- Institutsdirektor
Publikationen
Innate T-cell-derived IL-17A/F protects from bleomycin-induced acute lung injury but not bleomycin or adenoviral TGF-β1-induced lung fibrosis in mice
Moog M, Baltes M, Röpke T, Aschenbrenner F, Maus R, Stolper J, Jonigk D, Prinz I, Kolb M, Maus U
EUR J IMMUNOL. 2024 [Epub ahead of print];e2451323.
Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8+ thymocytes
You Y, Dunst J, Ye K, Sandoz P, Reinhardt A, Sandrock I, Comet N, Sarkar R, Yang E, Duprez E, Agudo J, Brown B, Utz P, Kastenmüller W, Gerlach C, Prinz I, Önfelt B, Kreslavsky T
NAT IMMUNOL. 2024;25(8):1367-1382.
Expansion of memory Vδ2 T cells following SARS-CoV-2 vaccination revealed by temporal single-cell transcriptomics
Terzoli S, Marzano P, Cazzetta V, Piazza R, Sandrock I, Ravens S, Tan L, Prinz I, Balin S, Calvi M, Carletti A, Cancellara A, Coianiz N, Franzese S, Frigo A, Voza A, Calcaterra F, Di Vito C, Della Bella S, Mikulak J, Mavilio D
NPJ VACCINES. 2024;9(1):63.
Human γδ T cell Identification from Single-cell RNA Sequencing Datasets by Modular TCR Expression
Song Z, Henze L, Casar C, Schwinge D, Schramm C, Fuss J, Tan L, Prinz I
J LEUKOCYTE BIOL. 2023;114(6):630-638.
RORγt+ c-Maf+ Vγ4+ γδ T cells are generated in the adult thymus but do not reach the periphery
Yang T, Barros-Martins J, Wang Z, Wencker M, Zhang J, Smout J, Gambhir P, Janssen A, Schimrock A, Georgiev H, León-Lara X, Weiss S, Huehn J, Prinz I, Krueger A, Foerster R, Walzer T, Ravens S
CELL REP. 2023;42(10):113230.
IL-17A-producing CD8+ T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts
Picard F, Lutz V, Brichkina A, Neuhaus F, Ruckenbrod T, Hupfer A, Raifer H, Klein M, Bopp T, Pfefferle P, Savai R, Prinz I, Waisman A, Moos S, Chang H, Heinrich S, Bartsch D, Buchholz M, Singh S, Tu M, Klein L, Bauer C, Liefke R, Burchert A, Chung H, Mayer P, Gress T, Lauth M, Gaida M, Huber M
GUT. 2023;72(8):1510-1522.
IL-17 signaling in keratinocytes orchestrates the defense against Staphylococcus aureus skin infection
Moos S, Regen T, Wanke F, Tian Y, Arendholz L, Hauptmann J, Heinen A, Bleul L, Bier K, El Malki K, Reinhardt C, Prinz I, Diefenbach A, Wolz C, Schittek B, Waisman A, Kurschus F
J INVEST DERMATOL. 2023;143(7):1257-1267.e10.
Transcriptional and Clonal Characterization of Cytotoxic T Cells in Crescentic Glomerulonephritis
Mueller A, Zhao Y, Cicek H, Paust H, Sivayoganathan A, Linke A, Wegscheid C, Wiech T, Huber T, Meyer-Schwesinger C, Bonn S, Prinz I, Panzer U, Tiegs G, Krebs C, Neumann K
J AM SOC NEPHROL. 2023;34(6):1003-1018.
Antigen-specific γδ T cells contribute to cytomegalovirus control after stem cell transplantation
Prinz I, Koenecke C
CURR OPIN IMMUNOL. 2023;82:102303.
Individual Epitope-Specific CD8+ T Cell Immune Responses Are Shaped Differently during Chronic Viral Infection
Klein S, Mischke J, Beruldsen F, Prinz I, Antunes D, Cornberg M, Kraft A
PATHOGENS. 2023;12(5):.
Performance comparison of TCR-pMHC prediction tools reveals a strong data dependency
Deng L, Ly C, Abdollahi S, Zhao Y, Prinz I, Bonn S
FRONT IMMUNOL. 2023;14:1128326.
A monoclonal Trd chain supports the development of the complete set of functional γδ T cell lineages
Hahn A, Vogg L, Brey S, Schneider A, Schäfer S, Palmisano R, Pavlova A, Sandrock I, Tan L, Fichtner A, Prinz I, Ravens S, Winkler T
CELL REP. 2023;42(3):112253.
Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
Giannou A, Kempski J, Shiri A, Lücke J, Zhang T, Zhao L, Zazara D, Cortesi F, Riecken K, Amezcua Vesely M, Low J, Xu H, Kaffe E, Garcia-Perez L, Agalioti T, Yamada Y, Jungraithmayr W, Zigmond E, Karstens K, Steglich B, Wagner J, Konczalla L, Carambia A, Schulze K, von Felden J, May P, Briukhovetska D, Bedke T, Brockmann L, Starzonek S, Lange T, Koch C, Riethdorf S, Pelczar P, Böttcher M, Sabihi M, Huber F, Reeh M, Grass J, Wahib R, Seese H, Stüben B, Fard-Aghaie M, Duprée A, Scognamiglio P, Plitzko G, Meiners J, Soukou S, Wittek A, Manthey C, Maroulis I, Arck P, Perez D, Gao B, Zarogiannis S, Strowig T, Pasqualini R, Arap W, Gosálvez J, Kobold S, Prinz I, Guse A, Tachezy M, Ghadban T, Heumann A, Li J, Melling N, Mann O, Izbicki J, Pantel K, Schumacher U, Lohse A, Flavell R, Gagliani N, Huber S
IMMUNITY. 2023;56(1):125-142.e12.
Kidney-resident innate-like memory γδ T cells control chronic Staphylococcus aureus infection of mice
Bertram T, Reimers D, Lory N, Schmidt C, Schmid J, C Heinig L, Bradtke P, Rattay G, Zielinski S, Hellmig M, Bartsch P, Rohde H, Nuñez S, Rosemblatt M, Bono M, Gagliani N, Sandrock I, Panzer U, Krebs C, Meyer-Schwesinger C, Prinz I, Mittrücker H
P NATL ACAD SCI USA. 2023;120(1):e2210490120.
