Semmusch J, Sedlacik J, Heiland M, Fiehler J, Siemonsen S
DENTOMAXILLOFAC RAD. 2017;46(2):20160267.
4D dose simulation in volumetric arc therapy: Accuracy and affecting parameters
Sothmann T, Gauer T, Werner R
PLOS ONE. 2017;12(2):e0172810.
Correspondence model-based 4D VMAT dose simulation for analysis of local metastasis recurrence after extracranial SBRT
Sothmann T, Gauer T, Wilms M, Werner R
PHYS MED BIOL. 2017;62(23):9001-9017.
Adjuvant radiation therapy is associated with better oncological outcome compared with salvage radiation therapy in patients with pN1 prostate cancer treated with radical prostatectomy
Tilki D, Preisser F, Tennstedt P, Tober P, Mandel P, Schlomm T, Steuber T, Huland H, Schwarz R, Petersen C, Graefen M, Ahyai S
BJU INT. 2017;119(5):717-723.
Reduction of breathing irregularity-related motion artifacts in low-pitch spiral 4D CT by optimized projection binning
Werner R, Hofmann C, Mücke E, Gauer T
RADIAT ONCOL. 2017;12(1):article ID 100.
The RENEB operational basis: complement of established biodosimetric assays
Wojcik A, Oestreicher U, Barrios L, Vral A, Terzoudi G, Ainsbury E, Rothkamm K, Trompier F, Kulka U
INT J RADIAT BIOL. 2017;93(1):15-19.
Roscovitine strongly enhances the effect of olaparib on radiosensitivity for HPV neg. but not for HPV pos. HNSCC cell lines
Ziemann F, Seltzsam S, Dreffke K, Preising S, Arenz A, Subtil F, Rieckmann T, Engenhart-Cabillic R, Dikomey E, Wittig A
ONCOTARGET. 2017;8(62):105170-105183.
Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1
Bakr A, Köcher S, Volquardsen J, Petersen C, Borgmann K, Dikomey E, Rothkamm K, Mansour Khalfallah W
ONCOTARGET. 2016;7(36):57679-57693.
Functional crosstalk between DNA damage response proteins 53BP1 and BRCA1 regulates double strand break repair choice
Bakr A, Köcher S, Volquardsen J, Reimer R, Borgmann K, Dikomey E, Rothkamm K, Mansour Khalfallah W
RADIOTHER ONCOL. 2016;119(2):276-81.
Targeting Homologous Recombination by Pharmacological Inhibitors Enhances the Killing Response of Glioblastoma Cells Treated with Alkylating Drugs
Berte N, Piée-Staffa A, Piecha N, Wang M, Borgmann K, Kaina B, Nikolova T
MOL CANCER THER. 2016;15(11):2665-2678.
Five-year biochemical recurrence-free and overall survival following high-dose-rate brachytherapy with additional external beam or radical prostatectomy in patients with clinically localized prostate cancer
Boehm K, Schiffmann J, Tian Z, Lesmana H, Larcher A, Mandel P, Karakiewicz P, Graefen M, Schwarz R, Krüll A, Tilki D
UROL ONCOL-SEMIN ORI. 2016;34(3):e11-8.
DNA Repair
Borgmann K, Köcher S, Kriegs M, Mansour Khalfallah W, Parplys A, Rieckmann T, Rothkamm K
2016. Molecular Radio-Oncology. Baumann M, Krause M, Cordes N (Hrsg.). 1. Aufl. Berlin Heidelberg: Springer, 1-24.
Clustered localization of EGFRvIII in glioblastoma cells as detected by high precision localization microscopy
Boyd P, Struve N, Bach M, Eberle J, Gote M, Schock F, Cremer C, Kriegs M, Hausmann M
NANOSCALE. 2016;8(48):20037-20047.
Liquid biopsy monitoring uncovers acquired RAS-mediated resistance to cetuximab in a substantial proportion of patients with head and neck squamous cell carcinoma
Braig F, Voigtländer M, Schieferdecker A, Busch C, Laban S, Grob T, Kriegs M, Knecht R, Bokemeyer C, Binder M
ONCOTARGET. 2016;7(28):42988-42995.
Cyclin D1 gene amplification is highly homogeneous in breast cancer
Burandt E, Grünert M, Lebeau A, Choschzick M, Quaas A, Jänicke F, Müller V, Scholz U, Bokemeyer C, Petersen C, Geist S, Paluchowski P, Wilke C, Heilenkötter U, Simon R, Sauter G, Wilczak W
BREAST CANCER-TOKYO. 2016;23(1):111-9.
Similar cisplatin sensitivity of HPV-positive and -negative HNSCC cell lines
Busch C, Becker B, Kriegs M, Gatzemeier F, Krüger K, Möckelmann N, Fritz G, Petersen C, Knecht R, Rothkamm K, Rieckmann T
ONCOTARGET. 2016;7(24):35832-35842.
A dosimetric comparison of real-time adaptive and non-adaptive radiotherapy: A multi-institutional study encompassing robotic, gimbaled, multileaf collimator and couch tracking
Colvill E, Booth J, Nill S, Fast M, Bedford J, Oelfke U, Nakamura M, Poulsen P, Worm E, Hansen R, Ravkilde T, Scherman Rydhög J, Pommer T, Munck Af Rosenschold P, Lang S, Guckenberger M, Groh C, Herrmann C, Verellen D, Poels K, Wang L, Hadsell M, Sothmann T, Blanck O, Keall P
RADIOTHER ONCOL. 2016;119(1):159-65.
Targeting of β1 integrins impairs DNA repair for radiosensitization of head and neck cancer cells
Dickreuter E, Eke I, Krause M, Borgmann K, van Vugt M, Cordes N
ONCOGENE. 2016;35(11):1353-62.
Radiation DNA damage and use in cancer/therapeutics-translation of radiation modifiers
Dikomey E, Borgmann K, Köcher S, Kriegs M, Mansour Khalfallah W, Parplys A, Rieckmann T, Rothkamm K
2016. DNA Repair in Cancer Therapy. Kelley M, Fishel M (Hrsg.). 2. Aufl. London: Elsevier Science, 329 - 352.
DNA repair after oncological therapy (radiotherapy and chemotherapy)
Dikomey E, Borgmann K, Kriegs M, Mansour Khalfallah W, Petersen C, Rieckmann T
2016. Oxford Textbook of Oncology. Kerr D, Haller D, van de Velde C, Baumann M (Hrsg.). 3. Aufl. Oxford: Oxford University Press, 82-85.
Local Therapies Can Improve Intracerebral Control in Patients with Cerebral Metastasis from Gynecological Cancers
Dziggel L, Janssen S, Bajrovic A, Veninga T, Trang N, Khoa M, Schild S, Rades D
ANTICANCER RES. 2016;36(9):4777-80.
Cancer cell motility is affected through 3D cell culturing and SCF/c-Kit pathway but not by X-irradiation
Eberle F, Saulich M, Leinberger F, Seeger W, Engenhart-Cabillic R, Dikomey E, Hänze J, Hattar K, Subtil F
RADIOTHER ONCOL. 2016;119(3):537-43.
S100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci
Foertsch F, Szambowska A, Weise A, Zielinski A, Schlott B, Kraft F, Mrasek K, Borgmann K, Pospiech H, Grosse F, Melle C
CELL CYCLE. 2016;15(20):2766-79.
Targeted nanoparticles for tumour radiotherapy enhancement - the long dawn of a golden era?
Gargioni E, Schulz F, Raabe A, Burdak-Rothkamm S, Rieckmann T, Rothkamm K
ANN TRANSL MED. 2016;4(24):523.
Outcome and fewer indications for adjuvant therapy for patients with oral squamous cell carcinomas under standardized tumor board conditions
Gröbe A, Rybak L, Schön G, Smeets R, Tribius S, Schafhausen P, Clauditz T, Hanken H, Heiland M
J CANCER RES CLIN. 2016;142(2):505-20.
Local tumor control probability modeling of primary and secondary lung tumors in stereotactic body radiotherapy
Guckenberger M, Klement R, Allgäuer M, Andratschke N, Blanck O, Boda-Heggemann J, Dieckmann K, Duma M, Ernst I, Ganswindt U, Hass P, Henkenberens C, Holy R, Imhoff D, Kahl H, Krempien R, Lohaus F, Nestle U, Nevinny-Stickel M, Petersen C, Semrau S, Streblow J, Wendt T, Wittig A, Flentje M, Sterzing F
RADIOTHER ONCOL. 2016;118(3):485-91.
Constitutive gp130 activation rapidly accelerates the transformation of human hepatocytes via an impaired oxidative stress response
Heim D, Gil-Ibanez I, Herden J, Parplys A, Borgmann K, Schmidt-Arras D, Lohse A, Rose-John S, Wege H
ONCOTARGET. 2016;7(34):55639-55648.
A new Bayesian model applied to cytogenetic partial body irradiation estimation
Higueras M, Puig P, Ainsbury E, Vinnikov V, Rothkamm K
RADIAT PROT DOSIM. 2016;168(3):330-6.
A Scoring Instrument to Predict the Survival Prognoses of Patients with Metastatic Epidural Spinal Cord Compression from Gynecological Malignancies
Janssen S, Bajrovic A, Schild S, Rades D
ANTICANCER RES. 2016;36(10):5469-5472.
Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness
Kari V, Mansour Khalfallah W, Raul S, Baumgart S, Mund A, Grade M, Sirma H, Simon R, Will H, Dobbelstein M, Dikomey E, Johnsen S
EMBO REP. 2016;17(11):1609-1623.
Bayesian Cure Rate Modeling of Local Tumor Control: Evaluation in Stereotactic Body Radiation Therapy for Pulmonary Metastases
Klement R, Allgäuer M, Andratschke N, Blanck O, Boda-Heggemann J, Dieckmann K, Duma M, Ernst I, Flentje M, Ganswindt U, Hass P, Henkenberens C, Imhoff D, Kahl H, Krempien R, Lohaus F, Nestle U, Nevinny-Stickel M, Petersen C, Schmitt V, Semrau S, Sterzing F, Streblow J, Wendt T, Wittig A, Guckenberger M
INT J RADIAT ONCOL. 2016;94(4):841-9.
Cdc45 is limiting for replication initiation in humans
Köhler C, Koalick D, Fabricius A, Parplys A, Borgmann K, Pospiech H, Grosse F
CELL CYCLE. 2016;15(7):974-85.
Radiosensitization of HNSCC cells by EGFR inhibition depends on the induction of cell cycle arrests
Kriegs M, Kasten-Pisula U, Riepen B, Hoffer K, Struve N, Myllynen L, Braig F, Binder M, Rieckmann T, Grénman R, Petersen C, Dikomey E, Rothkamm K
ONCOTARGET. 2016;7(29):45122-45133.
Situation of young radiation oncologists, medical physicists and radiation biologists in German-speaking countries: Results from a web-based survey of the Young DEGRO working group
Krug D, Baumann R, Rieckmann T, Fokas E, Gauer T, Niyazi M
STRAHLENTHER ONKOL. 2016;192(8):507-15.
Comparison of nine prognostic scores in patients with brain metastases of breast cancer receiving radiotherapy of the brain
Laakmann E, Riecke K, Goy Y, Kersten J, Krüll A, Müller V, Petersen C, Witzel I
J CANCER RES CLIN. 2016;142(1):325-32.
Molecular targeting in combination with platinum-based chemoradiation in head and neck cancer treatment
Möckelmann N, Kriegs M, Lörincz B, Busch C, Knecht R
HEAD NECK-J SCI SPEC. 2016;38(Suppl 1):E2173-81.
Effect of sorafenib on cisplatin-based chemoradiation in head and neck cancer cells
Möckelmann N, Rieckmann T, Busch C, Becker B, Gleißner L, Hoffer K, Omniczynski M, Steinmeister L, Laban S, Grénman R, Petersen C, Rothkamm K, Dikomey E, Knecht R, Kriegs M
ONCOTARGET. 2016;7(17):23542-51.
Correlation between the radiation responses of fibroblasts cultured from individual patients and the risk of late reaction after breast radiotherapy
Nuta O, Somaiah N, Boyle S, Chua M, Gothard L, Yarnold J, Rothkamm K, Herskind C
CANCER LETT. 2016;374(2):324-30.
PARP-Inhibition - eine neue Therapieoption bei Prostatakarzinomen mit DNA-Reparaturdefizienz
Oing C, Mansour W, Bokemeyer C
InFo Onkologie. 2016;(02):2-3.
TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress
Pai G, Zielinski A, Koalick D, Ludwig K, Wang Z, Borgmann K, Pospiech H, Rubio I
ONCOTARGET. 2016;7(51):85365-85380.
Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair
Penterling C, Drexler G, Böhland C, Stamp R, Wilke C, Braselmann H, Caldwell R, Reindl J, Girst S, Greubel C, Siebenwirth C, Mansour Khalfallah W, Borgmann K, Dollinger G, Unger K, Friedl A
PLOS ONE. 2016;11(6):e0156599.
Möglichkeiten der lokal-ablativen Bestrahlung (SBRT) bei metastasiertem kolorektalem Karzinom
Petersen C, Gauer T
ONKOLOGE. 2016;22(2):115-120.
Detrimental social interactions predict loss of dignity among patients with cancer
Philipp R, Mehnert A, Lehmann C, Oechsle K, Bokemeyer C, Krüll A, Vehling S
SUPPORT CARE CANCER. 2016;24(6):2751-8.
The benefit of abdominal sonography and chest X-ray for staging oral squamous cell carcinomas in stages UICC I and II
Precht C, Baustian S, Tribius S, Schöllchen M, Hanken H, Smeets R, Heiland M, Gröbe A
J CRANIO MAXILL SURG. 2016;44(2):186-90.
Forecasting Survival Probabilities After Radiotherapy of Metastatic Epidural Spinal Cord Compression from Colorectal Cancer in the Elderly
Rades D, Bartscht T, Janssen S, Bajrovic A, Segedin B, Schild S
ANTICANCER RES. 2016;36(4):1829-33.
A Survival Score for Patients Receiving Stereotactic Radiosurgery Alone for Brain Metastases from Breast Cancer
Rades D, Dziggel L, Janssen S, Blanck O, Hornung D, Schild S
ANTICANCER RES. 2016;36(3):1073-6.
Overall Survival After Whole-Brain Radiation Therapy for Intracerebral Metastases from Testicular Cancer
Rades D, Dziggel L, Veninga T, Bajrovic A, Schild S
ANTICANCER RES. 2016;36(9):4817-9.
A Total Radiation Dose of 70 Gy Is Required After Macroscopically Incomplete Resection of Squamous Cell Carcinoma of the Head and Neck
Rades D, Janssen S, Bajrovic A, Strojan P, Schild S
ANTICANCER RES. 2016;36(6):2989-92.
Comparison of 20×2 Gy and 12×3 Gy for Whole-brain Irradiation of Multiple Brain Metastases from Malignant Melanoma
Rades D, Sehmisch L, Bajrovic A, Janssen S, Schild S
IN VIVO. 2016;30(6):917-919.
Chemoradiation of locally advanced squamous cell carcinoma of the head-and-neck (LASCCHN): Is 20mg/m(2) cisplatin on five days every four weeks an alternative to 100mg/m(2) cisplatin every three weeks?
Rades D, Seidl D, Janssen S, Bajrovic A, Hakim S, Wollenberg B, Karner K, Strojan P, Schild S
ORAL ONCOL. 2016;59:67-72.
Do we need 5-FU in addition to cisplatin for chemoradiation of locally advanced head-and-neck cancer?
Rades D, Seidl D, Janssen S, Bajrovic A, Hakim S, Wollenberg B, Schild S
ORAL ONCOL. 2016;57:40-5.
Comparison of weekly administration of cisplatin versus three courses of cisplatin 100 mg/m(2) for definitive radiochemotherapy of locally advanced head-and-neck cancers
Rades D, Seidl D, Janssen S, Bajrovic A, Karner K, Strojan P, Schild S
BMC CANCER. 2016;16:437.
Radiochemotherapy for locally advanced squamous cell carcinoma of the head and neck: Higher-dose cisplatin every 3 weeks versus cisplatin/5-fluorouracil every 4 weeks
Rades D, Strojan P, Seidl D, Janssen S, Bajrovic A, Kazic N, Hakim S, Wollenberg B, Schild S
J CRANIO MAXILL SURG. 2016;44(9):1436-40.
Evaluation of the 'Jumping to conclusions' bias in different subgroups of the at-risk mental state: from cognitive basic symptoms to UHR criteria
Rausch F, Eisenacher S, Elkin H, Englisch S, Kayser S, Striepens N, Lautenschlager M, Heinz A, Gudlowski Y, Janssen B, Gaebel W, Michel T, Schneider F, Lambert M, Naber D, Juckel G, Krueger-Oezguerdal S, Wobrock T, Hasan A, Riedel M, Moritz S, Müller H, Klosterkötter J, Bechdolf A, Zink M, Wagner M
PSYCHOL MED. 2016;46(10):2071-81.
Stereotactic body radiotherapy (SBRT) for medically inoperable lung metastases-A pooled analysis of the German working group "stereotactic radiotherapy"
Rieber J, Streblow J, Uhlmann L, Flentje M, Duma M, Ernst I, Blanck O, Wittig A, Boda-Heggemann J, Krempien R, Lohaus F, Klass N, Eble M, Imhoff D, Kahl H, Petersen C, Gerum S, Henkenberens C, Adebahr S, Hass P, Schrade E, Wendt T, Hildebrandt G, Andratschke N, Sterzing F, Guckenberger M
LUNG CANCER. 2016;97:51-8.
Sorafenib inhibits cell growth but fails to enhance radio- and chemosensitivity of glioblastoma cell lines
Riedel M, Struve N, Müller-Goebel J, Köcher S, Petersen C, Dikomey E, Rothkamm K, Kriegs M
ONCOTARGET. 2016;7(38):61988-61995.
Web based scoring is useful for validation and harmonisation of scoring criteria within RENEB
Romm H, Ainsbury E, Barquinero J, Barrios L, Beinke C, Cucu A, Domene M, Filippi S, Monteiro Gil O, Gregoire E, Hadjidekova V, Hatzi V, Lindholm C, M Kacher R, Montoro A, Moquet J, Noditi M, Oestreicher U, Palitti F, Pantelias G, Prieto M, Popescu I, Rothkamm K, Sebastià N, Sommer S, Terzoudi G, Testa A, Wojcik A
INT J RADIAT BIOL. 2016;93(1):110-117.