Transcriptomic profile of TNFhigh MAIT cells is linked to B cell response following SARS-CoV-2 vaccination
Marzano P, Balin S, Terzoli S, Della Bella S, Cazzetta V, Piazza R, Sandrock I, Ravens S, Tan L, Prinz I, Calcaterra F, Di Vito C, Cancellara A, Calvi M, Carletti A, Franzese S, Frigo A, Darwish A, Voza A, Mikulak J, Mavilio D
FRONT IMMUNOL. 2023;14:1208662.
Interleukin-23 receptor expressing γδ T cells locally promote early atherosclerotic lesion formation and plaque necrosis in mice
Gil-Pulido J, Amézaga N, Jorgacevic I, Manthey H, Rösch M, Brand T, Cidlinsky P, Schäfer S, Beilhack A, Saliba A, Lorenz K, Boon L, Prinz I, Waisman A, Korn T, Cochain C, Zernecke A
CARDIOVASC RES. 2022;118(14):2932-2945.
Cross-Reactive T Cell Response Exists in Chronic Lymphocytic Choriomeningitis Virus Infection upon Pichinde Virus Challenge
Mischke J, Klein S, Seamann A, Prinz I, Selin L, Ghersi D, Cornberg M, Kraft A
VIRUSES-BASEL. 2022;14(10):.
Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes
Ataide M, Knöpper K, Cruz de Casas P, Ugur M, Eickhoff S, Zou M, Shaikh H, Trivedi A, Grafen A, Yang T, Prinz I, Ohlsen K, Gomez de Agüero M, Beilhack A, Huehn J, Gaya M, Saliba A, Gasteiger G, Kastenmüller W
IMMUNITY. 2022;55(10):1813-1828.e9.
Corrigendum: Systematic pattern analyses of Vδ2+ TCRs reveal that shared "public" Vδ2+ γδ T cell clones are a consequence of rearrangement bias and a higher expansion status
Deng L, Harms A, Ravens S, Prinz I, Tan L
FRONT IMMUNOL. 2022;13:1055103.
OMIP-084: 28-color full spectrum flow cytometry panel for the comprehensive analysis of human γδ T cells
Barros-Martins J, Bruni E, Fichtner A, Cornberg M, Prinz I
CYTOM PART A. 2022;101(10):856-861.
Systematic pattern analyses of Vδ2+ TCRs reveal that shared "public" Vδ2+ γδ T cell clones are a consequence of rearrangement bias and a higher expansion status
Deng L, Harms A, Ravens S, Prinz I, Tan L
FRONT IMMUNOL. 2022;13:.
Healthy-like CD4+ Regulatory and CD4+ Conventional T-Cell Receptor Repertoires Predict Protection from GVHD Following Donor Lymphocyte Infusion
Schneider J, Kuhlmann L, Xiao Y, Raha S, Bernhardt G, Stadler M, Thol F, Heuser M, Eder M, Ganser A, Ravens S, Förster R, Prinz I, Koenecke C, Schultze-Florey C
INT J MOL SCI. 2022;23(18):.
High-Dose Mycobacterium tuberculosis H37rv Infection in IL-17A- and IL-17A/F-Deficient Mice
Ritter K, Behrends J, Rückerl D, Hölscher A, Volz J, Prinz I, Hölscher C
CELLS-BASEL. 2022;11(18):.
A CMV-induced adaptive human Vδ1+ γδ T cell clone recognizes HLA-DR
Deseke M, Rampoldi F, Sandrock I, Borst E, Böning H, Ssebyatika G, Jürgens C, Plückebaum N, Beck M, Hassan A, Tan L, Demera A, Janssen A, Steinberger P, Koenecke C, Viejo-Borbolla A, Messerle M, Krey T, Prinz I
J EXP MED. 2022;219(9):.
Inflammation triggers ILC3 patrolling of the intestinal barrier
Jarade A, Garcia Z, Marie S, Demera A, Prinz I, Bousso P, Di Santo J, Serafini N
NAT IMMUNOL. 2022;23(9):1317-1323.
Intrahepatic CD69+Vδ1 T cells re-circulate in the blood of patients with metastatic colorectal cancer and limit tumor progression
Bruni E, Cimino M, Donadon M, Carriero R, Terzoli S, Piazza R, Ravens S, Prinz I, Cazzetta V, Marzano P, Kunderfranco P, Peano C, Soldani C, Franceschini B, Colombo F, Garlanda C, Mantovani A, Torzilli G, Mikulak J, Mavilio D
J IMMUNOTHER CANCER. 2022;10(7):.
New insights on murine γδ T cells from single-cell multi-omics
Tan L, Inácio D, Prinz I, Silva-Santos B
SCI BULL. 2022;67(11):1102-1104.
γδ T cells license immature B cells to produce a broad range of polyreactive antibodies
Rampoldi F, Donato E, Ullrich L, Deseke M, Janssen A, Demera A, Sandrock I, Bubke A, Juergens A, Swallow M, Sparwasser T, Falk C, Tan L, Trumpp A, Prinz I
CELL REP. 2022;39(8):.
IL-17A-producing γδT cells promote muscle regeneration in a microbiota-dependent manner
Mann A, Hanna B, Muñoz-Rojas A, Sandrock I, Prinz I, Benoist C, Mathis D
J EXP MED. 2022;219(5):.
γδ T Cells Differentially Regulate Bone Loss in Periodontitis Models
Barel O, Aizenbud Y, Tabib Y, Jaber Y, Leibovich A, Horev Y, Zubeidat K, Saba Y, Eli-Berchoer L, Heyman O, Wilensky A, Prinz I, Hovav A
J DENT RES. 2022;101(4):428-436.
Three Layers of Intestinal γδ T Cells Talk Different Languages With the Microbiota
Rampoldi F, Prinz I
FRONT IMMUNOL. 2022;13:.
Interleukin-17 is disease promoting in early stages and protective in late stages of experimental periodontitis
Wilharm A, Binz C, Sandrock I, Rampoldi F, Lienenklaus S, Blank E, Winkel A, Demera A, Hovav A, Stiesch M, Prinz I
PLOS ONE. 2022;17(3):.
γδ intraepithelial lymphocytes facilitate pathological epithelial cell shedding via CD103-mediated granzyme release
Hu M, Golovchenko N, Burns G, Nair P, Kelly T, Agos J, Irani M, Soh W, Zeglinski M, Lemenze A, Bonder E, Sandrock I, Prinz I, Granville D, Keely S, Watson A, Edelblum K
GASTROENTEROLOGY. 2022;162(3):877-889.e7.