Prognostic Factors After Definitive Radio(Chemo)Therapy of Locally Advanced Head and Neck Cancer
Seidl D, Janssen S, Strojan P, Bajrovic A, Schild S, Rades D
ANTICANCER RES. 2016;36(5):2523-6.
Correlation between DNA damage responses of skin to a test dose of radiation and late adverse effects of earlier breast radiotherapy
Somaiah N, Chua M, Bourne S, Daley F, A' Hern R, Nuta O, Gothard L, Boyle S, Herskind C, Pearson A, Warrington J, Helyer S, Owen R, Rothkamm K, Yarnold J
RADIOTHER ONCOL. 2016;119(2):244-9.
Real time tracking in liver SBRT: comparison of CyberKnife and Vero by planning structure-based γ-evaluation and dose-area-histograms
Sothmann T, Blanck O, Poels K, Werner R, Gauer T
PHYS MED BIOL. 2016;61(4):1677-91.
Dual targeting of PI3K and MEK enhances the radiation response of K-RAS mutated non-small cell lung cancer
Toulany M, Iida M, Keinath S, Iyi F, Mueck K, Fehrenbacher B, Mansour Khalfallah W, Schaller M, Wheeler D, Rodemann H
ONCOTARGET. 2016;7(28):43746-43761.
Survival and overall treatment time after postoperative radio(chemo)therapy in patients with head and neck cancer
Tribius S, Donner J, Pazdyka H, Münscher A, Gröbe A, Petersen C, Krüll A, Tennstedt P
HEAD NECK-J SCI SPEC. 2016;38(7):1058-1065.
Optimized projection binning for improved helical amplitude- and phase-based 4DCT reconstruction in the presence of breathing irregularity
Werner R, Hofmann C, Gauer T
2016. Medical Imaging 2016: Physics of Medical Imaging. Kontos D, Flohr T, Lo J (Hrsg.). 1. Aufl. SPIE , 978313-1-6.
PARP1 inhibition radiosensitizes HNSCC cells deficient in homologous recombination by disabling the DNA replication fork elongation response
Wurster S, Hennes F, Parplys A, Seelbach J, Mansour Khalfallah W, Zielinski A, Petersen C, Clauditz T, Münscher A, Friedl A, Borgmann K
ONCOTARGET. 2016;7(9):9732-41.
Management of sinonasal undifferentiated carcinoma with intracerebral invasion: Clinical experience at a single institution and review of the literature
Zielinski V, Laban S, Tribius S, Schafhausen P, Veldhoen S, Knecht R, Clauditz T, Muenscher A
ENT-EAR NOSE THROAT. 2016;95(1):23-8.
Involvement of ATM in homologous recombination after end resection and RAD51 nucleofilament formation
Bakr A, Oing C, Köcher S, Borgmann K, Dornreiter I, Petersen C, Dikomey E, Mansour Khalfallah W
NUCLEIC ACIDS RES. 2015;43(6):3154-66.
Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer
Braig F, März M, Schieferdecker A, Schulte A, Voigt M, Stein A, Grob T, Alawi M, Indenbirken D, Kriegs M, Engel E, Vanhoefer U, Grundhoff A, Loges S, Riecken K, Fehse B, Bokemeyer C, Binder M
ONCOTARGET. 2015;6(14):12035-47.
The current role of systemic chemotherapy in the primary treatment of head and neck cancer
Busch C, Tribius S, Schafhausen P, Knecht R
CANCER TREAT REV. 2015;41(3):217-21.
HPV and Radiation Sensitivity
De Costa A, Rieckmann T, Kimple R
2015. Human Papillomavirus (HPV)-Associated Oropharyngeal Cancer. Miller D, Stack M (Hrsg.). 1. Aufl. Springer, 243-289.
Predicting the Risk of New Cerebral Lesions After Stereotactic Radiosurgery (SRS) for Brain Metastases from Breast Cancer
Dziggel L, Dahlke M, Janssen S, Hornung D, Blanck O, Khoa M, Schild S, Rades D
ANTICANCER RES. 2015;35(12):6793-7.
Glucanocellulosic ethanol: the undiscovered biofuel potential in energy crops and marine biomass
Falter C, Zwikowics C, Eggert D, Blümke A, Naumann M, Wolff K, Ellinger D, Reimer R, Voigt C
SCI REP-UK. 2015;5:13722.
Design, performance characteristics and application examples of a new 4D motion platform
Grohmann C, Frenzel T, Werner R, Cremers F
Z MED PHYS. 2015;25(2):156-167.
Is immediate bony microsurgical reconstruction after head and neck tumor ablation associated with a higher rate of local recurrence?
Hanken H, Wilkens R, Riecke B, Al-Dam A, Tribius S, Kluwe L, Smeets R, Heiland M, Eichhorn W, Gröbe A
J CRANIO MAXILL SURG. 2015;43(3):373-5.
Secondary ionisations in a wall-less ion-counting nanodosimeter: quantitative analysis and the effect on the comparison of measured and simulated track structure parameters in nanometric volumes
Hilgers G, Bug M, Gargioni E, Rabus H
EUR PHYS J D. 2015;69(10):239-257.
Radiosensitization of NSCLC cells by EGFR inhibition is the result of an enhanced p53-dependent G1 arrest
Kriegs M, Gurtner K, Can Y, Brammer I, Rieckmann T, Oertel R, Wysocki M, Dorniok F, Gal A, Grob T, Laban S, Kasten-Pisula U, Petersen C, Baumann M, Krause M, Dikomey E
RADIOTHER ONCOL. 2015;115(1):120-7.
Systemic treatment of vulvar cancer
Mahner S, Prieske K, Grimm D, Trillsch F, Prieske S, von Amsberg G, Petersen C, Müller V, Jänicke F, Woelber L
EXPERT REV ANTICANC. 2015;15(6):629-37.
radir package: an R implementation for cytogenetic biodosimetry dose estimation
Moriña D, Higueras M, Puig P, Ainsbury E, Rothkamm K
J RADIOL PROT. 2015;35(3):557-569.
Orthostatic blood pressure test for risk stratification in patients with hypertrophic cardiomyopathy
Münch J, Aydin A, Suling A, Voigt C, Blankenberg S, Patten M
PLOS ONE. 2015;10(6):e0131044.
Role of panendoscopy in identifying and managing risk of head and neck squamous cell carcinoma in routine follow-up: a retrospective clinical evaluation
Münscher A, Sehner S, Taleh J, Tribius S, Möckelmann N, Böttcher A, Gulati A, Dalchow C, Clauditz T, Knecht R
EUR ARCH OTO-RHINO-L. 2015;272(7):1769-75.
Quantitative proteomics unveiled: Regulation of DNA double strand break repair by EGFR involves PARP1
Myllynen L, Kwiatkowski M, Gleißner L, Riepen B, Hoffer K, Wurlitzer M, Petersen C, Dikomey E, Rothkamm K, Schlüter H, Kriegs M
RADIOTHER ONCOL. 2015;116(3):423-30.
Zero-inflated regression models for radiation-induced chromosome aberration data: A comparative study
Oliveira M, Einbeck J, Higueras M, Ainsbury E, Puig P, Rothkamm K
BIOMETRICAL J. 2015;58(2):259-79.
Respiratory surface motion measurement by Microsoft Kinect: implementation and evaluation of a clinical setup
Ortmüller J, Gauer T, Wilms M, Handels H, Werner R
Current Directions in Biomedical Engineering. 2015;1(1):270-273.
High levels of RAD51 perturb DNA replication elongation and cause unscheduled origin firing due to impaired CHK1 activation
Parplys A, Seelbach J, Becker S, Behr M, Wrona A, Jend C, Mansour Khalfallah W, Joosse S, Stuerzbecher H, Pospiech H, Petersen C, Dikomey E, Borgmann K
CELL CYCLE. 2015;14(19):3190-202.
Geographical and anatomical influences on human papillomavirus prevalence diversity in head and neck squamous cell carcinoma in Germany
Quabius E, Haag J, Kühnel A, Henry H, Hoffmann A, Görögh T, Hedderich J, Evert M, Beule A, Maune S, Knecht R, Óvári A, Durisin M, Hoppe F, Tribius S, Röcken C, Ambrosch P, Hoffmann M
INT J ONCOL. 2015;46(1):414-22.
Defining the Optimal Dose of Stereotactic Radiosurgery for Treating Cerebral Metastases in Elderly Patients
Rades D, Dahlke M, Dziggel L, Janssen S, Bajrovic A, Trang N, Khoa M, Schild S
ANTICANCER RES. 2015;35(10):5701-4.
A New Predictive Tool for Optimization of the Treatment of Brain Metastases from Colorectal Cancer After Stereotactic Radiosurgery
Rades D, Dahlke M, Gebauer N, Bartscht T, Hornung D, Trang N, Phuong P, Khoa M, Gliemroth J
ANTICANCER RES. 2015;35(10):5515-8.
A new instrument for estimating the survival of patients with metastatic epidural spinal cord compression from esophageal cancer
Rades D, Huttenlocher S, Bajrovic A, Karstens J, Bartscht T
RADIOTHER ONCOL. 2015;49(1):86-90.
A new tool to predict survival after radiosurgery alone for newly diagnosed cerebral metastases
Rades D, Huttenlocher S, Dziggel L, Blanck O, Hornung D, Mai K, Ngo T, Van Pham T, Schild S
Asian Pac J Cancer Prev. 2015;16(7):2967-70.
A new tool predicting survival after radiosurgery alone for one or two cerebral metastases from lung cancer
Rades D, Huttenlocher S, Dziggel L, Khoa M, Van Thai P, Hornung D, Schild S
LUNG. 2015;193(2):299-302.
Impact of stereotactic radiosurgery dose on control of cerebral metastases from renal cell carcinoma
Rades D, Huttenlocher S, Gebauer N, Hornung D, Trang N, Khoa M, Schild S
ANTICANCER RES. 2015;35(6):3571-4.
Number of cerebral lesions predicts freedom from new brain metastases after radiosurgery alone in lung cancer patients
Rades D, Huttenlocher S, Khoa M, Thai P, Hornung D, Schild S
ONCOL LETT. 2015;10(2):1109-1112.
Radiosurgery with 20 Gy provides better local contol of 1-3 brain metastases from breast cancer than with lower doses.
Rades D, Huttenlocher S, Rudat V, Hornung D, Blanck O, Phuong P, Khoa M, Schild S, Fischer D
ANTICANCER RES. 2015;35(1):333-336.
A matched-pair analysis comparing 5x4 Gy and 10x3 Gy for metastatic spinal cord compression (MSCC) in patients with favorable survival prognoses
Rades D, Huttenlocher S, Veninga T, Bajrovic A, Bremer M, Rudat V, Schild S
RADIAT ONCOL. 2015;10:90.
Personalized Radiotherapeutic Approaches for Elderly Patients with Epidural Cord Compression from Gastric Cancer
Rades D, Schild S, Bajrovic A, Janssen S, Bartscht T
IN VIVO. 2015;30(1):69-72.
Association between SNPs in defined functional pathways and risk of early or late toxicity as well as individual radiosensitivity
Reuther S, Szymczak S, Raabe A, Borgmann K, Ziegler A, Petersen C, Dikomey E, Hoeller U
STRAHLENTHER ONKOL. 2015;191(1):59-66.
DNA damage foci: Meaning and significance
Rothkamm K, Barnard S, Moquet J, Ellender M, Rana Z, Burdak-Rothkamm S
ENVIRON MOL MUTAGEN. 2015;56(6):491-504.
Directed Alternative Splicing in Nijmegen Breakage Syndrome: Proof of Principle Concerning Its Therapeutical Application
Salewsky B, Hildebrand G, Rothe S, Parplys A, Radszewski J, Kieslich M, Wessendorf P, Krenzlin H, Borgmann K, Nussenzweig A, Sperling K, Digweed M
MOL THER. 2015;24(1):117-124.
Additional androgen deprivation makes the difference: Biochemical recurrence-free survival in prostate cancer patients after HDR brachytherapy and external beam radiotherapy
Schiffmann J, Lesmana H, Tennstedt P, Beyer B, Boehm K, Platz V, Tilki D, Salomon G, Petersen C, Krüll A, Graefen M, Schwarz R
STRAHLENTHER ONKOL. 2015;191(4):330-337.
Various regimens for prophylactic treatment of patients with haemophilia
Schwarz R, Ljung R, Tedgård U
EUR J HAEMATOL. 2015;94 :11-6.
Where Do We Look for Markers of Radiotherapy Fraction Size Sensitivity?
Somaiah N, Rothkamm K, Yarnold J
CLIN ONCOL-UK. 2015;27(10):570-578.
5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair
Srinivas U, Dyczkowski J, Beißbarth T, Gaedcke J, Mansour Khalfallah W, Borgmann K, Dobbelstein M
ONCOTARGET. 2015;6(14):12574-86.
EGFRvIII does not affect radiosensitivity with or without gefitinib treatment in glioblastoma cells
Struve N, Riedel M, Schulte A, Rieckmann T, Grob T, Gal A, Rothkamm K, Lamszus K, Petersen C, Dikomey E, Kriegs M
ONCOTARGET. 2015;6(32):33867-77.
Groupwise Registration for Robust Motion Field Estimation in Artifact-Affected 4D CT Images
Tack A, Kobayashi Y, Gauer T, Schlaefer A, Werner R
2015. MICCAI Workshop on Imaging and Computer Assistance in Radiation Therapy Workshop (ICART). 1. Aufl. 18-25.
Residual deficits in quality of life one year after intensity-modulated radiotherapy for patients with locally advanced head and neck cancer: Results of a prospective study
Tribius S, Raguse M, Voigt C, Münscher A, Gröbe A, Petersen C, Krüll A, Bergelt C, Singer S
STRAHLENTHER ONKOL. 2015.
Reference geometry-based detection of (4D-)CT motion artifacts: a feasibility study
Werner R, Gauer T
2015. Medical Imaging 2015. Ourselin S, Styner M (Hrsg.). 1. Aufl. SPIE , 0S1-7.
EURAMOS-1, an international randomised study for osteosarcoma: results from pre-randomisation treatment
Whelan J, Bielack S, Marina N, Smeland S, Jovic G, Hook J, Krailo M, Anninga J, Butterfass-Bahloul T, Böhling T, Calaminus G, Capra M, Deffenbaugh C, Dhooge C, Eriksson M, Flanagan A, Gelderblom H, Goorin A, Gorlick R, Gosheger G, Grimer R, Hall K, Helmke K, Hogendoorn P, Jundt G, Kager L, Kuehne T, Lau C, Letson G, Meyer J, Meyers P, Morris C, Mottl H, Nadel H, Nagarajan R, Randall R, Schomberg P, Schwarz R, Teot L, Sydes M, Bernstein M
ANN ONCOL. 2015;26(2):407-14.
Holmium laser enucleation of the prostate is safe in patients with prostate cancer and lower urinary tract symptoms--a retrospective feasibility study
Becker A, Placke A, Kluth L, Schwarz R, Isbarn H, Chun F, Heuer R, Schlomm T, Seiler D, Engel O, Fisch M, Graefen M, Ahyai S
J ENDOUROL. 2014;28(3):335-41.
Proton-impact ionisation cross sections for nanodosimetric track structure simulations
Bug M, Gargioni E, Baek W, Hilgers G, Nettelbeck H, Rosenfeld A, Rabus H
RADIAT PROT DOSIM. 2014;161(1-4):474-7.
Activated leukocyte cell adhesion molecule (ALCAM/CD166) expression in head and neck squamous cell carcinoma (HNSSC)
Clauditz T, von Rheinbaben K, Lebok P, Minner S, Tachezy M, Borgmann K, Knecht R, Sauter G, Wilczak W, Blessmann M, Münscher A
PATHOL RES PRACT. 2014;210(10):649-655.
Partial body irradiation of small laboratory animals with an industrial X-ray tube
Frenzel T, Grohmann C, Schumacher U, Krüll A
Z MED PHYS. 2014;24(4):352-362.
Treatment of children with central nervous system primitive neuroectodermal tumors/pinealoblastomas in the prospective multicentric trial HIT 2000 using hyperfractionated radiation therapy followed by maintenance chemotherapy
Gerber N, von Hoff K, Resch A, Ottensmeier H, Kwiecien R, Faldum A, Matuschek C, Hornung D, Bremer M, Benesch M, Pietsch T, Warmuth-Metz M, Kuehl J, Rutkowski S, Kortmann R
INT J RADIAT ONCOL. 2014;89(4):863-71.
The inhibition of PARP but not EGFR results in the radiosensitization of HPV/p16-positive HNSCC cell lines
Güster J, Weissleder S, Busch C, Kriegs M, Petersen C, Knecht R, Dikomey E, Rieckmann T
RADIOTHER ONCOL. 2014;113(3):345-51.
Comparison of measured and Monte Carlo simulated track structure parameters in nanometric volumes
Hilgers G, Bug M, Gargioni E, Rabus H
RADIAT PROT DOSIM. 2014;161(1-4):441-4.
Exploring spiritual needs and their associated factors in an urban sample of early and advanced cancer patients
Höcker A, Krüll A, Koch-Gromus U, Mehnert A
EUR J CANCER CARE. 2014;23(6):786-94.
Identifying melanoma patients with 1-3 brain metastases who may benefit from whole-brain irradiation in addition to radiosurgery
Huttenlocher S, Sehmisch L, Schild S, Blank O, Hornung D, Rades D
ANTICANCER RES. 2014;34(10):5589-92.
Prognostic role of vascular endothelial growth factor and its receptor-1 in patients with esophageal cancer
Kilic E, Schild S, Thorns C, Bajrovic A, Rades D
ANTICANCER RES. 2014;34(9):5221-6.
Therapie von Kopf-Hals-Karzinomen
Knecht R, Busch C, Lörincz B, Schafhausen P, Tribius S, Heiland M, Jenckel F, Münscher A, Petersen C, Bokemeyer C
Hamb Ärztebl. 2014;8:12-17.
Inhibition of PARP1-dependent end-joining contributes to Olaparib-mediated radiosensitization in tumor cells
Kötter A, Cornils K, Borgmann K, Dahm-Daphi J, Petersen C, Dikomey E, Mansour Khalfallah W
MOL ONCOL. 2014;8(8):1616-25.
Simultaneous cytoplasmic and nuclear protein expression of melanoma antigen-A family and NY-ESO-1 cancer-testis antigens represents an independent marker for poor survival in head and neck cancer
Laban S, Atanackovic D, Luetkens T, Knecht R, Busch C, Freytag M, Spagnoli G, Ritter G, Hoffmann T, Knuth A, Sauter G, Wilczak W, Blessmann M, Borgmann K, Münscher A, Clauditz T
INT J CANCER. 2014.