The Detrimental Role of Regulatory T Cells in Nonalcoholic Steatohepatitis
Dywicki J, Buitrago-Molina L, Noyan F, Davalos-Misslitz A, Hupa-Breier K, Lieber M, Hapke M, Schlue J, Falk C, Raha S, Prinz I, Koenecke C, Manns M, Wedemeyer H, Hardtke-Wolenski M, Jaeckel E
HEPATOL COMMUN. 2022;6(2):320-333.
Enhanced differentiation of functional human T cells in NSGW41 mice with tissue-specific expression of human interleukin-7
Coppin E, Sundarasetty B, Rahmig S, Blume J, Verheyden N, Bahlmann F, Ravens S, Schubert U, Schmid J, Ludwig S, Geissler K, Guntinas-Lichius O, von Kaisenberg C, Groten T, Platz A, Naumann R, Ludwig B, Prinz I, Waskow C, Krueger A
LEUKEMIA. 2021;35(12):3561-3567.
Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)
Cossarizza A, Chang H, Radbruch A, Abrignani S, Addo R, Akdis M, Andrä I, Andreata F, Annunziato F, Arranz E, Bacher P, Bari S, Barnaba V, Barros-Martins J, Baumjohann D, Beccaria C, Bernardo D, Boardman D, Borger J, Böttcher C, Brockmann L, Burns M, Busch D, Cameron G, Cammarata I, Cassotta A, Chang Y, Chirdo F, Christakou E, Čičin-Šain L, Cook L, Corbett A, Cornelis R, Cosmi L, Davey M, De Biasi S, De Simone G, Del Zotto G, Delacher M, Di Rosa F, Santo J, Diefenbach A, Dong J, Dörner T, Dress R, Dutertre C, Eckle S, Eede P, Evrard M, Falk C, Feuerer M, Fillatreau S, Fiz-Lopez A, Follo M, Foulds G, Fröbel J, Gagliani N, Galletti G, Gangaev A, Garbi N, Garrote J, Geginat J, Gherardin N, Gibellini L, Ginhoux F, Godfrey D, Gruarin P, Haftmann C, Hansmann L, Harpur C, Hayday A, Heine G, Hernández D, Herrmann M, Hoelsken O, Huang Q, Huber S, Huber J, Huehn J, Hundemer M, Hwang W, Iannacone M, Ivison S, Jäck H, Jani P, Keller B, Kessler N, Ketelaars S, Knop L, Knopf J, Koay H, Kobow K, Kriegsmann K, Kristyanto H, Krueger A, Kuehne J, Kunze-Schumacher H, Kvistborg P, Kwok I, Latorre D, Lenz D, Levings M, Lino A, Liotta F, Long H, Lugli E, MacDonald K, Maggi L, Maini M, Mair F, Manta C, Manz R, Mashreghi M, Mazzoni A, McCluskey J, Mei H, Melchers F, Melzer S, Mielenz D, Monin L, Moretta L, Multhoff G, Muñoz L, Muñoz-Ruiz M, Muscate F, Natalini A, Neumann K, Ng L, Niedobitek A, Niemz J, Almeida L, Notarbartolo S, Ostendorf L, Pallett L, Patel A, Percin G, Peruzzi G, Pinti M, Pockley A, Pracht K, Prinz I, Pujol-Autonell I, Pulvirenti N, Quatrini L, Quinn K, Radbruch H, Rhys H, Rodrigo M, Romagnani C, Saggau C, Sakaguchi S, Sallusto F, Sanderink L, Sandrock I, Schauer C, Scheffold A, Scherer H, Schiemann M, Schildberg F, Schober K, Schoen J, Schuh W, Schüler T, Schulz A, Schulz S, Schulze J, Simonetti S, Singh J, Sitnik K, Stark R, Starossom S, Stehle C, Szelinski F, Tan L, Tarnok A, Tornack J, Tree T, van Beek J, van de Veen W, van Gisbergen K, Vasco C, Verheyden N, von Borstel A, Ward-Hartstonge K, Warnatz K, Waskow C, Wiedemann A, Wilharm A, Wing J, Wirz O, Wittner J, Yang J, Yang J
EUR J IMMUNOL. 2021;51(12):2708-3145.
Interleukin-10 improves stroke outcome by controlling the detrimental Interleukin-17A response
Piepke M, Clausen B, Ludewig P, Vienhues J, Bedke T, Javidi E, Rissiek B, Jank L, Brockmann L, Sandrock I, Degenhardt K, Jander A, Roth V, Schädlich I, Prinz I, Flavell R, Kobayashi Y, Renné T, Gerloff C, Huber S, Magnus T, Gelderblom M
J NEUROINFLAMM. 2021;18(1):.
Clonal expansion of CD8+ T cells reflects graft-versus-leukemia activity and precedes durable remission following DLI
Schultze-Florey C, Kuhlmann L, Raha S, Barros-Martins J, Odak I, Tan L, Xiao Y, Ravens S, Hambach L, Venturini L, Stadler M, Eder M, Thol F, Heuser M, Forster R, Ganser A, Prinz I, Koenecke C
BLOOD ADV. 2021;5(21):4485-4499.
αβ T cells replacing dermal and epidermal γδ T cells in Tcrd-/- mice express an MHC-independent TCR repertoire
Binz C, Bubke A, Sandrock I, Prinz I
EUR J IMMUNOL. 2021;51(11):2618-2632.
Interleukin-23 instructs protective multifunctional CD4 T cell responses after immunization with the Mycobacterium tuberculosis subunit vaccine H1 DDA/TDB independently of interleukin-17A
Ritter K, Behrends J, Erdmann H, Rousseau J, Hölscher A, Volz J, Prinz I, Lindenstrøm T, Hölscher C
J MOL MED. 2021;99(11):1585-1602.
NKG2A expression identifies a subset of human Vδ2 T cells exerting the highest antitumor effector functions
Cazzetta V, Bruni E, Terzoli S, Carenza C, Franzese S, Piazza R, Marzano P, Donadon M, Torzilli G, Cimino M, Simonelli M, Bello L, Villa A, Tan L, Ravens S, Prinz I, Supino D, Colombo F, Lugli E, Marcenaro E, Vivier E, Della Bella S, Mikulak J, Mavilio D
CELL REP. 2021;37(3):.
Distribution of major lymphocyte subsets and memory T-cell subpopulations in healthy adults employing GLP-conforming multicolor flow cytometry
Schultze-Florey C, Chukhno E, Goudeva L, Blasczyk R, Ganser A, Prinz I, Förster R, Koenecke C, Odak I
LEUKEMIA. 2021;35(10):3021-3025.
Lack of gamma delta T cells ameliorates inflammatory response after acute intestinal ischemia reperfusion in mice
Funken D, Yu Y, Feng X, Imvised T, Gueler F, Prinz I, Madadi-Sanjani O, Ure B, Kuebler J, Klemann C
SCI REP-UK. 2021;11(1):18628.
γδT Cells Are Essential for Orthodontic Tooth Movement
Wald S, Leibowitz A, Aizenbud Y, Saba Y, Zubeidat K, Barel O, Koren N, Heyman O, Wilharm A, Sandrock I, Fleissig O, Tal Y, Prinz I, Aizenbud D, Chaushu S, Hovav A
J DENT RES. 2021;100(7):731-738.
Influenza A virus-induced thymus atrophy differentially affects dynamics of conventional and regulatory T cell development in mice
Elfaki Y, Robert P, Binz C, Falk C, Bruder D, Prinz I, Floess S, Meyer-Hermann M, Huehn J
EUR J IMMUNOL. 2021;51(5):1166-1181.
A fetal wave of human type 3 effector γδ cells with restricted TCR diversity persists into adulthood
Tan L, Fichtner A, Bruni E, Odak I, Sandrock I, Bubke A, Borchers A, Schultze-Florey C, Koenecke C, Förster R, Jarek M, von Kaisenberg C, Schulz A, Chu X, Zhang B, Li Y, Panzer U, Krebs C, Ravens S, Prinz I
SCI IMMUNOL. 2021;6(58):.
Maturation of the neonatal oral mucosa involves unique epithelium-microbiota interactions
Koren N, Zubeidat K, Saba Y, Horev Y, Barel O, Wilharm A, Heyman O, Wald S, Eli-Berchoer L, Shapiro H, Nadler C, Elinav E, Wilensky A, Prinz I, Bercovier H, Hovav A
CELL HOST MICROBE. 2021;29(2):197-209.e5.
IL-17 controls central nervous system autoimmunity through the intestinal microbiome
Regen T, Isaac S, Amorim A, Núñez N, Hauptmann J, Shanmugavadivu A, Klein M, Sankowski R, Mufazalov I, Yogev N, Huppert J, Wanke F, Witting M, Grill A, Gálvez E, Nikolaev A, Blanfeld M, Prinz I, Schmitt-Kopplin P, Strowig T, Reinhardt C, Prinz M, Bopp T, Becher B, Ubeda C, Waisman A
SCI IMMUNOL. 2021;6(56):.
Peritoneal dialysate-range hypertonic glucose promotes T-cell IL-17 production that induces mesothelial inflammation
Helmke A, Hüsing A, Gaedcke S, Brauns N, Balzer M, Reinhardt M, Hiss M, Shushakova N, de Luca D, Prinz I, Haller H, von Vietinghoff S
EUR J IMMUNOL. 2021;51(2):354-367.
IL-4-Producing Vγ1+/Vδ6+ γδ T Cells Sustain Germinal Center Reactions in Peyer's Patches of Mice
Ullrich L, Lueder Y, Juergens A, Wilharm A, Barros-Martins J, Bubke A, Demera A, Ikuta K, Patzer G, Janssen A, Sandrock I, Prinz I, Rampoldi F
FRONT IMMUNOL. 2021;12:.
Microbiota-dependent expansion of testicular IL-17-producing Vγ6+ γδ T cells upon puberty promotes local tissue immune surveillance
Wilharm A, Brigas H, Sandrock I, Ribeiro M, Amado T, Reinhardt A, Demera A, Hoenicke L, Strowig T, Carvalho T, Prinz I, Ribot J
MUCOSAL IMMUNOL. 2021;14(1):242-252.
Synthetic retinoid AM80 inhibits IL-17 production of gamma delta T cells and ameliorates biliary atresia in mice
Möhn N, Bruni E, Schröder A, Frömmel S, Gueler F, Vieten G, Prinz I, Kuebler J, Petersen C, Klemann C
LIVER INT. 2020;40(12):3031-3041.
From basic research to clinical application of γδ T cells
Déchanet-Merville J, Prinz I
IMMUNOL REV. 2020;298(1):5-9.
Ligand recognition by the γδ TCR and discrimination between homeostasis and stress conditions
Deseke M, Prinz I
CELL MOL IMMUNOL. 2020;17(9):914-924.
PD-L1 Checkpoint Inhibition Narrows the Antigen-Specific T Cell Receptor Repertoire in Chronic Lymphocytic Choriomeningitis Virus Infection
Klein S, Ghersi D, Manns M, Prinz I, Cornberg M, Kraft A
J VIROL. 2020;94(18):.
Microbial exposure drives polyclonal expansion of innate γδ T cells immediately after birth
Ravens S, Fichtner A, Willers M, Torkornoo D, Pirr S, Schöning J, Deseke M, Sandrock I, Bubke A, Wilharm A, Dodoo D, Egyir B, Flanagan K, Steinbrück L, Dickinson P, Ghazal P, Adu B, Viemann D, Prinz I
P NATL ACAD SCI USA. 2020;117(31):18649-18660.
IL-17 regulates DC migration to the peribronchial LNs and allergen presentation in experimental allergic asthma
Jirmo A, Busse M, Happle C, Skuljec J, Dalüge K, Habener A, Grychtol R, DeLuca D, Breiholz O, Prinz I, Hansen G
EUR J IMMUNOL. 2020;50(7):1019-1033.
Reappearance of effector T cells is associated with recovery from COVID-19
Odak I, Barros-Martins J, Bošnjak B, Stahl K, David S, Wiesner O, Busch M, Hoeper M, Pink I, Welte T, Cornberg M, Stoll M, Goudeva L, Blasczyk R, Ganser A, Prinz I, Förster R, Koenecke C, Schultze-Florey C
EBIOMEDICINE. 2020;57:.
TCR repertoire analysis reveals phosphoantigen-induced polyclonal proliferation of Vγ9Vδ2 T cells in neonates and adults
Fichtner A, Bubke A, Rampoldi F, Tan L, Wilharm A, Steinbrück L, Schultze-Florey C, von Kaisenberg C, Prinz I, Herrmann T, Ravens S
J LEUKOCYTE BIOL. 2020;107(6):1023-1032.
Development and Function of γδT Cells in the Oral Mucosa
Hovav A, Wilharm A, Barel O, Prinz I
J DENT RES. 2020;99(5):498-505.
Regulatory T Cells Limit Pneumococcus-Induced Exacerbation of Lung Fibrosis in Mice
Moyé S, Bormann T, Maus R, Sparwasser T, Sandrock I, Prinz I, Warnecke G, Welte T, Gauldie J, Kolb M, Maus U
J IMMUNOL. 2020;204(9):2429-2438.