Strahlentherapie beim Vulva- und Vaginalkarzinom
Petersen C, Goy Y, Krüll A
ONKOLOGE. 2014.
Prostate Cancer
Petersen C, Schwarz R
2014. Decision Tools for Radiation Oncology . Nieder C, Gaspar L (Hrsg.). 1. Aufl. Springer, 231-240.
Biologic factors associated with tumor oxygenation are prognostic in patients with stage III esophageal cancer: long-term results
Rades D, Bajrovic A, Schild S, Thorns C, Kilic E
ANTICANCER RES. 2014;34(8):4351-5.
Metastatic spinal cord compression: a validated survival score for elderly patients
Rades D, Evers J, Bajrovic A, Veninga T, Karstens J, Schild S
STRAHLENTHER ONKOL. 2014;190(10):919-24.
Re-irradiation of spinal cord compression due to metastasis in elderly patients
Rades D, Evers J, Bajrovic A, Veninga T, Schild S
ANTICANCER RES. 2014;34(5):2555-8.
A validated score estimating ambulatory status following radiotherapy of elderly patients for metastatic spinal cord compression
Rades D, Evers J, Rudat V, Bajrovic A, Karstens J, Schild S
BMC CANCER. 2014;14:589.
Do patients with very few brain metastases from breast cancer benefit from whole-brain radiotherapy in addition to radiosurgery?
Rades D, Huttenlocher S, Hornung D, Blanck O, Schild S, Fischer D
RADIAT ONCOL. 2014;9:267.
Neuroonkologie
Rutkowski S, Hornung D, Kordes U, Kammler G, Hagel C, Löbel U, Ebinger M, Rössler J, Resch A, Linhart D
2014. Neuropädiatrie - Evidenzbasierte Therapie. Korinthenberg R, Panteliadis C, Hagel C (Hrsg.). 2. Aufl. München: Elsevier, .
Suitability of markerless EPID tracking for tumor position verification in gated radiotherapy
Serpa M, Baier K, Cremers F, Guckenberger M, Meyer J
MED PHYS. 2014;41(3):031702.
Sequential neoadjuvant chemoradiotherapy (CRT) followed by curative surgery vs. primary surgery alone for resectable, non-metastasized pancreatic adenocarcinoma: NEOPA- a randomized multicenter phase III study (NCT01900327, DRKS00003893)
Tachezy M, Gebauer F, Petersen C, Arnold D, Trepel M, Wegscheider K, Schafhausen P, Bockhorn M, Izbicki J, Yekebas E
BMC CANCER. 2014;14(1):411.
Induktionschemotherapie bei lokal fortgeschrittenen Kopf-Hals-Karzinomen--contra
Tribius S, Petersen C
DEUT MED WOCHENSCHR. 2014;139(41):2081.
Incidental dose to coronary arteries is higher in prone than in supine whole breast irradiation. A dosimetric comparison in adjuvant radiotherapy of early stage breast cancer
Würschmidt F, Stoltenberg S, Kretschmer M, Petersen C
STRAHLENTHER ONKOL. 2014;190(6):563-8.
Molecular radiation biology/oncology at its best:cutting edge research presented at the 13th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology
Baumann M, Bodis S, Dikomey E, van der Kogel A, Overgaard J, Rodemann H, Wouters B
RADIOTHER ONCOL. 2013;108(3):357-61.
Detection of impaired homologous recombination repair in NSCLC cells and tissues
Birkelbach M, Ferraiolo N, Gheorghiu L, Pfäffle H, Daly B, Ebright M, Spencer C, O'Hara C, Whetstine J, Benes C, Sequist L, Zou L, Dahm-Daphi J, Kachnic L, Willers H
J THORAC ONCOL. 2013;8(3):279-86.
Ionization cross section data of nitrogen, methane, and propane for light ions and electrons and their suitability for use in track structure simulations
Bug M, Gargioni E, Nettelbeck H, Baek W, Hilgers G, Rosenfeld A, Rabus H
PHYS REV E. 2013;88(4):043308.
HPV-positive HNSCC cell lines but not primary human fibroblasts are radiosensitized by the inhibition of Chk1
Busch C, Kriegs M, Laban S, Tribius S, Knecht R, Petersen C, Dikomey E, Rieckmann T
RADIOTHER ONCOL. 2013;108(3):495-9.
Expression of insulin-like growth factor II mRNA-binding protein 3 in squamous cell carcinomas of the head and neck
Clauditz T, Busch C, Gontarewicz A, Blessmann M, Tennstedt P, Borgmann K, Tribius S, Sauter G, Dalchow C, Knecht R, Münscher A, Wilczak W
J ORAL PATHOL MED. 2013;42(2):125-32.
Prädiktive Marker für die akute Normalgewebetoxizität bei Bestrahlung von nicht-kleinzelligen Lungenkarzinomen
Dikomey E
STRAHLENTHER ONKOL. 2013;189(9):806-8.
In reply to Kapoor.
Dikomey E, Raabe A, Reuther S
INT J RADIAT ONCOL. 2013;86(3):401.
Immunohistochemical analysis of p16 expression, HPV infection and its prognostic utility in oral squamous cell carcinoma
Gröbe A, Hanken H, Kluwe L, Schöllchen M, Tribius S, Pohlenz P, Clauditz T, Grob T, Simon R, Sauter G, Heiland M, Blessmann M
J ORAL PATHOL MED. 2013;42(9):676-81.
Human papillomavirus infection in head and neck cancer: the role of the secretory leukocyte protease inhibitor.
Hoffmann M, Quabius E, Tribius S, Hebebrand L, Görögh T, Halec G, Kahn T, Hedderich J, Röcken C, Haag J, Waterboer T, Schmitt M, Giuliano A, Kast W
ONCOL REP. 2013;29(5):1962-1968.
A synthetic codon-optimized hepatitis C virus nonstructural 5A DNA vaccine primes polyfunctional CD8+ T cell responses in wild-type and NS5A-transgenic mice
Holmström F, Pasetto A, Nähr V, Brass A, Kriegs M, Hildt E, Broderick K, Chen M, Ahlén G, Frelin L
J IMMUNOL. 2013;190(3):1113-24.
Late recurrence of a pineal germinoma 14 years after radiation and chemotherapy: a case report and review of the literature
Janjetovic S, Bokemeyer C, Fiedler W, Frenzel T, Calaminus G, Honecker F
ONKOLOGIE. 2013;36(6):371-3.
A subset of histone H2B genes produces polyadenylated mRNAs under a variety of cellular conditions
Kari V, Karpiuk O, Tieg B, Kriegs M, Dikomey E, Krebber H, Begus-Nahrmann Y, Johnsen S
PLOS ONE. 2013;8(5):e63745.
Genomic deletion of MAP3K7 at 6q12-22 is associated with early PSA recurrence in prostate cancer and absence of TMPRSS2:ERG fusions
Kluth M, Hesse J, Heinl A, Krohn A, Steurer S, Sirma H, Simon R, Mayer P, Schumacher U, Grupp K, Izbicki J, Pantel K, Dikomey E, Korbel J, Plass C, Sauter G, Schlomm T, Minner S
MODERN PATHOL. 2013;26(7):975-83.
ATM is required for the repair of Topotecan-induced replication-associated double-strand breaks
Köcher S, Spies-Naumann A, Kriegs M, Dahm-Daphi J, Dornreiter I
RADIOTHER ONCOL. 2013;108(3):409-14.
Molecular targeting agents in the context of primary chemoradiation strategies.
Laban S, Busch C, Münscher A, Tribius S, Schafhausen P, Knecht R
HEAD NECK-J SCI SPEC. 2013;35(5):738-746.
Sorafenib sensitizes head and neck squamous cell carcinoma cells to ionizing radiation
Laban S, Steinmeister L, Gleißner L, Grob T, Grénman R, Petersen C, Gal A, Knecht R, Dikomey E, Kriegs M
RADIOTHER ONCOL. 2013;109(2):286-92.
Elevated CD57 and CD95 expressions are associated with lower numbers of CD4⁺ recent thymic emigrants in HIV-1 infected immune responders following antiretroviral treatment
Lu I, Eberhard J, Ahmad F, Bhatnagar N, Behrens G, Jacobs R, Schmidt R, Meyer-Olson D
IMMUNOL LETT. 2013;158(1-2):1-6.
Adjuvant therapy in node-positive vulvar cancer
Mahner S, Trillsch F, Kock L, Rohsbach D, Petersen C, Krüll A, Harter P, Jänicke F, Woelber L
EXPERT REV ANTICANC. 2013;13(7):839-44.
Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma.
Mansour Khalfallah W, Bogdanova N, Kasten-Pisula U, Rieckmann T, Köcher S, Borgmann K, Baumann M, Krause M, Petersen C, Hu H, Gatti R, Dikomey E, Dörk T, Dahm-Daphi J
RADIOTHER ONCOL. 2013;106(1):147-154.
The absence of Ku but not defects in classical non-homologous end-joining is required to trigger PARP1-dependent end-joining
Mansour Khalfallah W, Borgmann K, Petersen C, Dikomey E, Dahm-Daphi J
DNA REPAIR. 2013;12(12):1134-42.
Die wichtigsten Studienergebnisse der primären Radio-Chemo-Therapie von Kopf-Hals-Tumoren: Highlights des ASCO-Meetings 2013
Münscher A, Busch C, Schafhausen P, Tribius S, Knecht R
HNO. 2013;61(11):905-10.