γδ T-cell Receptors Derived from Breast Cancer-Infiltrating T Lymphocytes Mediate Antitumor Reactivity
Janssen A, Villacorta Hidalgo J, Beringer D, van Dooremalen S, Fernando F, van Diest E, Terrizi A, Bronsert P, Kock S, Schmitt-Gräff A, Werner M, Heise K, Follo M, Straetemans T, Sebestyen Z, Chudakov D, Kasatskaya S, Frenkel F, Ravens S, Spierings E, Prinz I, Küppers R, Malkovsky M, Fisch P, Kuball J
CANCER IMMUNOL RES. 2020;8(4):530-543.
Human γδ TCR Repertoires in Health and Disease
Fichtner A, Ravens S, Prinz I
CELLS-BASEL. 2020;9(4):.
Revisiting the Interaction of γδ T-Cells and B-Cells
Rampoldi F, Ullrich L, Prinz I
CELLS-BASEL. 2020;9(3):.
Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies
Sebestyen Z, Prinz I, Déchanet-Merville J, Silva-Santos B, Kuball J
NAT REV DRUG DISCOV. 2020;19(3):169-184.
Interleukin-17 cytokines: Effectors and targets in psoriasis-A breakthrough in understanding and treatment
Prinz I, Sandrock I, Mrowietz U
J EXP MED. 2020;217(1):.
Donor-derived IL-17A and IL-17F deficiency triggers Th1 allo-responses and increases gut leakage during acute GVHD
Odak I, Depkat-Jakob A, Beck M, Jarek M, Yu Y, Seidler U, David S, Ganser A, Förster R, Prinz I, Koenecke C
PLOS ONE. 2020;15(4):.
NKp46-expressing human gut-resident intraepithelial Vδ1 T cell subpopulation exhibits high antitumor activity against colorectal cancer
Mikulak J, Oriolo F, Bruni E, Roberto A, Colombo F, Villa A, Bosticardo M, Bortolomai I, Lo Presti E, Meraviglia S, Dieli F, Vetrano S, Danese S, Della Bella S, Carvello M, Sacchi M, Cugini G, Colombo G, Klinger M, Spaggiari P, Roncalli M, Prinz I, Ravens S, di Lorenzo B, Marcenaro E, Silva-Santos B, Spinelli A, Mavilio D
JCI INSIGHT. 2019;4(24):.
Focusing of the regulatory T-cell repertoire after allogeneic stem cell transplantation indicates protection from graft-versus-host disease
Odak I, Raha S, Schultze-Florey C, Tavil S, Ravens S, Ganser A, Förster R, Prinz I, Koenecke C
HAEMATOLOGICA. 2019;104(12):e577-e580.
Dangerous γδ T cells in aged mice
Prinz I, Sandrock I
EMBO REP. 2019;20(8):e48678.
Styk1 is specifically expressed in NK1.1+ lymphocytes including NK, γδ T, and iNKT cells in mice, but is dispensable for their ontogeny and function
Wilharm A, Sandrock I, Marotel M, Demera A, Naumann R, Walzer T, Prinz I
EUR J IMMUNOL. 2019;49(5):686-693.
Broad Cytotoxic Targeting of Acute Myeloid Leukemia by Polyclonal Delta One T Cells
Di Lorenzo B, Simões A, Caiado F, Tieppo P, Correia D, Carvalho T, da Silva M, Déchanet-Merville J, Schumacher T, Prinz I, Norell H, Ravens S, Vermijlen D, Silva-Santos B
CANCER IMMUNOL RES. 2019;7(4):552-558.
Robust Identification of Suitable T-Cell Subsets for Personalized CMV-Specific T-Cell Immunotherapy Using CD45RA and CD62L Microbeads
Mangare C, Tischer-Zimmermann S, Riese S, Dragon A, Prinz I, Blasczyk R, Maecker-Kolhoff B, Eiz-Vesper B
INT J MOL SCI. 2019;20(6):.
Germ Line Deletion Reveals a Nonessential Role of Atypical Mitogen-Activated Protein Kinase 6/Extracellular Signal-Regulated Kinase 3
Ronkina N, Schuster-Gossler K, Hansmann F, Kunze-Schumacher H, Sandrock I, Yakovleva T, Lafera J, Baumgärtner W, Krueger A, Prinz I, Gossler A, Kotlyarov A, Gaestel M
MOL CELL BIOL. 2019;39(6):.
The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation
Sparber F, De Gregorio C, Steckholzer S, Ferreira F, Dolowschiak T, Ruchti F, Kirchner F, Mertens S, Prinz I, Joller N, Buch T, Glatz M, Sallusto F, LeibundGut-Landmann S
CELL HOST MICROBE. 2019;25(3):389-403.e6.
miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity
Łyszkiewicz M, Winter S, Witzlau K, Föhse L, Brownlie R, Puchałka J, Verheyden N, Kunze-Schumacher H, Imelmann E, Blume J, Raha S, Sekiya T, Yoshimura A, Frueh J, Ullrich E, Huehn J, Weiss S, Gutierrez M, Prinz I, Zamoyska R, Ziętara N, Krueger A
PLOS BIOL. 2019;17(3):e2006716.
Mutual interplay between IL-17-producing γδT cells and microbiota orchestrates oral mucosal homeostasis
Wilharm A, Tabib Y, Nassar M, Reinhardt A, Mizraji G, Sandrock I, Heyman O, Barros-Martins J, Aizenbud Y, Khalaileh A, Eli-Berchoer L, Elinav E, Wilensky A, Förster R, Bercovier H, Prinz I, Hovav A
P NATL ACAD SCI USA. 2019;116(7):2652-2661.
Hepatitis E Virus (HEV)-Specific T Cell Receptor Cross-Recognition: Implications for Immunotherapy
Soon C, Zhang S, Suneetha P, Antunes D, Manns M, Raha S, Schultze-Florey C, Prinz I, Wedemeyer H, Sällberg Chen M, Cornberg M
FRONT IMMUNOL. 2019;10:2076.
Genetic models reveal origin, persistence and non-redundant functions of IL-17-producing γδ T cells
Sandrock I, Reinhardt A, Ravens S, Binz C, Wilharm A, Martins J, Oberdörfer L, Tan L, Lienenklaus S, Zhang B, Naumann R, Zhuang Y, Krueger A, Förster R, Prinz I
J EXP MED. 2018;215(12):3006-3018.