Heterozygous mutations in PALB2 cause DNA replication and damage response defects
Nikkilä J, Parplys A, Pylkäs K, Bose M, Huo Y, Borgmann K, Rapakko K, Nieminen P, Xia B, Pospiech H, Winqvist R
NAT COMMUN. 2013;4:2578.
Optimaler Zeitpunkt für die Operation beim Rektumkarzinom nach neoadjuvanter Radiochemotherapie: Für welche Patienten wäre Warten besser?
Petersen C
STRAHLENTHER ONKOL. 2013;189:904-906.
EGFR-activating mutations correlate with a Fanconi anemia-like cellular phenotype that includes PARP inhibitor sensitivity
Pfäffle H, Wang M, Gheorghiu L, Ferraiolo N, Greninger P, Borgmann K, Settleman J, Benes C, Sequist L, Zou L, Willers H
CANCER RES. 2013;73(20):6254-63.
A validated scoring system to identify long-term survivors after radiotherapy for metastatic spinal cord compression
Rades D, Veninga T, Bajrovic A, Karstens J, Schild S
STRAHLENTHER ONKOL. 2013;189(6):462-6.
No effect of the transforming growth factor β1 promoter polymorphism C-509T on TGFB1 gene expression, protein secretion, or cellular radiosensitivity.
Reuther S, Metzke E, Bonin M, Petersen C, Dikomey E, Raabe A
INT J RADIAT ONCOL. 2013;85(2):460-465.
Effect of irradiation on the expression of DNA repair genes studied in human fibroblasts by real-time qPCR using three methods of reference gene validation
Reuther S, Reiter M, Raabe A, Dikomey E
RADIAT ENVIRON BIOPH. 2013;52(4):463-9.
p53 modulates homologous recombination at I-SceI-induced double-strand breaks through cell-cycle regulation.
Rieckmann T, Kriegs M, Nitsch L, Hoffer K, Rohaly G, Köcher S, Petersen C, Dikomey E, Dornreiter I, Dahm-Daphi J
ONCOGENE. 2013;32(8):968-975.
HNSCC cell lines positive for HPV and p16 possess higher cellular radiosensitivity due to an impaired DSB repair capacity.
Rieckmann T, Tribius S, Grob T, Meyer F, Busch C, Petersen C, Dikomey E, Kriegs M
RADIOTHER ONCOL. 2013;107(2):242-246.
Inactivation of HNSCC cells by 90Y-labeled cetuximab strictly depends on the number of induced DNA double-strand breaks.
Saker J, Kriegs M, Zenker M, Heldt J, Eke I, Pietzsch H, Grénman R, Cordes N, Petersen C, Baumann M, Steinbach J, Dikomey E, Kasten-Pisula U
J NUCL MED. 2013;54(3):416-423.
RAD51 overexpression is a negative prognostic marker for colorectal adenocarcinoma
Tennstedt P, Fresow R, Simon R, Marx A, Terracciano L, Petersen C, Sauter G, Dikomey E, Borgmann K
INT J CANCER. 2013;132(9):2118-26.
Human papilloma virus infection in head and neck cancer.
Tribius S, Hoffmann M
DTSCH ARZTEBL INT. 2013;110(11):1, 184-190.
Xerostomia after radiotherapy. What matters--mean total dose or dose to each parotid gland?
Tribius S, Sommer J, Prosch C, Bajrovic A, Münscher A, Blessmann M, Krüll A, Petersen C, Todorovic M, Tennstedt P
STRAHLENTHER ONKOL. 2013;189(3):216-222.
Management of patients with vulvar cancer: a perspective review according to tumour stage
Woelber L, Trillsch F, Kock L, Grimm D, Petersen C, Choschzick M, Jänicke F, Mahner S
THER ADV MED ONCOL. 2013;5(3):183-92.
Osteosarcoma of the mobile spine
Zils K, Bielack S, Wilhelm M, Werner M, Schwarz R, Windhager R, Hofmann-Wackersreuther G, Andus T, Kager L, Kuehne T, Reichardt P, von Kalle T
ANN ONCOL. 2013;24(8):2190-5.
Will SNPs be useful predictors of normal tissue radiosensitivity in the future?
Andreassen C, Dikomey E, Parliament M, West C
RADIOTHER ONCOL. 2012;105(3):283-288.
Differential elastic and total electron scattering cross sections of tetrahydrofuran
Baek W, Bug M, Rabus H, Gargioni E, Grosswendt B
PHYS REV A. 2012;86(3):32702.
Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity.
Barnett G, Elliott R, Alsner J, Andreassen C, Abdelhay O, Burnet N, Chang-Claude J, Coles C, Gutiérrez-Enríquez S, Fuentes-Raspall M, Alonso-Muñoz M, Kerns S, Raabe A, Symonds R, Seibold P, Talbot C, Wenz F, Wilkinson J, Yarnold J, Dunning A, Rosenstein B, West C, Bentzen S
RADIOTHER ONCOL. 2012;105(3):289-295.
[Prediction of the reaction of normal tissue and tumor cells to radiotherapy].
Dikomey E, Dahm-Daphi J, Distel L
STRAHLENTHER ONKOL. 2012;188 Suppl 3:304-307.
Prognostic factors for different outcomes in patients with metastatic spinal cord compression from cancer of unknown primary.
Douglas S, Huttenlocher S, Bajrovic A, Rudat V, Schild S, Rades D
BMC CANCER. 2012;12:261.
Tumorerfassung
Frenzel T, Honecker F, Krüll A, Petersen C, Yekebas E
2012. Tumorerfassung: mit Erfassungsbögen und Leitlinien für die interdiszipl. Diagnostik und Therapie. Thieme-Verlag Stuttgart: 1-328.
Scattering effects of irradiation on surroundings calculated for a small dental implant.
Friedrich R, Todorovic M, Heiland M, Scheuer H, Krüll A
ANTICANCER RES. 2012;32(5):2043-2046.
Humane Papillomvirusinfektionen im Kopf-Hals-Bereich im öffentlichen Bewusstsein: Mahnung zu Präzision in Diagnostik und Öffentlichkeitsarbeit
Hoffmann M, Hoffmann A, Tribius S
HNO. 2012;60(11):968-973.
HPV DNA, E6*I-mRNA expression and p16INK4A immunohistochemistry in head and neck cancer - how valid is p16INK4A as surrogate marker?
Hoffmann M, Tribius S, Quabius E, Henry H, Pfannenschmidt S, Burkhardt C, Görögh T, Halec G, Hoffmann A, Kahn T, Röcken C, Haag J, Waterboer T, Schmitt M
CANCER LETT. 2012;323(1):88-96.
Late complications after radiotherapy for prostate cancer.
Jung H, Beck-Bornholdt H, Svoboda V, Alberti W, Herrmann T
STRAHLENTHER ONKOL. 2012;188(11):965-974.
Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase.
Köcher S, Rieckmann T, Rohaly G, Mansour W, Dikomey E, Dornreiter I, Dahm-Daphi J
NUCLEIC ACIDS RES. 2012;40(17):8336-8347.
Neue Aspekte der primären Radiochemotherapie bei Kopf-Hals-Tumoren. Highlights vom ASCO-Kongress 2011
Laban S, Wang C, Knecht R, Tribius S, Münscher A
HNO. 2012;60(5):393-7.
[New aspects of primary radiochemotherapy in head and neck cancer : Highlights from the 2011 ASCO Congress].
Laban S, Wang C, Knecht R, Tribius S, Münscher A
HNO. 2012;60(5):393-397.
Die wichtigsten Studienergebnisse der primären Radiochemotherapie von Kopf-Hals-Tumoren: Highlights vom ASCO-Meeting 2012
Laban S, Zielinski V, Busch C, Münscher A, Schafhausen P, Tribius S, Knecht R
HNO. 2012;60(11):962-967.
Effect of a static magnetic field on nanodosimetric quantities in a DNA volume.
Lazarakis P, Bug M, Gargioni E, Guatelli S, Incerti S, Rabus H, Rosenfeld A
INT J RADIAT BIOL. 2012;88(1-2):183-188.
Comparison of nanodosimetric parameters of track structure calculated by the Monte Carlo codes Geant4-DNA and PTra.
Lazarakis P, Bug M, Gargioni E, Guatelli S, Rabus H, Rosenfeld A
PHYS MED BIOL. 2012;57(5):1231-1250.
[Psychosocial predictors of utilization of medical rehabilitation services among prostate cancer patients].
Lehmann C, Beierlein V, Hagen-Aukamp C, Kerschgens C, Rhee M, Frühauf S, Otto J, Graefen M, Krüll A, Berger D, Koch U, Bergelt C
REHABILITATION. 2012;51(3):160-170.
SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response.
Mund A, Schubert T, Staege H, Kinkley S, Reumann K, Kriegs M, Fritsch L, Battisti V, Ait-Si-Ali S, Hoffbeck A, Soutoglou E, Will H
NUCLEIC ACIDS RES. 2012;40(22):11363-11379.
DNA damage by X-rays and their impact on replication processes.
Parplys A, Petermann E, Petersen C, Dikomey E, Borgmann K
RADIOTHER ONCOL. 2012;102(3):466-471.
Association of single nucleotide polymorphisms in the genes ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with risk of severe erythema after breast conserving radiotherapy.
Raabe A, Derda K, Reuther S, Symczak S, Borgmann K, Hoeller U, Ziegler A, Petersen C, Dikomey E
RADIAT ONCOL. 2012;7(1):65.
Prognostic factors and a survival score for patients with metastatic spinal cord compression from colorectal cancer.
Rades D, Douglas S, Huttenlocher S, Veninga T, Bajrovic A, Rudat V, Schild S
STRAHLENTHER ONKOL. 2012;188(12):1114-1118.
A survival score for patients with metastatic spinal cord compression from prostate cancer.
Rades D, Douglas S, Veninga T, Bajrovic A, Stalpers L, Hoskin P, Rudat V, Schild S
STRAHLENTHER ONKOL. 2012;188(9):802-806.
Metastatic spinal cord compression in non-small cell lung cancer patients. Prognostic factors in a series of 356 patients.
Rades D, Douglas S, Veninga T, Bajrovic A, Stalpers L, Hoskin P, Rudat V, Schild S
STRAHLENTHER ONKOL. 2012;188(6):472-476.
Prognostic factors for local control and survival in patients with spinal cord compression from myeloma.
Rades D, Douglas S, Veninga T, Poortmans P, Bajrovic A, Hoskin P, Rudat V, Schild S
STRAHLENTHER ONKOL. 2012;188(7):628-631.
Prognostic factors in a series of 504 breast cancer patients with metastatic spinal cord compression.
Rades D, Douglas S, Veninga T, Stalpers L, Bajrovic A, Rudat V, Schild S
STRAHLENTHER ONKOL. 2012;188(4):340-345.
Impact of zoledronic acid on control of metastatic spinal cord compression.
Rades D, Hakim S, Bajrovic A, Karstens J, Veninga T, Rudat V, Schild S
STRAHLENTHER ONKOL. 2012;188(10):910-916.
Single brain metastasis: radiosurgery alone compared with radiosurgery plus up-front whole-brain radiotherapy.
Rades D, Hornung D, Veninga T, Schild S, Gliemroth J
CANCER-AM CANCER SOC. 2012;118(11):2980-2985.
Do elderly patients benefit from surgery in addition to radiotherapy for treatment of metastatic spinal cord compression?
Rades D, Huttenlocher S, Evers J, Bajrovic A, Karstens J, Rudat V, Schild S
STRAHLENTHER ONKOL. 2012;188(5):424-430.
Single brain metastasis: whole-brain irradiation plus either radiosurgery or neurosurgical resection.
Rades D, Veninga T, Hornung D, Wittkugel O, Schild S, Gliemroth J
CANCER-AM CANCER SOC. 2012;118(4):1138-1144.
Fully automated interpretation of ionizing radiation-induced γH2AX foci by the novel pattern recognition system AKLIDES(®).
Runge R, Hiemann R, Wendisch M, Kasten-Pisula U, Storch K, Zoephel K, Fritz C, Roggenbuck D, Wunderlich G, Conrad K, Kotzerke J
INT J RADIAT BIOL. 2012;88(5):439-447.
Neutron radiotherapy in South Africa: neutron radiotherapy should continue.
Sauerwein W, Engenhart-Cabillic R, Forman J, Guelette J, Hachem S, Jones D, Krüll A, Lukas P, Mandrillon P, Petry W, Rosenberg I, Venimmen F, Welsh J
SAMJ S AFR MED J. 2012;102(5):269-70; author reply 270-1.
HPV status in patients with head and neck of carcinoma of unknown primary site: HPV, tobacco smoking, and outcome.
Tribius S, Hoffmann A, Bastrop S, Görögh T, Haag J, Röcken C, Clauditz T, Grob T, Wilczak W, Tennstedt P, Borcherding A, Petersen C, Hoffmann M
ORAL ONCOL. 2012;48(11):1178-1184.
Global quality of life during the acute toxicity phase of multimodality treatment for patients with head and neck cancer: can we identify patients most at risk of profound quality of life decline?
Tribius S, Reemts E, Prosch C, Raguse M, Petersen C, Krüll A, Singer S, Bergelt C
ORAL ONCOL. 2012;48(9):898-904.
Is advanced cancer associated with demoralization and lower global meaning? The role of tumor stage and physical problems in explaining existential distress in cancer patients.
Vehling S, Lehmann C, Oechsle K, Bokemeyer C, Krüll A, Koch-Gromus U, Mehnert A
PSYCHO-ONCOLOGY. 2012;21(1):54-63.
Towards Accurate Dose Accumulation for Step-&-Shoot IMRT: Impact of Weighting Schemes and Temporal Image Resolution on the Estimation of Dosimetric Motion Effects.
Werner R, Ehrhardt J, Schmidt-Richberg A, Albers D, Frenzel T, Petersen C, Cremers F, Handels H
Z MED PHYS. 2012;22(2):109-122.
Prognostic role of lymph node metastases in vulvar cancer and implications for adjuvant treatment
Wölber L, Zu Eulenburg C, Choschzick M, Krüll A, Petersen C, Gieseking F, Jänicke F, Mahner S
INT J GYNECOL CANCER. 2012;22(3):503-508.
Contrast-Enhanced [(18)F]fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography for Staging and Radiotherapy Planning in Patients with Anal Cancer.
Bannas P, Weber C, Adam G, Frenzel T, Derlin T, Mester J, Klutmann S
INT J RADIAT ONCOL. 2011;81(2):445-451.
Cohesin phosphorylation and mobility of SMC1 at ionizing radiation-induced DNA double-strand breaks in human cells
Bauerschmidt C, Woodcock M, Stevens D, Hill M, Rothkamm K, Helleday T
EXP CELL RES. 2011;317(3):330-7.
Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL-positive CML cells.
Brassat U, Balabanov S, Bali D, Dierlamm J, Balabanov M, Hartmann U, Sirma H, Günes C, Wege H, Fehse B, Gontarewicz A, Dikomey E, Borgmann K, Brümmendorf T
EXP HEMATOL. 2011;39(1):62-66.
Tomotherapy in locally advanced head and neck cancer-does it reduce xerostomia?
Goy Y, Prosch C, Bajrovic A, Matnjani G, Krüll A, Petersen C, Albers D, Rapp W, Tribius S
RADIOTHER ONCOL. 2011;98(Suppl. 1):S34.
FANCD2 but not FANCA promotes cellular resistance to type II topoisomerase poisons.
Kachnic L, Li L, Fournier L, Ferraiolo N, Dahm-Daphi J, Borgmann K, Willers H
CANCER LETT. 2011;305(1):86-93.
Cellular and tumor radiosensitivity is correlated to epidermal growth factor receptor protein expression level in tumors without EGFR amplification.
Kasten-Pisula U, Saker J, Eicheler W, Krause M, Yaromina A, Meyer-Staeckling S, Scherkl B, Kriegs M, Brandt B, Grénman R, Petersen C, Baumann M, Dikomey E
INT J RADIAT ONCOL. 2011;80(4):1181-1188.
Ectopic craniopharyngioma.
Kordes U, Flitsch J, Hagel C, Goebell E, Schwarz R, Herberhold T, von Bueren A, Rutkowski S, Müller H
KLIN PADIATR. 2011;223(3):176-177.
Bone marrow-derived progenitor cells do not contribute to podocyte turnover in the puromycin aminoglycoside and renal ablation models in rats.
Meyer-Schwesinger C, Lange C, Bröcker V, Agustian P, Putri A, Lehmann U, Raabe A, Brinkmeyer M, Kobayashi E, Schiffer M, Büsche G, Kreipe H, Thaiss F, Becker J
AM J PATHOL. 2011;178(2):494-499.
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.
Moyal L, Lerenthal Y, Gana-Weisz M, Mass G, So S, Wang S, Eppink B, Chung Y, Shalev G, Shema E, Shkedy D, Smorodinsky N, van Vliet N, Kuster B, Mann M, Ciechanover A, Dahm-Daphi J, Kanaar R, Hu M, Chen D, Oren M, Shiloh Y
MOL CELL. 2011;41(5):529-542.
In tumor cells regulation of DNA double strand break repair through EGF receptor involves both NHEJ and HR and is independent of p53 and K-Ras status.
Myllynen L, Rieckmann T, Dahm-Daphi J, Kasten-Pisula U, Petersen C, Dikomey E, Kriegs M
RADIOTHER ONCOL. 2011;101(1):147-151.
Late Toxicity of Radiotherapy: A Problem or a Challenge for the Radiation Oncologist?
Petersen C, Würschmidt F
BREAST CARE. 2011;6(5):369-374.
Dose escalation for metastatic spinal cord compression in patients with relatively radioresistant tumors.
Rades D, Freundt K, Meyners T, Bajrovic A, Basic H, Karstens J, Adamietz I, Wildfang I, Rudat V, Schild S, Dunst J
INT J RADIAT ONCOL. 2011;80(5):1492-1497.
Surgery followed by radiotherapy versus radiotherapy alone for metastatic spinal cord compression from unfavorable tumors.
Rades D, Huttenlocher S, Bajrovic A, Karstens J, Adamietz I, Kazic N, Rudat V, Schild S
INT J RADIAT ONCOL. 2011;81(5):861-868.
Comparison of four cisplatin-based radiochemotherapy regimens for nonmetastatic stage III/IV squamous cell carcinoma of the head and neck.