Pathogenic TH17 inflammation is sustained in the lungs by conventional dendritic cells and Toll-like receptor 4 signaling
Shalaby K, Lyons-Cohen M, Whitehead G, Thomas S, Prinz I, Nakano H, Cook D
J ALLERGY CLIN IMMUN. 2018;142(4):1229-1242.e6.
IL-17-Mediated Immunity Controls Skin Infection and T Helper 1 Response during Experimental Microsporum canis Dermatophytosis
Burstein V, Guasconi L, Beccacece I, Theumer M, Mena C, Prinz I, Cervi L, Herrero M, Masih D, Chiapello L
J INVEST DERMATOL. 2018;138(8):1744-1753.
BCL11B mutations in patients affected by a neurodevelopmental disorder with reduced type 2 innate lymphoid cells
Lessel D, Gehbauer C, Bramswig N, Schluth-Bolard C, Venkataramanappa S, van Gassen K, Hempel M, Haack T, Baresic A, Genetti C, Funari M, Lessel I, Kuhlmann L, Simon R, Liu P, Denecke J, Kuechler A, de Kruijff I, Shoukier M, Lek M, Mullen T, Lüdecke H, Lerario A, Kobbe R, Krieger T, Demeer B, Lebrun M, Keren B, Nava C, Buratti J, Afenjar A, Shinawi M, Guillen Sacoto M, Gauthier J, Hamdan F, Laberge A, Campeau P, Louie R, Cathey S, Prinz I, Jorge A, Terhal P, Lenhard B, Wieczorek D, Strom T, Agrawal P, Britsch S, Tolosa E, Kubisch C
BRAIN. 2018;141(8):2299-2311.
Dissecting Epstein-Barr Virus-Specific T-Cell Responses After Allogeneic EBV-Specific T-Cell Transfer for Central Nervous System Posttransplant Lymphoproliferative Disease
Schultze-Florey R, Tischer S, Kuhlmann L, Hundsdoerfer P, Koch A, Anagnostopoulos I, Ravens S, Goudeva L, Schultze-Florey C, Koenecke C, Blasczyk R, Koehl U, Heuft H, Prinz I, Eiz-Vesper B, Maecker-Kolhoff B
FRONT IMMUNOL. 2018;9:1475.
Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells
Hammer Q, Rückert T, Borst E, Dunst J, Haubner A, Durek P, Heinrich F, Gasparoni G, Babic M, Tomic A, Pietra G, Nienen M, Blau I, Hofmann J, Na I, Prinz I, Koenecke C, Hemmati P, Babel N, Arnold R, Walter J, Thurley K, Mashreghi M, Messerle M, Romagnani C
NAT IMMUNOL. 2018;19(5):453-463.
Gegenseitige Beeinflussung von Immunsystem und Knochen
Kamradt T, Amling M, Dankbar B, Dudeck A, Gunzer M, Ignatius A, Krönke G, Kubatzky K, Pap T, Prinz I, Schett G, Schinke T, Tuckermann J, Waisman A
Z RHEUMATOL. 2018;77(Suppl 1):8-11.
Whodunit? The Contribution of Interleukin (IL)-17/IL-22-Producing γδ T Cells, αβ T Cells, and Innate Lymphoid Cells to the Pathogenesis of Spondyloarthritis
Reinhardt A, Prinz I
FRONT IMMUNOL. 2018;9:885.
The neonatal window of opportunity-early priming for life
Renz H, Adkins B, Bartfeld S, Blumberg R, Farber D, Garssen J, Ghazal P, Hackam D, Marsland B, McCoy K, Penders J, Prinz I, Verhasselt V, von Mutius E, Weiser J, Wesemann D, Hornef M
J ALLERGY CLIN IMMUN. 2018;141(4):1212-1214.
Human γδ T Cell Receptor Repertoires in Peripheral Blood Remain Stable Despite Clearance of Persistent Hepatitis C Virus Infection by Direct-Acting Antiviral Drug Therapy
Ravens S, Hengst J, Schlapphoff V, Deterding K, Dhingra A, Schultze-Florey C, Koenecke C, Cornberg M, Wedemeyer H, Prinz I
FRONT IMMUNOL. 2018;9:510.
Innately versatile: γδ17 T cells in inflammatory and autoimmune diseases
Papotto P, Reinhardt A, Prinz I, Silva-Santos B
J AUTOIMMUN. 2018;87:26-37.
IL-17 and TNF-α Are Key Mediators of Moraxella catarrhalis Triggered Exacerbation of Allergic Airway Inflammation
Alnahas S, Hagner S, Raifer H, Kilic A, Gasteiger G, Mutters R, Hellhund A, Prinz I, Pinkenburg O, Visekruna A, Garn H, Steinhoff U
FRONT IMMUNOL. 2017;8:1562.
Impact of CCR7 on T-Cell Response and Susceptibility to Yersinia pseudotuberculosis Infection
Pezoldt J, Pisano F, Heine W, Pasztoi M, Rosenheinrich M, Nuss A, Pils M, Prinz I, Förster R, Huehn J, Dersch P
J INFECT DIS. 2017;216(6):752-760.
Prevention of colitis-associated cancer by selective targeting of immunoproteasome subunit LMP7
Vachharajani N, Joeris T, Luu M, Hartmann S, Pautz S, Jenike E, Pantazis G, Prinz I, Hofer M, Steinhoff U, Visekruna A
ONCOTARGET. 2017;8(31):50447-50459.
CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17-Producing γδ T Cells in Stroke
Arunachalam P, Ludewig P, Melich P, Arumugam T, Gerloff C, Prinz I, Magnus T, Gelderblom M
STROKE. 2017;48(7):1957-1965.
Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections
Hassane M, Demon D, Soulard D, Fontaine J, Keller L, Patin E, Porte R, Prinz I, Ryffel B, Kadioglu A, Veening J, Sirard J, Faveeuw C, Lamkanfi M, Trottein F, Paget C
MUCOSAL IMMUNOL. 2017;10(4):1056-1068.
The Microbiome Activates CD4 T-cell-mediated Immunity to Compensate for Increased Intestinal Permeability
Edelblum K, Sharon G, Singh G, Odenwald M, Sailer A, Cao S, Ravens S, Thomsen I, El Bissati K, McLeod R, Dong C, Gurbuxani S, Prinz I, Mazmanian S, Turner J
CELL MOL GASTROENTER. 2017;4(2):285-297.
Eomes expression reports the progressive differentiation of IFN-γ-producing Th1-like γδ T cells
Lino C, Barros-Martins J, Oberdörfer L, Walzer T, Prinz I
EUR J IMMUNOL. 2017;47(6):970-981.