Rades D, Kronemann S, Meyners T, Bohlen G, Tribius S, Kazic N, Schroeder U, Hakim S, Schild S, Dunst J
INT J RADIAT ONCOL. 2011;80(4):1037-1044.
Final results of a prospective study comparing the local control of short-course and long-course radiotherapy for metastatic spinal cord compression.
Rades D, Lange M, Veninga T, Stalpers L, Bajrovic A, Adamietz I, Rudat V, Schild S
INT J RADIAT ONCOL. 2011;79(2):524-530.
Comparison of radiochemotherapy alone to surgery plus radio(chemo)therapy for non-metastatic stage III/IV squamous cell carcinoma of the head and neck: A matched-pair analysis.
Rades D, Meyners T, Kazic N, Bajrovic A, Rudat V, Schild S
STRAHLENTHER ONKOL. 2011;187(9):541-547.
Radiochemotherapy versus surgery plus radio(chemo)therapy for stage T3/T4 larynx and hypopharynx cancer - results of a matched-pair analysis.
Rades D, Schroeder U, Bajrovic A, Schild S
EUR J CANCER. 2011;47(18):2729-2734.
Microdosimetric assessment of the radiation quality of a therapeutic proton beam: comparison between numerical simulation and experimental measurements.
Rollet S, Colautti P, Grosswendt B, Herault J, Wind M, Gargioni E, Beck P, Latocha M, Moro D
RADIAT PROT DOSIM. 2011;143(2-4):445-449.
ATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells.
Sirbu B, Lachmayer S, Wülfing V, Marten L, Clarkson K, Lee L, Gheorghiu L, Zou L, Powell S, Dahm-Daphi J, Willers H
PLOS ONE. 2011;6(8):23053.
Intensity-modulated radiotherapy versus conventional and 3D conformal radiotherapy in patients with head and neck cancer: is there a worthwhile quality of life gain?
Tribius S, Bergelt C
CANCER TREAT REV. 2011;37(7):511-519.
Impact of HPV status on treatment of squamous cell cancer of the oropharynx: what we know and what we need to know.
Tribius S, Ihloff A, Rieckmann T, Petersen C, Hoffmann M
CANCER LETT. 2011;304(2):71-79.
Global meaning and meaning-related life attitudes: exploring their role in predicting depression, anxiety, and demoralization in cancer patients.
Vehling S, Lehmann C, Oechsle K, Bokemeyer C, Krüll A, Koch-Gromus U, Mehnert A
SUPPORT CARE CANCER. 2011;19(4):513-520.
EGF receptor inhibition radiosensitizes NSCLC cells by inducing senescence in cells sustaining DNA double-strand breaks.
Wang M, Morsbach F, Sander D, Gheorghiu L, Nanda A, Benes C, Kriegs M, Krause M, Dikomey E, Baumann M, Dahm-Daphi J, Settleman J, Willers H
CANCER RES. 2011;71(19):6261-6269.
Prognostic value of pathological resection margin distance in squamous cell cancer of the vulva.
Wölber L, Choschzick M, Zu Eulenburg C, Hager M, Jänicke F, Gieseking F, Kock L, Henningsen M, Petersen C, Schwarz J, Mahner S
ANN SURG ONCOL. 2011;18(13):3811-3818.
Clinical management of primary vulvar cancer.
Wölber L, Kock L, Gieseking F, Petersen C, Trillsch F, Choschzick M, Jänicke F, Mahner S
EUR J CANCER. 2011;47(15):2315-2321.
[18F]fluoroethylcholine-PET/CT imaging for radiation treatment planning of recurrent and primary prostate cancer with dose escalation to PET/CT-positive lymph nodes.
Würschmidt F, Petersen C, Wahl A, Dahle J, Kretschmer M
RADIAT ONCOL. 2011;6:44.
Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin
Bauerschmidt C, Arrichiello C, Burdak-Rothkamm S, Woodcock M, Hill M, Stevens D, Rothkamm K
NUCLEIC ACIDS RES. 2010;38(2):477-87.
The potential role of G2- but not of G0-radiosensitivity for predisposition of prostate cancer.
Borgmann K, Raabe A, Reuther S, Szymczak S, Schlomm T, Isbarn H, Gomolka M, Busjahn A, Bonin M, Ziegler A, Dikomey E
RADIOTHER ONCOL. 2010;96(1):19-24.
Effect of a magnetic field on the track structure of low-energy electrons: a Monte Carlo study
Bug M, Gargioni E, Guatelli S, Incerti S, Rabus H, Schulte R, Rosenfeld A
EUR PHYS J D. 2010;60(1):85-92.
[Determination of DNA damage in vitro].
Dikomey E
NUKLEARMED-NUCL MED. 2010;49(1):64-68.
Targeting DNA double-strand break repair: is it the right way for sensitizing cells to 5-fluorouracil?
El-Awady R, Saleh E, Dahm-Daphi J
ANTI-CANCER DRUG. 2010;21(3):277-287.
Commissioning of a double-focused micro multileaf collimator (muMLC).
Fischer M, Todorovic M, Drud E, Cremers F
J APPL CLIN MED PHYS. 2010;11(2):3131.
Radiotherapy for oligometastatic disease in patients with spinal cord compression (MSCC) from relatively radioresistant tumors.
Freundt K, Meyners T, Bajrovic A, Basic H, Karstens J, Adamietz I, Rudat V, Schild S, Dunst J, Rades D
STRAHLENTHER ONKOL. 2010;186(4):218-223.
Simulation of scattering effects of irradiation on surroundings using the example of titanium dental implants: a Monte Carlo approach.
Friedrich R, Todorovic M, Krüll A
ANTICANCER RES. 2010;30(5):1727-1730.
Comparison of electron IMRT to helical photon IMRT and conventional photon irradiation for treatment of breast and chest wall tumours.
Gauer T, Engel K, Kiesel A, Albers D, Rades D
RADIOTHER ONCOL. 2010;94(3):313-318.
[HPV infection in head and neck squamous cell carcinoma (HNSCC). Highlights from ASCO 2010].
Ihloff A, Knecht R, Tribius S
HNO. 2010;58(12):1163-1167.
Human papilloma virus in locally advanced stage III/IV squamous cell cancer of the oropharynx and impact on choice of therapy.
Ihloff A, Petersen C, Hoffmann M, Knecht R, Tribius S
ORAL ONCOL. 2010;46(10):705-711.
The epidermal growth factor receptor modulates DNA double-strand break repair by regulating non-homologous end-joining.
Kriegs M, Kasten-Pisula U, Rieckmann T, Holst K, Saker J, Dahm-Daphi J, Dikomey E
DNA REPAIR. 2010;9(8):889-897.
Long-term follow-up of an intensified myeloablative conditioning regimen with in vivo T cell depletion followed by allografting in patients with advanced multiple myeloma.
Kröger N, Einsele H, Derigs G, Wandt H, Krüll A, Zander A
BIOL BLOOD MARROW TR. 2010;16(6):861-864.
The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies.
Mansour W, Rhein T, Dahm-Daphi J
NUCLEIC ACIDS RES. 2010;38(18):6065-6077.
Prognostic factors and treatment options in patients with leptomeningeal metastases of different primary tumors: a retrospective analysis.
Oechsle K, Lange-Brock V, Krüll A, Bokemeyer C, De Wit M
J CANCER RES CLIN. 2010;136(11):1729-1735.
Validation and simplification of a score predicting survival in patients irradiated for metastatic spinal cord compression.
Rades D, Douglas S, Veninga T, Stalpers L, Hoskin P, Bajrovic A, Adamietz I, Basic H, Dunst J, Schild S
CANCER-AM CANCER SOC. 2010;116(15):3670-3673.
Matched pair analysis comparing surgery followed by radiotherapy and radiotherapy alone for metastatic spinal cord compression.
Rades D, Huttenlocher S, Dunst J, Bajrovic A, Karstens J, Rudat V, Schild S
J CLIN ONCOL. 2010;28(22):3597-3604.
Monte Carlo simulation of mini TEPC microdosimetric spectra: Influence of low energy electrons
Rollet S, Colautti P, Grosswendt B, Moro D, Gargioni E, Conte V, DeNardo L
RADIAT MEAS. 2010;45(10):1330-1333.
Rapid fusion and syncytium formation of heterologous cells upon expression of the FGFRL1 receptor.
Steinberg F, Gerber S, Rieckmann T, Trueb B
J BIOL CHEM. 2010;285(48):37704-37715.
Three-dimensional cell growth confers radioresistance by chromatin density modification.
Storch K, Eke I, Borgmann K, Krause M, Richter C, Becker K, Schröck E, Cordes N
CANCER RES. 2010;70(10):3925-3934.
[Radiation therapy in head and neck cancer. Highlights from ASCO 2010].
Tribius S, Petersen C, Knecht R, Ihloff A
HNO. 2010;58(12):1168-1173.
Limitations associated with analysis of cytogenetic data for biological dosimetry
Vinnikov V, Ainsbury E, Maznyk N, Lloyd D, Rothkamm K
RADIAT RES. 2010;174(4):403-14.
Association of single nucleotide polymorphisms in ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with clinical and cellular radiosensitivity.
Zschenker O, Raabe A, Boeckelmann I, Borstelmann S, Szymczak S, Wellek S, Rades D, Hoeller U, Ziegler A, Dikomey E, Borgmann K
RADIOTHER ONCOL. 2010;97(1):26-32.
Letzte Aktualisierung aus dem FIS: 07.09.2024 - 22:32 Uhr