Reply to Comment : Could γ/δ T Cells Explain Adverse Effects of Zoledronic Acid? Comment on the Article by Reinhardt et al. 2016
Reinhardt A, Prinz I
ARTHRITIS RHEUMATOL. 2017;69(6):1339-1341.
Human γδ T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection
Ravens S, Schultze-Florey C, Raha S, Sandrock I, Drenker M, Oberdörfer L, Reinhardt A, Ravens I, Beck M, Geffers R, von Kaisenberg C, Heuser M, Thol F, Ganser A, Förster R, Koenecke C, Prinz I
NAT IMMUNOL. 2017;18(4):393-401.
Interleukin-23-Dependent γ/δ T Cells Produce Interleukin-17 and Accumulate in the Enthesis, Aortic Valve, and Ciliary Body in Mice
Reinhardt A, Yevsa T, Worbs T, Lienenklaus S, Sandrock I, Oberdörfer L, Korn T, Weiss S, Förster R, Prinz I
ARTHRITIS RHEUMATOL. 2016;68(10):2476-86.
Disruption of de novo fatty acid synthesis via acetyl-CoA carboxylase 1 inhibition prevents acute graft-versus-host disease
Raha S, Raud B, Oberdörfer L, Castro C, Schreder A, Freitag J, Longerich T, Lochner M, Sparwasser T, Berod L, Koenecke C, Prinz I
EUR J IMMUNOL. 2016;46(9):2233-8.
Brief Report: Arthritis in KRN T Cell Receptor-Transgenic Mice Does Not Require Interleukin-17 or Th17 Cells
Auger J, Cowan H, Engelson B, Kashem S, Prinz I, Binstadt B
ARTHRITIS RHEUMATOL. 2016;68(8):1849-55.
IL-17 is not essential for inflammation and chronic pelvic pain development in an experimental model of chronic prostatitis/chronic pelvic pain syndrome
Motrich R, Breser M, Sánchez L, Godoy G, Prinz I, Rivero V
PAIN. 2016;157(3):585-597.
Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation
Yang B, Hagemann S, Mamareli P, Lauer U, Hoffmann U, Beckstette M, Föhse L, Prinz I, Pezoldt J, Suerbaum S, Sparwasser T, Hamann A, Floess S, Huehn J, Lochner M
MUCOSAL IMMUNOL. 2016;9(2):444-57.
Interleukin 17, Produced by γδ T Cells, Contributes to Hepatic Inflammation in a Mouse Model of Biliary Atresia and Is Increased in Livers of Patients
Klemann C, Schröder A, Dreier A, Möhn N, Dippel S, Winterberg T, Wilde A, Yu Y, Thorenz A, Gueler F, Jörns A, Tolosa E, Leonhardt J, Haas J, Prinz I, Vieten G, Petersen C, Kuebler J
GASTROENTEROLOGY. 2016;150(1):229-241.e5.
MicroRNA-181a/b-1 Is Not Required for Innate γδ NKT Effector Cell Development
Sandrock I, Ziętara N, Łyszkiewicz M, Oberdörfer L, Witzlau K, Krueger A, Prinz I
PLOS ONE. 2015;10(12):e0145010.
γδ T cells come to stay: Innate skin memory in the Aldara model
Prinz I, Sandrock I
EUR J IMMUNOL. 2015;45(11):2994-7.
Multicongenic fate mapping quantification of dynamics of thymus colonization
Ziętara N, Łyszkiewicz M, Puchałka J, Witzlau K, Reinhardt A, Förster R, Pabst O, Prinz I, Krueger A
J EXP MED. 2015;212(10):1589-601.
Testosterone Suppresses Hepatic Inflammation by the Downregulation of IL-17, CXCL-9, and CXCL-10 in a Mouse Model of Experimental Acute Cholangitis
Schwinge D, Carambia A, Quaas A, Krech T, Wegscheid C, Tiegs G, Prinz I, Lohse A, Herkel J, Schramm C
J IMMUNOL. 2015;194(6):2522-30.
A clonotypic Vγ4Jγ1/Vδ5Dδ2Jδ1 innate γδ T-cell population restricted to the CCR6⁺CD27⁻ subset
Kashani E, Föhse L, Raha S, Sandrock I, Oberdörfer L, Koenecke C, Suerbaum S, Weiss S, Prinz I
NAT COMMUN. 2015;6:6477.
Limited niche availability suppresses murine intrathymic dendritic-cell development from noncommitted progenitors
Łyszkiewicz M, Ziętara N, Föhse L, Puchałka J, Diestelhorst J, Witzlau K, Prinz I, Schambach A, Krueger A
BLOOD. 2015;125(3):457-64.
Ontogeny of Innate T Lymphocytes - Some Innate Lymphocytes are More Innate than Others
Vermijlen D, Prinz I
FRONT IMMUNOL. 2014;5:486.
γδ T cell subsets play opposing roles in regulating experimental autoimmune encephalomyelitis
Blink S, Caldis M, Goings G, Harp C, Malissen B, Prinz I, Xu D, Miller S
CELL IMMUNOL. 2014;290(1):39-51.
Visualization and quantification of monoallelic TCRα gene rearrangement in αβ T cells
Winter M, Kashani E, Chennupati V, Föhse L, Prinz I
IMMUNOL CELL BIOL. 2014;92(5):409-16.
CCR7-mediated migration in the thymus controls γδ T-cell development
Reinhardt A, Ravens S, Fleige H, Haas J, Oberdörfer L, Łyszkiewicz M, Förster R, Prinz I
EUR J IMMUNOL. 2014;44(5):1320-9.
IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs
Fleige H, Ravens S, Moschovakis G, Bölter J, Willenzon S, Sutter G, Häussler S, Kalinke U, Prinz I, Förster R
J EXP MED. 2014;211(4):643-51.
T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow
Daussy C, Faure F, Mayol K, Viel S, Gasteiger G, Charrier E, Bienvenu J, Henry T, Debien E, Hasan U, Marvel J, Yoh K, Takahashi S, Prinz I, de Bernard S, Buffat L, Walzer T
J EXP MED. 2014;211(3):563-77.
Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis
Hammerich L, Bangen J, Govaere O, Zimmermann H, Gassler N, Huss S, Liedtke C, Prinz I, Lira S, Luedde T, Roskams T, Trautwein C, Heymann F, Tacke F
HEPATOLOGY. 2014;59(2):630-42.
Induced and thymus-derived Foxp3⁺ regulatory T cells share a common niche
Huang Y, Haist V, Baumgärtner W, Föhse L, Prinz I, Suerbaum S, Floess S, Huehn J
EUR J IMMUNOL. 2014;44(2):460-8.
Differential postselection proliferation dynamics of αβ T cells, Foxp3+ regulatory T cells, and invariant NKT cells monitored by genetic pulse labeling
Föhse L, Reinhardt A, Oberdörfer L, Schmitz S, Förster R, Malissen B, Prinz I
J IMMUNOL. 2013;191(5):2384-92.
Functional development of γδ T cells
Prinz I, Silva-Santos B, Pennington D
EUR J IMMUNOL. 2013;43(8):1988-94.
Donor Vδ1+ γδ T cells expand after allogeneic hematopoietic stem cell transplantation and show reactivity against CMV-infected cells but not against progressing B-CLL
Prinz I, Thamm K, Port M, Weissinger E, Stadler M, Gabaev I, Jacobs R, Ganser A, Koenecke C
EXP HEMATOL ONCOL. 2013;2(1):14.
Critical role for miR-181a/b-1 in agonist selection of invariant natural killer T cells
Ziętara N, Łyszkiewicz M, Witzlau K, Naumann R, Hurwitz R, Langemeier J, Bohne J, Sandrock I, Ballmaier M, Weiss S, Prinz I, Krueger A
P NATL ACAD SCI USA. 2013;110(18):7407-12.
The natural and the inducible interleukin (IL)-17-producing γδ T cells
Chien Y, Zeng X, Prinz I
TRENDS IMMUNOL. 2013;34(4):151-4.
Development of interleukin-17-producing γδ T cells is restricted to a functional embryonic wave
Haas J, Ravens S, Düber S, Sandrock I, Oberdörfer L, Kashani E, Chennupati V, Föhse L, Naumann R, Weiss S, Krueger A, Förster R, Prinz I
IMMUNITY. 2012;37(1):48-59.
Therapeutic potential of induced and natural FoxP3(+) regulatory T cells for the treatment of Graft-versus-host disease
Prinz I, Koenecke C
ARCH IMMUNOL THER EX. 2012;60(3):183-90.
Dynamic migration of γδ intraepithelial lymphocytes requires occludin
Edelblum K, Shen L, Weber C, Marchiando A, Clay B, Wang Y, Prinz I, Malissen B, Sperling A, Turner J
P NATL ACAD SCI USA. 2012;109(18):7097-102.
γδ T cells are not alone
Prinz I, Föhse L
IMMUNOL CELL BIOL. 2012;90(4):370-1.
Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine
Lindner C, Wahl B, Föhse L, Suerbaum S, Macpherson A, Prinz I, Pabst O
J EXP MED. 2012;209(2):365-77.
Induction of BALT in the absence of IL-17
Fleige H, Haas J, Stahl F, Willenzon S, Prinz I, Förster R
NAT IMMUNOL. 2012;13(1):1; author reply 2.
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
Gelderblom M, Weymar A, Bernreuther C, Velden J, Arunachalam P, Steinbach K, Orthey E, Arumugam T, Leypoldt F, Simova O, Thom V, Friese M, Prinz I, Hölscher C, Glatzel M, Korn T, Gerloff C, Tolosa E, Magnus T
BLOOD. 2012;120(18):3793-3802.
IFN-γ production by allogeneic Foxp3+ regulatory T cells is essential for preventing experimental graft-versus-host disease.
Koenecke C, Lee C, Thamm K, Föhse L, Schafferus M, Mittrücker H, Floess S, Huehn J, Ganser A, Förster R, Prinz I
J IMMUNOL. 2012;189(6):2890-2896.
Shift of graft-versus-host-disease target organ tropism by dietary vitamin A
Koenecke C, Prinz I, Bubke A, Schreder A, Lee C, Pabst O, Förster R
PLOS ONE. 2012;7(5):e38252.
Deficient CCR7 signaling promotes TH2 polarization and B-cell activation in vivo
Moschovakis G, Bubke A, Dittrich-Breiholz O, Braun A, Prinz I, Kremmer E, Förster R
EUR J IMMUNOL. 2012;42(1):48-57.
IL-17A production by renal γδ T cells promotes kidney injury in crescentic GN.
Turner J, Krebs C, Tittel A, Paust H, Meyer-Schwesinger C, Bennstein S, Steinmetz O, Prinz I, Magnus T, Korn T, Stahl R, Kurts C, Panzer U
J AM SOC NEPHROL. 2012;23(9):1486-1495.
High TCR diversity ensures optimal function and homeostasis of Foxp3+ regulatory T cells
Föhse L, Suffner J, Suhre K, Wahl B, Lindner C, Lee C, Schmitz S, Haas J, Lamprecht S, Koenecke C, Bleich A, Hämmerling G, Malissen B, Suerbaum S, Förster R, Prinz I
EUR J IMMUNOL. 2011;41(11):3101-13.
Commensal gut flora reduces susceptibility to experimentally induced colitis via T-cell-derived interleukin-10
Pils M, Bleich A, Prinz I, Fasnacht N, Bollati-Fogolin M, Schippers A, Rozell B, Müller W
INFLAMM BOWEL DIS. 2011;17(10):2038-46.
Dynamics of the interaction of γδ T cells with their neighbors in vivo
Prinz I
CELL MOL LIFE SCI. 2011;68(14):2391-8.
Genetic labeling reveals altered turnover and stability of innate lymphocytes in latent mouse cytomegalovirus infection
Busche A, Schmitz S, Fleige H, Robbins S, Walzer T, Stewart C, Förster R, Messerle M, Prinz I
J IMMUNOL. 2011;186(5):2918-25.
Expression of miRNAs miR-133b and miR-206 in the Il17a/f locus is co-regulated with IL-17 production in αβ and γδ T cells
Haas J, Nistala K, Petermann F, Saran N, Chennupati V, Schmitz S, Korn T, Wedderburn L, Förster R, Krueger A, Prinz I
PLOS ONE. 2011;6(5):e20171.
Constant TCR triggering suggests that the TCR expressed on intestinal intraepithelial γδ T cells is functional in vivo
Malinarich F, Grabski E, Worbs T, Chennupati V, Haas J, Schmitz S, Candia E, Quera R, Malissen B, Förster R, Hermoso M, Prinz I
EUR J IMMUNOL. 2010;40(12):3378-88.
Letzte Aktualisierung aus dem FIS: 02.11.2024 - 23:36 Uhr